Implementation of Meta-analysis for Effect Combination of Regression Coefficient in R Software with metafor Package_Chinese Journal of Evidence-Based Medicine

Authors：

 ZHANGYun-quan ,  MALu , FENGRen-jie , ZHUYao-hui , LICun-lu

Department of Epidemiology and Health Statistics, School of Public Health, Wuhan University, Wuhan 430071, China;

Corresponding?author：

MALu, Email: malu@whu.edu.cn

Keywords：

Meta-analysis; R software; metafor package; Regression coefficient

DOI：

10.7507/1672-2531.20150062

Video：

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Objective To introduce the method of meta-analysis for effect combination of regression coefficient conducted with the metafor package in R software. Methods By using the data of a published meta-analysis as an example, the detailed process of meta-analysis for regression coefficient was presented with metafor package in R. Results The results of meta-analysis conducted with metaphor package in R were the same as the published literature. Conclusion As a completely free open source software for statistical analysis, R can conduct meta-analysis for effect combination of regression coefficient flexibly and precisely, and should be expanded in the future meta-analysis.

Citation： ZHANGYun-quan, MALu, FENGRen-jie, ZHUYao-hui, LICun-lu. Implementation of Meta-analysis for Effect Combination of Regression Coefficient in R Software with metafor Package. Chinese Journal of Evidence-Based Medicine, 2015, 15(3): 367-372. doi: 10.7507/1672-2531.20150062 Copy

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9.	Hayashino Y, Noguchi Y, Fukui T. Systematic evaluation and comparison of statistical tests for publication bias. J Epidemiol, 2005, 15(6):235-243.

1. Glass GV. Primary, secondary, and meta-analysis of research. Educ Res, 1976, 3-8.
2. 曾憲濤, 冷衛東, 李勝, 等. 如何正確理解及使用GRADE系統. 中國循證醫學雜志, 2011, 11(9):985-990.
3. 曾憲濤, 冷衛東, 郭毅, 等. Meta分析系列之一:Meta 分析的類型. 中國循證心血管醫學雜志, 2012, 4(1):3-5.
4. 曾憲濤, 田國祥, 董圣杰. Meta 分析系列之二:Meta 分析的軟件. 中國循證心血管醫學雜志, 2012, 4(2):89-91.
5. Viechtbauer W. Conducting meta-analyses in R with the metafor package. J Stat Softw, 2010, 36(3):1-48.
6. 董圣杰, 曾憲濤, 郭毅. R 軟件 Metafor 程序包在 Meta 分析中的應用. 中國循證醫學雜志, 2012, 12(9):1141-1147.
7. Stieb DM, Chen L, Eshoul M, et al. Ambient air pollution, birth weight and preterm birth:a systematic review and meta-analysis. Environ Res, 2012, 117:100-111.
8. 石修權, 王增珍. Egger's test 與 Begg's test 的功效差異比較與原因分析. 華中科技大學學報:醫學版, 2009, 38(1):91-93.
9. Hayashino Y, Noguchi Y, Fukui T. Systematic evaluation and comparison of statistical tests for publication bias. J Epidemiol, 2005, 15(6):235-243.

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