The Etiology Study on Severe Community-Acquired Pneumonia in Adults in Emergency Department_Chinese Journal of Respiratory and Critical Care Medicine

Authors：

LiuZhen ¹ , LiuQimeng ² , ZhaoLi ¹ , YangJiankun ¹ , LiJing ¹ ,  YeHuan ²

1. Emergency Department, Fuxing Hospital, Capital Medical University, Beijing, 100038, China;
2. ;

Corresponding?author：

YeHuan, Email: yedahuan@yeah.net

Keywords：

Severe community-acquired pneumonia; Emergency department; Aetiology

DOI：

10.7507/1671-6205.2015011

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Objective To investigate the etiologic feature and prognosis of adult patients with severe community-acquired pneumonia (SCAP). Methods According to the guideline on the diagnosis and treatment of community-acquired pneumonia in 2006, 105 patients with SCAP were included in the study. The proportion of pathogens (including multiple resistant bacteria) and mortality rate were recorded. Appropriate statistical methods were selected and all data were analyzed by using SPSS Version 18.0 computerized program. Results The predominant pathogen with SCAP was Pseudomonas aeruginosa, followed by Klebsiella pneumoniae, Staphylococcus aureus, and Legionella pneumophila. In death cases, Klebsiella pneumoniae was the most common pathogen, followed by Staphylococcus aureus. It was showed in the drug sensitivity test that most pathogens were drug-sensitive strains. The patients with tumor had higher risks to get infected with Gram-negative bacillus. Conclusions The etiology of patients with SCAP in our emergency department is given priority to Gram-negative bacillus and sensitive strains, of which Pseudomonas aeruginosa and Klebsiella pneumoniae are predominant. As for the Gram-positive cocci, Staphylococcus aureus is the most common pathogen. Legionella pneumophila is the most common pathogen in atypical pathogens, which only account for a small proportion of the aetiology of SCAP. Patients with Klebsiella pneumoniae and Staphylococcus aureus infections are associated with poor prognosis.

Citation： LiuZhen, LiuQimeng, ZhaoLi, YangJiankun, LiJing, YeHuan. The Etiology Study on Severe Community-Acquired Pneumonia in Adults in Emergency Department. Chinese Journal of Respiratory and Critical Care Medicine, 2015, 14(1): 42-47. doi: 10.7507/1671-6205.2015011 Copy

1.	查日田.重癥社區獲得性肺炎評價的研究進展.臨床肺科雜志, 2012, 17:2266-2268.
2.	Houck PM, Bratzler DW, Nsa W, et al. Timing of antibiotic administration and outcomes for Medicare patients hospitalized with community-acquired pneumonia. Arch Intern Med, 2004, 164:637-644.
3.	中華醫學會呼吸病學分會.社區獲得性肺炎診斷及治療方案.中華結核和呼吸雜志, 2006, 29:651-655.
4.	葛均波, 徐永健, 主編.內科學.北京:人民衛生出版社, 2013, 9.
5.	Schaaf B, Kruse J, Rupp J, et al. Sepsis severity predicts outcome in community-acquired pneumococcal pneumonia. Eur Respir J, 2007, 30:517-524.
6.	劉又寧, 陳民鈞, 趙鐵梅, 等.中國城市成人社區獲得性肺炎665例病原學多中心調查.中華結核和呼吸雜志, 2006, 29:3-8.
7.	Matsushima T, Miyashita N, File TM Jr. Etiology and management of community-acquired pneumonia in Asia. Curr Opin Infect Dis, 2002, 15:157-162.
8.	林榜素, 莊劍平, 胡容, 等.高齡社區獲得性肺炎的細菌學及其耐藥性研究.中國全科醫學, 2012, 15:1523-1525.
9.	劉又寧, 曹彬, 王輝, 等.中國九城市成人醫院獲得性肺炎微生物學與臨床特點調查.中華結核和呼吸雜志, 2012, 35:739-746.
10.	孫志泉.高齡社區獲得性肺炎的細菌學及藥敏分析.臨床肺科雜志, 2013, 18:1796-1797.
11.	朱仲生, 姜春玲, 張衛星, 等. 52例重癥社區獲得性肺炎病原體及藥物敏感性分析.中國社會醫學雜志, 2006, 23:169-170.
12.	Brown RB. Legionella pneumonia:the spectrum continues to expand. Chest, 2004, 125:1979-1980.
13.	Boukadida J, Salem N, Hannachi N, et al. Genotypic exploration of a hospital neonatal outbreak due to Klebsiella pneumonia producing extended-spectrum-betalactamase. Arch Pediatr, 2002, 9:463-468.
14.	Fine MJ, Auhle TE, Yealy DM, et al. A prediction rule to identify low-risk patients with community-acquired pneumonia.N Engl J Med, 1997, 336:243-250.
15.	李佩章, 陳艷華, 陸一平, 等.腫瘤患者醫院感染的病原菌分布及耐藥性分析.中華醫院感染學雜志, 2008, 12:1764-1766.

