Low Dose MSCT Diagnosis of Pulmonary Fungal Infection_Chinese Journal of Respiratory and Critical Care Medicine

Authors：

QiYueyong ^* , GuTao ^* , CaiYuanqing , WangShuang , ZhouYu ,  ZouLiguang

Department of Radiology, Xinqiao Hospital, The Third Military Medical University, Chongqing, 400037, China;

Corresponding?author：

ZouLiguang, Email: 1320961696@qq.com

Keywords：

Fungal infections; Lung; Multi-slice spiral computed tomography; Diagnosis

DOI：

10.7507/1671-6205.2016037

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Objective To explore the diagnosis value of the low dose multi-slice spiral computed tomography (MSCT) imaging in pulmonary fungal infection in order to improve its diagnosis level. Methods CT manifestations of 106 cases of pulmonary fungal infection confirmed by operation, pathology, mycetes cultivation and follow-ups of clinical therapy were retrospectively analyzed. All cases underwent low dose MSCT examinations including CARE dose 4D and sinogram affirmed iterative reconstruction technology, and 6 cases underwent contrast-enhanced CT scanning. Results Among the basic MSCT findings of pulmonary fungal infection, they showed patch-nodular type in 54 cases, solid variant in 38 cases, and tumor type in 14 cases. In all cases, 91 cases displayed as mulifocality, 83 cases as polymorphism and 78 cases as polytropy. Among the 106 cases with comparative distinctive MSCT manifestations, bud of branch sign were showed in 39 cases, halo sign in 32 cases, wedge shape consolidation in 19 cases, ice needle sign in 15 cases, crescentic sign in 11 cases, air ring sign in 6 cases, and contra-halo sign in 4 cases. The nodules in the cavities were not enhanced in enhanced scan in 5 cases. Conclusions There are some distinctive MSCT findings in patients with pulmonary fungal infection. Pulmonary fungal infection can be diagnosed with typical MSCT findings in close combination with the clinical information.

Citation： QiYueyong, GuTao, CaiYuanqing, WangShuang, ZhouYu, ZouLiguang. Low Dose MSCT Diagnosis of Pulmonary Fungal Infection. Chinese Journal of Respiratory and Critical Care Medicine, 2016, 15(2): 158-160. doi: 10.7507/1671-6205.2016037 Copy

1.	?Miki N, Yasuhiro F, Masaki Y, et al.Epidemiology of invasive fungal infections after liver transplantation and the risk factors of late-onset invasive aspergillosis.J Infect Chemother, 2016, 22:84-89.
2.	馮春來, 施毅.肺曲霉球診治進展.中國呼吸與危重監護雜志, 2014, 13:427-429.
3.	Pratibha G.Pulmonary fungal infections.Curr Med Res Pract, 2015, 5:221-227.
4.	Andreas C, Margaret CL, Andrew CY, et al.CT patterns of fungal pulmonary infections of the lung:Comparison of standard-dose and simulated low-dose CT.Eur J Radiol, 2012, 81:2860-2866.
5.	Martinez DR, Ananda-Rajah MR, Suominen H, et al.Automatic detection of patients with invasive fungal disease from free-text computed tomography (CT) scans.J Biomed Inform, 2015, 53:251-260.
6.	Taisa DG, Dante LE, Edson M.Pulmonary infections following bone marrow transplantation:High-resolution CT findings in 35 paediatric patients.European J Radiol, 2008, 66:117-121.
7.	Gafter-Gvili A, Paul M, Bernstine H, et al. The role of ¹⁸F-FDG PET/CT for the diagnosis of infections in patients with hematological malignancies and persistent febrile neutropenia. Leuk Res, 2013, 37:1057-1062.
8.	Vos FJ, Donnelly JP, Oyen WJ, et al. ¹⁸F-FDG PET /CT for diagnosing infectious complications in patients with severe neutropenia after intensive chemotherapy for haematological malignancy or stem cell transplantation. Eur J Nucl Med Mol Imaging, 2012, 39:120.

1. ?Miki N, Yasuhiro F, Masaki Y, et al.Epidemiology of invasive fungal infections after liver transplantation and the risk factors of late-onset invasive aspergillosis.J Infect Chemother, 2016, 22:84-89.
2. 馮春來, 施毅.肺曲霉球診治進展.中國呼吸與危重監護雜志, 2014, 13:427-429.
3. Pratibha G.Pulmonary fungal infections.Curr Med Res Pract, 2015, 5:221-227.
4. Andreas C, Margaret CL, Andrew CY, et al.CT patterns of fungal pulmonary infections of the lung:Comparison of standard-dose and simulated low-dose CT.Eur J Radiol, 2012, 81:2860-2866.
5. Martinez DR, Ananda-Rajah MR, Suominen H, et al.Automatic detection of patients with invasive fungal disease from free-text computed tomography (CT) scans.J Biomed Inform, 2015, 53:251-260.
6. Taisa DG, Dante LE, Edson M.Pulmonary infections following bone marrow transplantation:High-resolution CT findings in 35 paediatric patients.European J Radiol, 2008, 66:117-121.
7. Gafter-Gvili A, Paul M, Bernstine H, et al. The role of ¹⁸F-FDG PET/CT for the diagnosis of infections in patients with hematological malignancies and persistent febrile neutropenia. Leuk Res, 2013, 37:1057-1062.
8. Vos FJ, Donnelly JP, Oyen WJ, et al. ¹⁸F-FDG PET /CT for diagnosing infectious complications in patients with severe neutropenia after intensive chemotherapy for haematological malignancy or stem cell transplantation. Eur J Nucl Med Mol Imaging, 2012, 39:120.

Previous Article
Interstitial Pneumonia with Autoimmune Features: A Single Center Study
Next Article
Airway Reconstruction supported by Extracorporeal Membrane Oxygenation

Chinese Journal of Respiratory and Critical Care Medicine

Low Dose MSCT Diagnosis of Pulmonary Fungal Infection

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content