Transcatheter aortic valve replacement for aortic regurgitation complicated by Takayasu arteritis: A case report_Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Authors：

GAO Jianbin ¹ , LI Jian ² , YANG Yu ¹ , MA Mier ¹ , YANG Kairui ¹ , LUO Wei ¹ , WANG Ning ¹ , ZHU Da ¹ ,  OUYANG Wenbin ^1,3 , PAN Xiangbin ^1,3

1. Department of Structure Heart Center, Fuwai Yunnan Hospital, Chinese Academy of Medical Sciences, Affiliated Cardiovascular Hospital of Kunming Medical University, Kunming, 650032, P. R. China;
2. Ultrasound Department, Fuwai Yunnan Hospital, Chinese Academy of Medical Sciences, Affiliated Cardiovascular Hospital of Kunming Medical University, Kunming, 650032, P. R. China;
3. Department of Structural Heart Disease, National Center for Cardiovascular Disease, Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100037, P. R. China;

Corresponding?author：

OUYANG Wenbin, Email: droywb31@163.com

Keywords：

Takayasu arteritis; aortic regurgitation; transapical approach; transcatheter aortic valve replacement; case report

DOI：

10.7507/1007-4848.202409036

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Patients with Takayasu arteritis combined with aortic valve disease often have a poor prognosis following surgical valve replacement, frequently encountering complications such as perivalvular leakage, valve detachment, and anastomotic aneurysm. This article presents a high-risk case wherein severe aortic valve insufficiency associated with Takayasu arteritis was successfully managed through transcatheter aortic valve implantation via the transapical approach. The patient had satisfactory valve function with no complications observed during the six-month postoperative follow-up. This case provides a minimally invasive and feasible alternative for the clinical management of such high-risk patients.

Citation： GAO Jianbin, LI Jian, YANG Yu, MA Mier, YANG Kairui, LUO Wei, WANG Ning, ZHU Da, OUYANG Wenbin, PAN Xiangbin. Transcatheter aortic valve replacement for aortic regurgitation complicated by Takayasu arteritis: A case report. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2026, 33(1): 163-166. doi: 10.7507/1007-4848.202409036 Copy

1.	譚葳, 潘麗麗, 李濤濤, 等. 大動脈炎心臟瓣膜病變的研究進展. 中國醫藥, 2023, 18(9): 1414-1418.Tan W, Pan LL, Li TT, et al. Research progress of cardiac valve disease in Takayasu arteritis. China Med, 2023, 18(9): 1414-1418.
2.	Fath AR, Mookadam F, Aglan A, et al. Surgical management of aortic regurgitation in Takayasu's arteritis: a systematic review of techniques and outcomes. Perm J, 2022, 26(3): 103-113.
3.	Li C, Liu Y, Qi R, et al. Repair of aortic regurgitation due to Takayasu arteritis. Heart Surg Forum, 2013, 16(1): E24-E26.
4.	Matsuura K, Ogino H, Kobayashi J, et al. Surgical treatment of aortic regurgitation due to Takayasu arteritis: long-term morbidity and mortality. Circulation, 2005, 112(24): 3707-3712.
5.	Zhang Y, Fan P, Zhang H, et al. Surgical treatment in patients with aortic regurgitation due to Takayasu arteritis. Ann Thorac Surg, 2020, 110(1): 165-171.
6.	Cheng X, Li Z, Dang A, et al. Different treatment options for Takayasu arteritis patients with moderate-to-severe aortic regurgitation: long-term outcomes. Rheumatology (Oxford), 2021, 60(7): 3134-3143.
7.	Ning X, Wang W, Lu F, et al. Transapical transcatheter aortic valve implantation for aortic regurgitation in Takayasu arteritis. Heart Surg Forum, 2022, 25(5): E689-E691.
8.	Chen J, Lu Y, Yang Y, et al. Transcatheter aortic valve replacement for aortic regurgitation caused by Takayasu arteritis. Ann Thorac Surg, 2022, 114(2): e145-e148.
9.	Perera AH, Youngstein T, Gibbs RG, et al. Optimizing the outcome of vascular intervention for Takayasu arteritis. Br J Surg, 2014, 101(2): 43-50.
10.	Shi X, Du J, Li T, et al. Risk factors and surgical prognosis in patients with aortic valve involvement caused by Takayasu arteritis. Arthritis Res Ther, 2022, 24(1): 102.

1. 譚葳, 潘麗麗, 李濤濤, 等. 大動脈炎心臟瓣膜病變的研究進展. 中國醫藥, 2023, 18(9): 1414-1418.Tan W, Pan LL, Li TT, et al. Research progress of cardiac valve disease in Takayasu arteritis. China Med, 2023, 18(9): 1414-1418.
2. Fath AR, Mookadam F, Aglan A, et al. Surgical management of aortic regurgitation in Takayasu's arteritis: a systematic review of techniques and outcomes. Perm J, 2022, 26(3): 103-113.
3. Li C, Liu Y, Qi R, et al. Repair of aortic regurgitation due to Takayasu arteritis. Heart Surg Forum, 2013, 16(1): E24-E26.
4. Matsuura K, Ogino H, Kobayashi J, et al. Surgical treatment of aortic regurgitation due to Takayasu arteritis: long-term morbidity and mortality. Circulation, 2005, 112(24): 3707-3712.
5. Zhang Y, Fan P, Zhang H, et al. Surgical treatment in patients with aortic regurgitation due to Takayasu arteritis. Ann Thorac Surg, 2020, 110(1): 165-171.
6. Cheng X, Li Z, Dang A, et al. Different treatment options for Takayasu arteritis patients with moderate-to-severe aortic regurgitation: long-term outcomes. Rheumatology (Oxford), 2021, 60(7): 3134-3143.
7. Ning X, Wang W, Lu F, et al. Transapical transcatheter aortic valve implantation for aortic regurgitation in Takayasu arteritis. Heart Surg Forum, 2022, 25(5): E689-E691.
8. Chen J, Lu Y, Yang Y, et al. Transcatheter aortic valve replacement for aortic regurgitation caused by Takayasu arteritis. Ann Thorac Surg, 2022, 114(2): e145-e148.
9. Perera AH, Youngstein T, Gibbs RG, et al. Optimizing the outcome of vascular intervention for Takayasu arteritis. Br J Surg, 2014, 101(2): 43-50.
10. Shi X, Du J, Li T, et al. Risk factors and surgical prognosis in patients with aortic valve involvement caused by Takayasu arteritis. Arthritis Res Ther, 2022, 24(1): 102.

Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Transcatheter aortic valve replacement for aortic regurgitation complicated by Takayasu arteritis: A case report

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