1. 查日田.重癥社區獲得性肺炎評價的研究進展.臨床肺科雜志, 2012, 17:2266-2268.
2. Houck PM, Bratzler DW, Nsa W, et al. Timing of antibiotic administration and outcomes for Medicare patients hospitalized with community-acquired pneumonia. Arch Intern Med, 2004, 164:637-644.
3. 中華醫學會呼吸病學分會.社區獲得性肺炎診斷及治療方案.中華結核和呼吸雜志, 2006, 29:651-655.
4. 葛均波, 徐永健, 主編.內科學.北京:人民衛生出版社, 2013, 9.
5. Schaaf B, Kruse J, Rupp J, et al. Sepsis severity predicts outcome in community-acquired pneumococcal pneumonia. Eur Respir J, 2007, 30:517-524.
6. 劉又寧, 陳民鈞, 趙鐵梅, 等.中國城市成人社區獲得性肺炎665例病原學多中心調查.中華結核和呼吸雜志, 2006, 29:3-8.
7. Matsushima T, Miyashita N, File TM Jr. Etiology and management of community-acquired pneumonia in Asia. Curr Opin Infect Dis, 2002, 15:157-162.
8. 林榜素, 莊劍平, 胡容, 等.高齡社區獲得性肺炎的細菌學及其耐藥性研究.中國全科醫學, 2012, 15:1523-1525.
9. 劉又寧, 曹彬, 王輝, 等.中國九城市成人醫院獲得性肺炎微生物學與臨床特點調查.中華結核和呼吸雜志, 2012, 35:739-746.
10. 孫志泉.高齡社區獲得性肺炎的細菌學及藥敏分析.臨床肺科雜志, 2013, 18:1796-1797.
11. 朱仲生, 姜春玲, 張衛星, 等. 52例重癥社區獲得性肺炎病原體及藥物敏感性分析.中國社會醫學雜志, 2006, 23:169-170.
12. Brown RB. Legionella pneumonia:the spectrum continues to expand. Chest, 2004, 125:1979-1980.
13. Boukadida J, Salem N, Hannachi N, et al. Genotypic exploration of a hospital neonatal outbreak due to Klebsiella pneumonia producing extended-spectrum-betalactamase. Arch Pediatr, 2002, 9:463-468.
14. Fine MJ, Auhle TE, Yealy DM, et al. A prediction rule to identify low-risk patients with community-acquired pneumonia.N Engl J Med, 1997, 336:243-250.
15. 李佩章, 陳艷華, 陸一平, 等.腫瘤患者醫院感染的病原菌分布及耐藥性分析.中華醫院感染學雜志, 2008, 12:1764-1766.

Chinese Journal of Respiratory and Critical Care Medicine

The Etiology Study on Severe Community-Acquired Pneumonia in Adults in Emergency Department

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content