The correlative factors of palliation efficacy in malignant obstructive jaundice_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Authors：

GU Yuelei ,  YANG Sunhu , FAN Qiang , ZHANG Longlong

Department of General Surgery, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201999, P. R. China;

Corresponding?author：

YANG Sunhu, Email: yangsh06@126.com

Keywords：

malignant obstructive jaundice; palliation efficacy; influencing factor

DOI：

10.7507/1007-9424.201803043

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Objective To explore the influencing factors of palliation efficacy in malignant obstructive jaundice. Methods Clinical data of 107 patients with malignant obstructive jaundice who treated in Department of General Surgery, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, from March 2014 to December 2017, were retrospectively collected to analyze the influencing factors of palliation efficacy in 1 week and1 month after operation. Results Multivariate analysis results showed that, hilar obstruction and preoperative albumin level were influencing factors of palliation efficacy in 1 week after operation (P<0.05), patients with hepatic portal obstruction, and low preoperative albumin level had poor effect; hilar obstruction, preoperative albumin and total bilirubin level were influencing factors of palliation efficacy in 1 month after operation (P<0.05), patients with hepatic portal obstruction, low preoperative albumin level, and high total bilirubin level had poor effect. Conclusions The obstruction location, preoperative albumin level, and total bilirubin level are the independent influencing factors of palliation efficacy which played an important role in prognostic assessment.

Citation： GU Yuelei, YANG Sunhu, FAN Qiang, ZHANG Longlong. The correlative factors of palliation efficacy in malignant obstructive jaundice. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2018, 25(9): 1087-1093. doi: 10.7507/1007-9424.201803043 Copy

