The management of a patient with primary pancreatic diffuse large B-cell lymphoma by muti-disciplinary term_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Authors：

YANG Fan ¹ , FENG Huaguo ² ,  GONG Jianping ²

1. Department of General Surgery, People’s Hospital of Chishui, Chishui, Guizhou 564700, P. R. China;
2. Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, P. R. China;

Corresponding?author：

GONG Jianping, Email: gongjianping11@126.com

Keywords：

primary pancreatic diffuse large B-cell lymphoma; muti-disciplinary term

DOI：

10.7507/1007-9424.201901068

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Objective To summarize the individualized diagnosis and treatment experience in a patient with primary pancreatic diffuse large B-cell lymphoma.Methods By muti-disciplinary term (MDT) model, a patient with primary pancreatic diffuse large B-cell lymphoma admitted in the People’s Hospital of Chishui in Dec. 2016 was discussed. The diagnosis, perioperative period management, and operation scheme were carried out by the MDT.Results The patient’s general condition was good. After multidisciplinary discussion in the Department of Radiology, Oncology, Interventional, and Hepatobiliary and Pancreatic Surgery, the patient was considered to have surgical indications. After thorough communication with the patient and family, the patient was selected for surgical resection. The whole operation lasted for 5 hours, and the intraoperative blood loss was about 300 mL. The operation was successfully completed and no complications such as pancreatic fistula occurred after operation. Liquid drainage tube was drawn out at 10 days after opertion, and pancreatic tube stent and T tube were retained. The patient discharged on 13 days after surgery. Subsequently, the patient underwent adjuvant chemotherapy. At present, the patient has been followed up for 1 year, no signs of tumor recurrence and metastasis, and continued follow-up.Conclusions Primary pancreatic diffuse large B-cell lymphoma is rare and has a poor prognosis. The main treatment is mutli-mode treatment based on surgical resection combined with chemotherapy.

Citation： YANG Fan, FENG Huaguo, GONG Jianping. The management of a patient with primary pancreatic diffuse large B-cell lymphoma by muti-disciplinary term. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2019, 26(6): 723-727. doi: 10.7507/1007-9424.201901068 Copy

1.	王木森, 王新國, 鄭金鋒, 等. 原發性肝臟彌漫大B細胞淋巴瘤5例并文獻復習. 重慶醫科大學學報, 2016, 41(6): 605-608.
2.	王永超, 李強. 原發性胰腺淋巴瘤的臨床分析及胰腺癌的鑒別. 中國腫瘤臨床, 2014, 41(2): 113-116.
3.	曾紀權, 鄭智, 王曉, 等. 原發胰腺淋巴瘤1例. 實用醫學雜志, 2013, 29(1): 165-166.
4.	Behrns KE, Sarr MG, Strickler JG. Pancreatic lymphoma: is it a surgical disease? Pancreas, 1994, 9(5): 662-667.
5.	陳康, 陳家飛, 黃浩釗, 等. 原發性胰腺淋巴瘤CT特征及增強特點. 局解手術學雜志, 2016, 25(12): 905-908.
6.	李慶東, 余維倩, 鄧和軍, 等. 2例罕見的原發性胰腺淋巴瘤. 檢驗醫學與臨床, 2013, 10(19): 2640-2641.
7.	Fujinaga Y, Lall C, Patel A, et al. MR features of primary and secondary malignant lymphoma of the pancreas: a pictorial review. Insights Imaging, 2013, 4(3): 321-329.
8.	周建軍, 丁建國, 周康榮, 等. 結外淋巴瘤: 影像學共性特征與病理的關系. 臨床放射學雜志, 2007, 26(6): 618-622.
9.	王運韜, 陳韻彬, 陳英, 等. 原發性胰腺淋巴瘤的MSCT影像表現分析. 臨床放射學雜志, 2015, 34(6): 924-928.
10.	Salvatore JR, Cooper B, Shah I, et al. Primary pancreatic lymphoma: a case report, literature review, and proposal for nomenclature. Med Oncol, 2000, 17(3): 237-247.
11.	Du X, Zhao Y, Zhang T, et al. Primary pancreatic lymphoma: a clinical quandary of diagnosis and treatment. Pancreas, 2011, 40(1): 30-36.
12.	姜鵬, 江勇, 吳寶強, 等. 原發性胰腺淋巴瘤診療體會. 臨床肝膽病雜志, 2011, 27(11): 1190-1192.
13.	Arcari A, Anselmi E, Bernuzzi P, et al. Primary pancreatic lymphoma. A report of five cases. Haematologica, 2005, 90(1): ECR09.
14.	肖夢加, 歐陽取長, 胡哲煜, 等. 循環腫瘤DNA在晚期乳腺癌的臨床應用進展. 臨床腫瘤學雜志, 2018, 24(9): 855-860.
15.	李龐, 崔凱, 李朝華, 等. 原發性胰腺彌漫性大B細胞淋巴瘤2例報告. 世界華人消化雜志, 2017, 20(3): 303-306.
16.	謝家泰, 傅鴻亮, 曾志榮, 等. 原發性胰腺淋巴瘤26例診療分析. 海南醫學, 2017, 14(1): 134-135.
17.	Rossi ED, Larghi A, Verna EC, et al. Endoscopic ultrasound-guided fine-needle aspiration with liquid-based cytologic preparation in the diagnosis of primary pancreatic lymphoma. Pancreas, 2010, 39(8): 1299-1302.
18.	Tuchek JM, De Jong SA, Pickleman J. Diagnosis, surgical intervention, and prognosis of primary pancreatic lymphoma. Am Surg, 1993, 59(8): 513-518.
19.	王艷芝, 楊云生, 蔡逢春, 等. 原發性胰腺淋巴瘤1例. 胃腸病學和肝病學雜志, 2013, 22(6): 591-592.
20.	徐梅梅, 高福來, 李莉, 等. 自身免疫性胰腺炎二例報道并文獻分析. 中國全科醫學, 2013, 16(29): 2760-2762.
21.	Hamano H, Kawa S, Horiuchi A, et al. High serum IgG4 concentrations in patients with sclerosing pancreatitis. N Engl J Med, 2001, 344(10): 732-738.
22.	鄧曉, 邱莎莎, 楊慶春. 原發性胰腺淋巴瘤診治分析: 附2例報告. 中國普通外科雜志, 2011, 20(3): 314-316.
23.	鄭天穎, 黃子星, 宋彬. 胰腺血液系統惡性腫瘤的影像學表現. 中國普外基礎與臨床雜志, 2017, 24(11): 1394-1399.
24.	何天霖, 胡先貴, 劉瑞, 等. 原發性胰腺淋巴瘤的診斷和治療(附9例報告). 第二軍醫大學學報, 2005, 26(8): 875-876.

