Analysis of surgical intervention patterns for newly diagnosed colorectal cancer: a population-based study in Sichuan Province, 2020–2023_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Authors：

WANG Liya ¹ , TAN Kun ² , SHEN Minghui ² ,  WANG Xiaodong ¹

1. Division of Gastrointestinal Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu 610041, P. R. China;
2. Health Information Center of Sichuan Province, Chengdu 610041, P. R. China;

Corresponding?author：

WANG Xiaodong, Email: wangxiaodong@wchscu.cn

Keywords：

colorectal cancer; surgical intervention pattern; surgery rate; Sichuan Province

DOI：

10.7507/1007-9424.202506137

Video：

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Objective To analyze the surgical treatment characteristics for newly diagnosed colorectal cancer (CRC) patients based on hospital registry data in Sichuan Province. Methods Based on the hospitalization records of CRC inpatients from all secondary and tertiary hospitals in Sichuan Province (2015–2024), the newly diagnosed CRC patients admitted during 2020–2023 were identified and the rates of primary lesion resection, neostomy, and stoma reversal procedures were evaluated. Then stratified analyses by gender, age, tumor location, and organ metastasis at diagnosis were analyzed. The statistical significance was defined as one-sided test with α=0.025. Results A total of 118 787 newly diagnosed CRC inpatients in Sichuan Province (2020–2023) were enrolled, the cohort had a mean age of (66.4±12.3) years, with 70 756 (59.6%) males, 64 646 (54.4%) rectal cancer cases, and 16 418 (13.8%) cases exhibiting synchronous organ metastasis at diagnosis. Within one year post-diagnosis, 84 634 (71.2%) patients underwent primary lesion resection and 26 514 (22.3%) received neostomy procedures, both demonstrating significantly increasing annual trends (χ²_trend=72.2, P<0.001; χ²_trend=70.6, P<0.001) while showing inverse correlations with advancing age (χ²_trend=4 096.0, P<0.001; χ²_trend=56.3, P<0.001). Stratified analyses revealed significantly lower primary lesion resection rates among females vs. males, rectal cancer vs. colon cancer, and organ metastasis vs. non-organ metastasis patients (all P<0.001), whereas neostomy rates were higher in females and rectal cancer patients but lower in organ metastasis cases (all P<0.001). Among 26 514 neostomy patients, 11 288 (42.6%) underwent stoma reversal after a median (interquartile range) interval of 123 (95, 188) d, with 8 187 reversals (72.5%) within 6 months, 2 700 (23.9%) during 6–12 months, and 401 (3.6%) after 12 months. Reversal rates increased temporally (χ²_trend=80.0, P<0.001) but decreased with advancing age (χ²_trend=1 072.3, P<0.001). Conclusion In Sichuan Province, rising trends are observed in the hospitalization burdern of newly diagnosed CRC and rates of primary lesion resection, neostomy, and reversal.

Citation： WANG Liya, TAN Kun, SHEN Minghui, WANG Xiaodong. Analysis of surgical intervention patterns for newly diagnosed colorectal cancer: a population-based study in Sichuan Province, 2020–2023. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2025, 32(8): 991-997. doi: 10.7507/1007-9424.202506137 Copy

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10.	李琳, 李旭, 譚坤, 等. 中美結直腸癌流行病學現狀及趨勢. 中國普外基礎與臨床雜志, 2025, 32(6): 694-701.
11.	Siegel RL, Kratzer TB, Giaquinto AN, et al. Cancer statistics, 2025. CA Cancer J Clin, 2025, 75(1): 10-45.
12.	Bray F, Laversanne M, Sung H, et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin, 2024, 74(3): 229-263.
13.	秦敏曄, 王曉飛, 邱晶, 等. 2008–2020年江蘇省張家港市結腸癌發病趨勢及發病年齡變化特征分析. 中國慢性病預防與控制, 2025, 33(2): 98-103.
14.	田傳鑫, 趙磊. 結直腸癌及結直腸癌肝轉移流行病學特點. 中華腫瘤防治雜志, 2021, 28(13): 1033-1038.
15.	梁鋅, 劉夢雯, 張麗, 等. 全球部分地區肺癌發病趨勢及年齡變化情況分析. 中國腫瘤, 2022, 31(9): 683-692.
16.	劉瀟霞, 喬良, 羅玉英, 等. 2018年四川省以醫院登記為基礎的惡性腫瘤發病情況分析. 中國腫瘤, 2021, 30(6): 429-436.
17.	包凱芳, 陳潔平, 王思嘉, 等. 基于區域信息平臺的寧波市2011–2022年結直腸癌發病趨勢及年齡-時期-隊列分析. 中華腫瘤防治雜志, 2025, 32(9): 553-561.