1.	徐川, 施海彬, 劉圣, 等. 肝門部膽管癌致梗阻性黃疸介入引流治療的預后分析. 介入放射學雜志, 2012, 21(9): 752-755.
2.	徐晨, 夏金堂, 徐波, 等. 惡性梗阻性黃疸術前減黃利弊的系統評價. 中華普通外科學文獻: 電子版, 2011, 5(1): 68-74.
3.	歐盛秋, 馬亦龍. 惡性梗阻性黃疸的治療現狀與進展. 中外醫療, 2014, 33(18): 197-198.
4.	Park S, Park JY, Chung MJ, et al. The efficacy of endoscopic palliation of obstructive jaundice in hepatocellular carcinoma. Yonsei Med J, 2014, 55(5): 1267-1272.
5.	Cho HC, Lee JK, Lee KH, et al. Are endoscopic or percutaneous biliary drainage effective for obstructive jaundice caused by hepatocellular carcinoma? Eur J Gastroenterol Hepatol, 2011, 23(3): 224-231.
6.	Lee JW, Han JK, Kim TK, et al. Obstructive jaundice in hepatocellular carcinoma: response after percutaneous transhepatic biliary drainage and prognostic factors. Cardiovasc Intervent Radiol, 2002, 25(3): 176-179.
7.	Günther RW, Schild H, Thelen M. Percutaneous transhepatic biliary drainage: experience with 311 procedures. Cardiovasc Intervent Radiol, 1988, 11(2): 65-71.
8.	Akiyama H, Okazaki T, Takashima I, et al. Percutaneous treatments for biliary diseases. Radiology, 1990, 176(1): 25-30.
9.	宋勇, 秦高平, 杜立學, 等. 膽道支架聯合PTCD對惡性梗阻性黃疸患者肝功能與生活質量的影響研究. 肝膽外科雜志, 2017, 25(2): 118-122.
10.	李臻, 李婭, 李騰飛, 等. 金屬膽道支架治療惡性梗阻性黃疸的臨床療效. 中華肝臟病雜志, 2012, 20(11): 843-847.
11.	Suh YG, Kim DY, Han KH, et al. Effective biliary drainage and proper treatment improve outcomes of hepatocellular carcinoma with obstructive jaundice. Gut Liver, 2014, 8(5): 526-535.
12.	胡冰, 周岱云, 龔彪, 等. 可膨式金屬膽道支架解除惡性膽管梗阻的臨床應用及其療效分析. 中華外科雜志, 1999, 37(5): 25-28.
13.	Carrasco CH, Zornoza J, Bechtel WJ. Malignant biliary obstruction: complications of percutaneous biliary drainage. Radiology, 1984, 152(2): 343-346.
14.	Baron TH. Palliation of malignant obstructive jaundice. Gastroenterol Clin North Am, 2006, 35(1): 101-112.
15.	Becker CD, Gl?ttli A, Maibach R, et al. Percutaneous palliation of malignant obstructive jaundice with the Wallstent endoprosthesis: follow-up and reintervention in patients with hiar and nonhilar obstruction. J Vasc Interv Radiol, 1993, 4(5): 597-604.
16.	Martin JA, Slivka A, Rabinovitz M, et al. ERCP and stent therapy for progressive jaundice in hepatocellular carcinoma: which patients benefit, which patients don’t? Dig Dis Sci, 1999, 44(7): 1298-1302.
17.	Matsueda K, Yamamoto H, Umeoka F, et al. Effectiveness of endoscopic biliary drainage for unresectable hepatocellular carcinoma associated with obstructive jaundice. J Gastroenterol, 2001, 36(3): 173-180.
18.	于平, 錢曉軍, 馬展鴻, 等. 惡性梗阻性黃疸合并膽系感染的臨床分析. 當代醫學: 中國介入放射學, 2008, 2(2): 155-157.
19.	Kordzaya DJ, Goderdzishvili VT. Bacterial translocation in obstructive jaundice in rats: role of mucosal lacteals. Eur J Surg, 2000, 166(5): 367-374.
20.	Tomioka M, Iinuma H, Okinaga K. Impaired Kupffer cell function and effect of immunotherapy in obstructive jaundice. J Surg Res, 2000, 92(2): 276-282.
21.	Hernández Guerrero A, Sánchez del Monte J, Sobrino Cossío S, et al. Prognostic factors of mortality in the malignant biliary obstruction unresectable after the insertion of an endoscopic stent. Rev Gastroenterol Mex, 2006, 71(1): 22-30.
22.	陳文超, 柳國勝. 單純光療或光療聯合白蛋白治療足月新生兒重度黃疸的效果分析. 中國病理生理雜志, 2015, 31(5): 943-946.
23.	Hosono S, Ohno T, Kimoto H, et al. Effects of albumin infusion therapy on total and unbound bilirubin values in term infants with intensive phototherapy. Pediatr Int, 2001, 43(1): 8-11.
24.	李維勤, 黎介壽, 全竹富, 等. 嚴重感染病人低白蛋白血癥的影響因素與臨床意義. 腸外與腸內營養, 2000, 7(4): 252.
25.	Vincent JL, Dubois MJ, Navickis RJ, et al. Hypoalbuminemia in acute illness: is there a rationale for intervention? A meta-analysis of cohort studies and controlled trials. Ann Surg, 2003, 237(3): 319-334.
26.	Jo JH, Park BH. Suprapapillary versus transpapillary stent placement for malignant biliary obstruction: which is better? J Vasc Interv Radiol, 2015, 26(4): 573-582.
27.	Huang X, Shen L, Jin Y, et al. Comparison of uncovered stent placement across versus above the main duodenal papilla for malignant biliary obstruction. J Vasc Interv Radiol, 2015, 26(3): 432-437.
28.	Lee SJ, Kim MD, Lee MS, et al. Comparison of the efficacy of covered versus uncovered metallic stents in treating inoperable malignant common bile duct obstruction: a randomized trial. J Vasc Interv Radiol, 2014, 25(12): 1912-1920.
29.	朱曉丹, 陳衛剛, 韓巖智, 等. 惡性梗阻性黃疸不同姑息治療方法療效觀察. 中國內鏡雜志, 2015, 21(4): 371-374.
30.	梁運嘯, 黃鵬宇, 農兵. 肝外膽管梗阻的支架治療研究進展. 世界華人消化雜志, 2017, 25(13): 1173-1178.
31.	翟仁友, 黃強. 惡性梗阻性黃疸介入治療常見問題的處理. 介入放射學雜志, 2007, 16(10): 649-651.
32.	黃可, 關文華, 韓焱, 等. 惡性梗阻性黃疸介入治療術后并發膽道感染的相關因素分析. 河南科技大學學報: 醫學版, 2014, 32(3): 177-179.
33.	王剛, 黎冶, 劉萬泉. 惡性梗阻性黃疸支架植入術后的近期并發癥分析. 中國醫藥指南, 2017, 15(1): 79-80.

