嗅神經母細胞瘤源性氣管支氣管轉移瘤一例報告并文獻復習_Chinese Journal of Respiratory and Critical Care Medicine

Authors：

張偉 , 楊夢 ,  李強

上海長海醫院呼吸與危重癥醫學科（上海 200433）;

Corresponding?author：

李強, Email: liqressh@hotmail.com

Keywords：

嗅神經母細胞瘤; 氣管支氣管轉移瘤; 支氣管介入治療

DOI：

10.7507/1671-6205.2016018

Video：

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Abstract Full text Figures/Tables Video References Cited by

目的總結嗅神經母細胞瘤源性氣管支氣管轉移瘤的診斷及治療現狀。方法報道我院收治的1例嗅神經母細胞瘤源性氣管支氣管轉移瘤患者, 并查閱相關報道資料進行文獻復習與總結。結果患者男性, 55歲, 因"咳嗽2個月, 伴氣促、聲音嘶啞半個月"收治入院。外院頸部及胸部CT示氣管上段新生物(2個), 氣管重度阻塞。入院后行電子支氣管鏡示氣管內新生物, 氣管重度狹窄。行鏡下病理活檢, 新生物行圈套、基底部高頻電凝及氬離子束凝固術。患者經支氣管鏡治療后, 咳嗽、氣促癥狀緩解, 病情穩定。3個月后出現右中肺、左肺、縱隔淋巴結及左側胸膜多發轉移瘤。患者拒絕進一步治療, 自動出院。結論對于既往有肺外惡性腫瘤史的患者, 當其出現咳嗽、咯血、呼吸困難等呼吸道相關癥狀時, 除考慮肺部轉移外, 也應考慮氣管支氣管轉移, 盡快予以影像學檢查、支氣管鏡檢, 甚至病理及免疫組化活檢等明確診斷。及早積極治療有助于改善氣管支氣管轉移瘤患者生存質量甚至預后。

Citation： 張偉, 楊夢, 李強. 嗅神經母細胞瘤源性氣管支氣管轉移瘤一例報告并文獻復習. Chinese Journal of Respiratory and Critical Care Medicine, 2016, 15(1): 75-77. doi: 10.7507/1671-6205.2016018 Copy

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7.	Sorensen JB.Endobronchial metastases from extrapulmonary solid tumors.Acta Oncologica, 2003, 43:73-79.
8.	Salud A, Porcel JM, Rovirosa A, et al.Endobronchial metastatic disease.Analysis of 32 cases.J Surg Oncol, 1996, 62:249-252.
9.	Lee SH, Jung JY, Kim DH, et al.Endobronchial metastases from extrathoracic malignancy.Yonsei Med J, 2013, 54:403-409.
10.	王西華, 李萍, 李名娣, 等.支氣管轉移癌的內鏡下表現和病理診斷.中國內鏡雜志, 2014, 20:381-384.
11.	項瑞芬.氣管支氣管轉移癌臨床分析.中國現代藥物應用, 2013, 7:74-75.
12.	白沖, 黃怡, 李強, 等.氣管支氣管轉移癌62例臨床分析.中華內科雜志, 2007, 46:806-809.
13.	王莉.氣管支氣管轉移癌78例臨床分析.臨床醫學, 2014, 34:42-43.
14.	Dong A, Zhao T, Wang Y, et al.FDG PET/CT in endobronchial metastases fromextrathoracic malignancies.Clin Nucl Med, 2014, 39:446-449.
15.	劉曉琴, 王琪, 房居高.嗅神經母細胞瘤的診治進展, 2013, 37:122-124.
16.	Carlin BW, Harrell JH 2nd, Olson LK, et al.Endobronchial metastases due to colorectal carcinoma.Chest, 1989, 96:1110-1114.
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1. Kiryu T, Hoshi H, Matsui E, et al.Endotracheal/endobronchial metastases:clinicopathologic study with special reference to developmental modes.Chest, 2001, 119:768-775.
2. Marchioni A, Lasagni A, Busca A, et al.Endobronchial metastasis:An epidemiologic and clinicopathologic study of 174 consecutive cases.Lung Cancer, 2014, 84:222-228.
3. Klas JV, Rothenberger DA, Wond WD, et al. Malignant tumors of the anal canal:the spectrum of disease, treatment and outcomes.Cancer, 1999, 85:1686-1693.
4. Kreisman H, Wolkove N, Finkelstein HS, et al.Breast cancer and thoracic metastases:review of 119 patients.Thorax, 1983, 38:175-179.
5. Willis RA.The spread of tumors in the human body.Lancet, 1973, 1(8482):683-684.
6. Braman SS, Whitcomb ME.Endobronchial metastasis.Arch Intern Med, 1975, 135:543-547.
7. Sorensen JB.Endobronchial metastases from extrapulmonary solid tumors.Acta Oncologica, 2003, 43:73-79.
8. Salud A, Porcel JM, Rovirosa A, et al.Endobronchial metastatic disease.Analysis of 32 cases.J Surg Oncol, 1996, 62:249-252.
9. Lee SH, Jung JY, Kim DH, et al.Endobronchial metastases from extrathoracic malignancy.Yonsei Med J, 2013, 54:403-409.
10. 王西華, 李萍, 李名娣, 等.支氣管轉移癌的內鏡下表現和病理診斷.中國內鏡雜志, 2014, 20:381-384.
11. 項瑞芬.氣管支氣管轉移癌臨床分析.中國現代藥物應用, 2013, 7:74-75.
12. 白沖, 黃怡, 李強, 等.氣管支氣管轉移癌62例臨床分析.中華內科雜志, 2007, 46:806-809.
13. 王莉.氣管支氣管轉移癌78例臨床分析.臨床醫學, 2014, 34:42-43.
14. Dong A, Zhao T, Wang Y, et al.FDG PET/CT in endobronchial metastases fromextrathoracic malignancies.Clin Nucl Med, 2014, 39:446-449.
15. 劉曉琴, 王琪, 房居高.嗅神經母細胞瘤的診治進展, 2013, 37:122-124.
16. Carlin BW, Harrell JH 2nd, Olson LK, et al.Endobronchial metastases due to colorectal carcinoma.Chest, 1989, 96:1110-1114.
17. Quantrill SJ, Burt PA, Barber PV, et al.Treatment of endobronchial metastases with intraluminal radiotherapy.Respir Med, 2000, 94:369-372.

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嗅神經母細胞瘤源性氣管支氣管轉移瘤一例報告并文獻復習

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