Research progress of the duodenal-jejunal bypass liner in endoscopic bariatric surgery_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Authors：

WU Shihao , KONG Jianqiao , DAI Yang , HAN Xiaole , WANG Jun ,  DING Zhenghua

Department of General Surgery, Xiangyang No.1 People’s Hospital, Hubei University of Medicine, Xiangyang 441000, Hubei, P. R. China;

Corresponding?author：

DING Zhenghua, Email: 1357256337@qq.com

Keywords：

gastric diversion stent system; duodenal-jejunal bypass liner; endoscopic bariatric surgery; obesity

DOI：

10.7507/1007-9424.202606001

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Objective To investigate the mechanisms of action, clinical efficacy, safety, and current applications of the duodenal-jejunal bypass liner (DJBL) in endoscopic bariatric treatment, and to provide references for treatment decision-making in patients with obesity. Methods The relevant literature on DJBL in recent years was summarized. Results Weight-loss and metabolic benefits of DJBL may be associated with isolation of the proximal small intestinal mucosa, changes of incretin secretion, bile acid metabolism, and gut microbiota. DJBL shows certain effects on weight reduction and glycemic improvement during the implantation period, however its efficacy is influenced by device type, implantation duration, and study population. Clinical studies of domestic gastric diversion stent systems have also demonstrated short-term weight-loss effects. Main limitations of DJBL include device migration, gastrointestinal intolerance, liver abscess, and insufficient maintenance of therapeutic effects after device removal. Conclusions As a reversible endoscopic bariatric technology, DJBL provides a potential treatment option for selected patients who are unwilling or unsuitable for surgical bariatric procedures. Further multicenter, long-term clinical studies are required to define the suitable crowd and to evaluate its long-term benefits and risk management strategies.

Citation： WU Shihao, KONG Jianqiao, DAI Yang, HAN Xiaole, WANG Jun, DING Zhenghua. Research progress of the duodenal-jejunal bypass liner in endoscopic bariatric surgery. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2026, 33(9): 1280-1287. doi: 10.7507/1007-9424.202606001 Copy

1.
2.
3.
4.	機械工業儀器儀表綜合技術經濟研究所, 中國醫學裝備協會零部件分會. 中國醫療裝備及關鍵零部件技術發展報告 [M]. 北京: 機械工業出版社, 2024.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.	荀林娟, 陳亞梅, 王誼, 等. 內鏡下胃轉流支架系統治療肥胖的療效和安全性分析 [C]. 第六屆上海國際護理大會論文匯編 (下) , 2024.
26.
27.
28.
29.
30.
31.
32.
33.
34.
35.

1.
2.
3.
4. 機械工業儀器儀表綜合技術經濟研究所, 中國醫學裝備協會零部件分會. 中國醫療裝備及關鍵零部件技術發展報告 [M]. 北京: 機械工業出版社, 2024.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25. 荀林娟, 陳亞梅, 王誼, 等. 內鏡下胃轉流支架系統治療肥胖的療效和安全性分析 [C]. 第六屆上海國際護理大會論文匯編 (下) , 2024.
26.
27.
28.
29.
30.
31.
32.
33.
34.
35.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Research progress of the duodenal-jejunal bypass liner in endoscopic bariatric surgery

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content