1. 徐川, 施海彬, 劉圣, 等. 肝門部膽管癌致梗阻性黃疸介入引流治療的預后分析. 介入放射學雜志, 2012, 21(9): 752-755.
2. 徐晨, 夏金堂, 徐波, 等. 惡性梗阻性黃疸術前減黃利弊的系統評價. 中華普通外科學文獻: 電子版, 2011, 5(1): 68-74.
3. 歐盛秋, 馬亦龍. 惡性梗阻性黃疸的治療現狀與進展. 中外醫療, 2014, 33(18): 197-198.
4. Park S, Park JY, Chung MJ, et al. The efficacy of endoscopic palliation of obstructive jaundice in hepatocellular carcinoma. Yonsei Med J, 2014, 55(5): 1267-1272.
5. Cho HC, Lee JK, Lee KH, et al. Are endoscopic or percutaneous biliary drainage effective for obstructive jaundice caused by hepatocellular carcinoma? Eur J Gastroenterol Hepatol, 2011, 23(3): 224-231.
6. Lee JW, Han JK, Kim TK, et al. Obstructive jaundice in hepatocellular carcinoma: response after percutaneous transhepatic biliary drainage and prognostic factors. Cardiovasc Intervent Radiol, 2002, 25(3): 176-179.
7. Günther RW, Schild H, Thelen M. Percutaneous transhepatic biliary drainage: experience with 311 procedures. Cardiovasc Intervent Radiol, 1988, 11(2): 65-71.
8. Akiyama H, Okazaki T, Takashima I, et al. Percutaneous treatments for biliary diseases. Radiology, 1990, 176(1): 25-30.
9. 宋勇, 秦高平, 杜立學, 等. 膽道支架聯合PTCD對惡性梗阻性黃疸患者肝功能與生活質量的影響研究. 肝膽外科雜志, 2017, 25(2): 118-122.
10. 李臻, 李婭, 李騰飛, 等. 金屬膽道支架治療惡性梗阻性黃疸的臨床療效. 中華肝臟病雜志, 2012, 20(11): 843-847.
11. Suh YG, Kim DY, Han KH, et al. Effective biliary drainage and proper treatment improve outcomes of hepatocellular carcinoma with obstructive jaundice. Gut Liver, 2014, 8(5): 526-535.
12. 胡冰, 周岱云, 龔彪, 等. 可膨式金屬膽道支架解除惡性膽管梗阻的臨床應用及其療效分析. 中華外科雜志, 1999, 37(5): 25-28.
13. Carrasco CH, Zornoza J, Bechtel WJ. Malignant biliary obstruction: complications of percutaneous biliary drainage. Radiology, 1984, 152(2): 343-346.
14. Baron TH. Palliation of malignant obstructive jaundice. Gastroenterol Clin North Am, 2006, 35(1): 101-112.
15. Becker CD, Gl?ttli A, Maibach R, et al. Percutaneous palliation of malignant obstructive jaundice with the Wallstent endoprosthesis: follow-up and reintervention in patients with hiar and nonhilar obstruction. J Vasc Interv Radiol, 1993, 4(5): 597-604.
16. Martin JA, Slivka A, Rabinovitz M, et al. ERCP and stent therapy for progressive jaundice in hepatocellular carcinoma: which patients benefit, which patients don’t? Dig Dis Sci, 1999, 44(7): 1298-1302.
17. Matsueda K, Yamamoto H, Umeoka F, et al. Effectiveness of endoscopic biliary drainage for unresectable hepatocellular carcinoma associated with obstructive jaundice. J Gastroenterol, 2001, 36(3): 173-180.