1. Han B, Zheng R, Zeng H, et al. Cancer incidence and mortality in China, 2022. J Natl Cancer Cent, 2024, 4(1): 47-53.
2. 國家衛生健康委員會醫政司, 中華醫學會腫瘤學分會. 國家衛生健康委員會中國結直腸癌診療規范(2023版). 中華胃腸外科雜志, 2023, 26(6): 505-528.
3. 黃雷, 董秋石, 武愛文. 2024年度結直腸癌治療研究進展. 腫瘤綜合治療電子雜志, 2025, 11(2): 31-43.
4. 彭義煒, 葉霖. 結直腸癌外科治療的現狀和展望. 中外醫藥研究, 2024, 3(18): 162-164.
5. 李易津, 李俊. 腸癌肝轉移外科治療的國際進展. 肝膽外科雜志, 2024, 32(3): 230-236.
6. 四川省衛生健康委員會. 四川省衛生健康統計調查制度. 成都: 四川省衛生健康委員會, 2012.
7. 段占祺, 高嵐嵐, 楊珣, 等. 住院病案首頁質量考評平臺的設計與應用. 中國衛生質量管理, 2020, 27(3): 40-42.
8. 譚坤, 王利亞, 周德嘉, 等. 2015–2019年四川省結直腸癌住院負擔分析: 一項以人群為基礎的研究. 中國普外基礎與臨床雜志, 2021, 28(12): 1559-1564.
9. Qiu H, Wang L, Zhou L, et al. Comorbidity patterns in patients newly diagnosed with colorectal cancer: network-based study. JMIR Public Health Surveill, 2023, 9: e41999. doi: 10.2196/41999.
10. 李琳, 李旭, 譚坤, 等. 中美結直腸癌流行病學現狀及趨勢. 中國普外基礎與臨床雜志, 2025, 32(6): 694-701.
11. Siegel RL, Kratzer TB, Giaquinto AN, et al. Cancer statistics, 2025. CA Cancer J Clin, 2025, 75(1): 10-45.
12. Bray F, Laversanne M, Sung H, et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin, 2024, 74(3): 229-263.
13. 秦敏曄, 王曉飛, 邱晶, 等. 2008–2020年江蘇省張家港市結腸癌發病趨勢及發病年齡變化特征分析. 中國慢性病預防與控制, 2025, 33(2): 98-103.
14. 田傳鑫, 趙磊. 結直腸癌及結直腸癌肝轉移流行病學特點. 中華腫瘤防治雜志, 2021, 28(13): 1033-1038.
15. 梁鋅, 劉夢雯, 張麗, 等. 全球部分地區肺癌發病趨勢及年齡變化情況分析. 中國腫瘤, 2022, 31(9): 683-692.
16. 劉瀟霞, 喬良, 羅玉英, 等. 2018年四川省以醫院登記為基礎的惡性腫瘤發病情況分析. 中國腫瘤, 2021, 30(6): 429-436.
17. 包凱芳, 陳潔平, 王思嘉, 等. 基于區域信息平臺的寧波市2011–2022年結直腸癌發病趨勢及年齡-時期-隊列分析. 中華腫瘤防治雜志, 2025, 32(9): 553-561.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Analysis of surgical intervention patterns for newly diagnosed colorectal cancer: a population-based study in Sichuan Province, 2020–2023

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