1. 王木森, 王新國, 鄭金鋒, 等. 原發性肝臟彌漫大B細胞淋巴瘤5例并文獻復習. 重慶醫科大學學報, 2016, 41(6): 605-608.
2. 王永超, 李強. 原發性胰腺淋巴瘤的臨床分析及胰腺癌的鑒別. 中國腫瘤臨床, 2014, 41(2): 113-116.
3. 曾紀權, 鄭智, 王曉, 等. 原發胰腺淋巴瘤1例. 實用醫學雜志, 2013, 29(1): 165-166.
4. Behrns KE, Sarr MG, Strickler JG. Pancreatic lymphoma: is it a surgical disease? Pancreas, 1994, 9(5): 662-667.
5. 陳康, 陳家飛, 黃浩釗, 等. 原發性胰腺淋巴瘤CT特征及增強特點. 局解手術學雜志, 2016, 25(12): 905-908.
6. 李慶東, 余維倩, 鄧和軍, 等. 2例罕見的原發性胰腺淋巴瘤. 檢驗醫學與臨床, 2013, 10(19): 2640-2641.
7. Fujinaga Y, Lall C, Patel A, et al. MR features of primary and secondary malignant lymphoma of the pancreas: a pictorial review. Insights Imaging, 2013, 4(3): 321-329.
8. 周建軍, 丁建國, 周康榮, 等. 結外淋巴瘤: 影像學共性特征與病理的關系. 臨床放射學雜志, 2007, 26(6): 618-622.
9. 王運韜, 陳韻彬, 陳英, 等. 原發性胰腺淋巴瘤的MSCT影像表現分析. 臨床放射學雜志, 2015, 34(6): 924-928.
10. Salvatore JR, Cooper B, Shah I, et al. Primary pancreatic lymphoma: a case report, literature review, and proposal for nomenclature. Med Oncol, 2000, 17(3): 237-247.
11. Du X, Zhao Y, Zhang T, et al. Primary pancreatic lymphoma: a clinical quandary of diagnosis and treatment. Pancreas, 2011, 40(1): 30-36.
12. 姜鵬, 江勇, 吳寶強, 等. 原發性胰腺淋巴瘤診療體會. 臨床肝膽病雜志, 2011, 27(11): 1190-1192.
13. Arcari A, Anselmi E, Bernuzzi P, et al. Primary pancreatic lymphoma. A report of five cases. Haematologica, 2005, 90(1): ECR09.
14. 肖夢加, 歐陽取長, 胡哲煜, 等. 循環腫瘤DNA在晚期乳腺癌的臨床應用進展. 臨床腫瘤學雜志, 2018, 24(9): 855-860.
15. 李龐, 崔凱, 李朝華, 等. 原發性胰腺彌漫性大B細胞淋巴瘤2例報告. 世界華人消化雜志, 2017, 20(3): 303-306.
16. 謝家泰, 傅鴻亮, 曾志榮, 等. 原發性胰腺淋巴瘤26例診療分析. 海南醫學, 2017, 14(1): 134-135.
17. Rossi ED, Larghi A, Verna EC, et al. Endoscopic ultrasound-guided fine-needle aspiration with liquid-based cytologic preparation in the diagnosis of primary pancreatic lymphoma. Pancreas, 2010, 39(8): 1299-1302.
18. Tuchek JM, De Jong SA, Pickleman J. Diagnosis, surgical intervention, and prognosis of primary pancreatic lymphoma. Am Surg, 1993, 59(8): 513-518.
19. 王艷芝, 楊云生, 蔡逢春, 等. 原發性胰腺淋巴瘤1例. 胃腸病學和肝病學雜志, 2013, 22(6): 591-592.
20. 徐梅梅, 高福來, 李莉, 等. 自身免疫性胰腺炎二例報道并文獻分析. 中國全科醫學, 2013, 16(29): 2760-2762.
21. Hamano H, Kawa S, Horiuchi A, et al. High serum IgG4 concentrations in patients with sclerosing pancreatitis. N Engl J Med, 2001, 344(10): 732-738.
22. 鄧曉, 邱莎莎, 楊慶春. 原發性胰腺淋巴瘤診治分析: 附2例報告. 中國普通外科雜志, 2011, 20(3): 314-316.
23. 鄭天穎, 黃子星, 宋彬. 胰腺血液系統惡性腫瘤的影像學表現. 中國普外基礎與臨床雜志, 2017, 24(11): 1394-1399.
24. 何天霖, 胡先貴, 劉瑞, 等. 原發性胰腺淋巴瘤的診斷和治療(附9例報告). 第二軍醫大學學報, 2005, 26(8): 875-876.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

The management of a patient with primary pancreatic diffuse large B-cell lymphoma by muti-disciplinary term

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content