18. 于平, 錢曉軍, 馬展鴻, 等. 惡性梗阻性黃疸合并膽系感染的臨床分析. 當代醫學: 中國介入放射學, 2008, 2(2): 155-157.
19. Kordzaya DJ, Goderdzishvili VT. Bacterial translocation in obstructive jaundice in rats: role of mucosal lacteals. Eur J Surg, 2000, 166(5): 367-374.
20. Tomioka M, Iinuma H, Okinaga K. Impaired Kupffer cell function and effect of immunotherapy in obstructive jaundice. J Surg Res, 2000, 92(2): 276-282.
21. Hernández Guerrero A, Sánchez del Monte J, Sobrino Cossío S, et al. Prognostic factors of mortality in the malignant biliary obstruction unresectable after the insertion of an endoscopic stent. Rev Gastroenterol Mex, 2006, 71(1): 22-30.
22. 陳文超, 柳國勝. 單純光療或光療聯合白蛋白治療足月新生兒重度黃疸的效果分析. 中國病理生理雜志, 2015, 31(5): 943-946.
23. Hosono S, Ohno T, Kimoto H, et al. Effects of albumin infusion therapy on total and unbound bilirubin values in term infants with intensive phototherapy. Pediatr Int, 2001, 43(1): 8-11.
24. 李維勤, 黎介壽, 全竹富, 等. 嚴重感染病人低白蛋白血癥的影響因素與臨床意義. 腸外與腸內營養, 2000, 7(4): 252.
25. Vincent JL, Dubois MJ, Navickis RJ, et al. Hypoalbuminemia in acute illness: is there a rationale for intervention? A meta-analysis of cohort studies and controlled trials. Ann Surg, 2003, 237(3): 319-334.
26. Jo JH, Park BH. Suprapapillary versus transpapillary stent placement for malignant biliary obstruction: which is better? J Vasc Interv Radiol, 2015, 26(4): 573-582.
27. Huang X, Shen L, Jin Y, et al. Comparison of uncovered stent placement across versus above the main duodenal papilla for malignant biliary obstruction. J Vasc Interv Radiol, 2015, 26(3): 432-437.
28. Lee SJ, Kim MD, Lee MS, et al. Comparison of the efficacy of covered versus uncovered metallic stents in treating inoperable malignant common bile duct obstruction: a randomized trial. J Vasc Interv Radiol, 2014, 25(12): 1912-1920.
29. 朱曉丹, 陳衛剛, 韓巖智, 等. 惡性梗阻性黃疸不同姑息治療方法療效觀察. 中國內鏡雜志, 2015, 21(4): 371-374.
30. 梁運嘯, 黃鵬宇, 農兵. 肝外膽管梗阻的支架治療研究進展. 世界華人消化雜志, 2017, 25(13): 1173-1178.
31. 翟仁友, 黃強. 惡性梗阻性黃疸介入治療常見問題的處理. 介入放射學雜志, 2007, 16(10): 649-651.
32. 黃可, 關文華, 韓焱, 等. 惡性梗阻性黃疸介入治療術后并發膽道感染的相關因素分析. 河南科技大學學報: 醫學版, 2014, 32(3): 177-179.
33. 王剛, 黎冶, 劉萬泉. 惡性梗阻性黃疸支架植入術后的近期并發癥分析. 中國醫藥指南, 2017, 15(1): 79-80.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

The correlative factors of palliation efficacy in malignant obstructive jaundice

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content