YANG Hongzhao 1,2 , LIU Chang 1,3 , JIANG Hanyu 4 , YANG Yu 5 , ZHOU Jitao 5 , XIE Kunlin 1,2 , YANG Jiayin 1,2 , WU Hong 1,2
  • 1. Department of General Surgery, West China Hospital, Sichuan University, Chengdu 610041, P. R. China;
  • 2. Liver Transplant Center, Transplant Center, West China Hospital, Sichuan University, Chengdu 610041, P. R. China;
  • 3. Division of Liver Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu 610041, P. R. China;
  • 4. Department of Radiology, West China Hospital, Sichuan University, Chengdu 610041, P. R. China;
  • 5. Division of Abdominal Tumor Multimodality Treatment, Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, P. R. China;
WU Hong, Email: wuhong@scu.edu.cn
hepatocellular carcinoma; liver transplantation; whole process management; multidisciplinary team
10.7507/1007-9424.202301036
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Objective To summarize the experience of the whole process management of hepatocellular carcinoma (HCC) patients with high-risk of recurrence and metastasis based on the multidisciplinary team (MDT) mode, and to improve the clinicians’ understanding of the concept of whole process management, so as to improve the survival rate of patients with HCC. Method The clinicopathologic data of a HCC patient with high-risk of recurrence and metastasis admitted to the Division of Liver Surgery, Department of General Surgery, West China Hospital of Sichuan University were retrospectively analyzed. Results A 52-year-old male patient was diagnosed with HCC with intrahepatic metastasis (China liver cancer staging Ⅱ b, Barcelona Clinic Liver Cancer stage B) after admission due to “epigastric discomfort for 1+-month and liver occupying for 1+-week”. Through discussion by the MDT mode, the allogeneic liver transplantation was performed after successful downstaging following two conversion therapies. No serious complications occurred after operation, and the patient was discharged on the 23rd day after operation. Up to now, pulmonary bacterial and fungal infections and pulmonary metastases had been found during the postoperative follow-up. After anti-infective therapy and targeted therapy combined with radiotherapy, the patient was significantly relieved, had survived for 34 months after operation, and was still under regular follow-up. Conclusions For HCC patients with high-risk of recurrence and metastasis, MDT mode has a good clinical benefit for the whole process management of patient. Through the MDT model, the diagnosis, treatment, and follow-up of HCC are organically integrated, and the patient’ s diagnosis and treatment plans are dynamically adjusted to realize the whole process management of HCC patient, and to raise the survival rate and improve quality of life of HCC patient.

Citation： YANG Hongzhao, LIU Chang, JIANG Hanyu, YANG Yu, ZHOU Jitao, XIE Kunlin, YANG Jiayin, WU Hong. Whole process management of hepatocellular carcinoma patients with high-risk of recurrence and metastasis based on multidisciplinary team mode. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2023, 30(6): 653-659. doi: 10.7507/1007-9424.202301036 Copy

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