Application of DynaCT combined with 3D iGuide puncture technique to microwave ablation of lung cancer_Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Authors：

FAN Chen , TANG Haohuan , ZHOU Qi , SUN Feihu , DING Wei , SUN Lei , WANG Weitao , XU Ping ,  WANG Weidong

Department of Intervention, Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, 214023, Jiangsu, P. R. China;

Corresponding?author：

WANG Weidong, Email: Wdoc@sina.com

Keywords：

DynaCT; lung cancer; microwave ablation; intervention therapy

DOI：

10.7507/1007-4848.202102052

Video：

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Objective To investigate the feasibility and safety of DynaCT microwave ablation (MWA) guided by 3D iGuide puncture technology for lung cancer.Methods The clinical data of 19 patients with primary or metastatic lung cancer who underwent DynaCT MWA from June 2019 to December 2020 in our hospital were retrospectively analyzed, including 15 males and 4 females with an average age of 64.9±11.7 years. The technical success rates, adverse reactions and complications, postoperative hospital stay, and local therapeutic efficacy were recorded.Results Technical success rate was 100.0%. The mean time required to target and place the needle was 15.7±3.7 min and the mean ablation time was 5.7±1.6 min. Thirteen patients underwent biopsy synchronously before the ablation, and 10 (76.9%) patients had positive pathological results. The main adverse reactions were pain (7/19, 36.8%), post-ablation syndrome (4/19, 21.1%) and cough (2/19, 10.5%). The minor complications were pneumothorax (6/19, 31.6%), hemorrhage (5/19, 26.3%), pleural effusion (2/19, 10.5%) and cavity (1/19, 5.3%). Three patients had moderate pneumothorax and received closed thoracic drainage. The median hospitalization time after ablation was 2.0 (2.0, 3.0) d, and no patient died during the perioperative period. The initial complete ablation rate was 89.5% (17 patients) and the incomplete ablation rate was 10.5% (2 patients) at 1-month follow-up, and no local progression was observed.Conclusion DynaCT MWA of lung cancer under the guidance of 3D iGuide system is safe and feasible with a high short-term local control rate, but the long-term efficacy remains to be further observed.

Citation： FAN Chen, TANG Haohuan, ZHOU Qi, SUN Feihu, DING Wei, SUN Lei, WANG Weitao, XU Ping, WANG Weidong. Application of DynaCT combined with 3D iGuide puncture technique to microwave ablation of lung cancer. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2023, 30(2): 221-225. doi: 10.7507/1007-4848.202102052 Copy

1.	鄒小農, 賈漫漫, 王鑫, 等. 《2020 全球癌癥報告》要點解讀. 中國胸心血管外科臨床雜志, 2021, 28(1): 11-18.
2.	中華醫學會, 中華醫學會腫瘤學分會, 華醫學會雜志社. 中華醫學會肺癌臨床診療指南(2019 版). 中華腫瘤雜志, 2020, 42(4): 257-258.
3.	Ye X, Fan W, Wang H, et al. Expert consensus workshop report: Guidelines for thermal ablation of primary and metastatic lung tumors (2018 edition). J Cancer Res Ther, 2018, 14(4): 730-744.
4.	Cazzato RL, Battistuzzi JB, Catena V, et al. Cone-beam computed tomography (CBCT) versus CT in lung ablation procedure: Which is faster? Cardiovasc Intervent Radiol, 2015, 38(5): 1231-1236.
5.	袁宏軍, 劉鳳永, 李鑫, 等. 3D iGuide 穿刺技術在 DynaCT 引導射頻消融治療大肝癌中的應用. 中華介入放射學電子雜志, 2018, 6(2): 113-117.
6.	曹碧輝, 陳德基, 梁寶霞, 等. 錐形束 CT 聯合 iGuide 引導系統在經皮經胸肺穿刺活檢術中的應用. 中國介入影像與治療學, 2018, 15(4): 213-216.
7.	Ahmed M, Solbiati L, Brace CL, et al. Image-guided tumor ablation: Standardization of terminology and reporting criteria—A 10-year update. Radiology, 2014, 273(1): 241-260.
8.	Howington JA, Blum MG, Chang AC, et al. Treatment of stageⅠandⅡnon-small cell lung cancer: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest, 2013, 143(5 Suppl): e278S-e313S.
9.	Gillams A. Ablation of lung tumours. Cancer Imaging, 2012, 12(2): 361-362.
10.	Lin M, Eiken P, Blackmon S. Image guided thermal ablation in lung cancer treatment. J Thorac Dis, 2020, 12(11): 7039-7047.
11.	Tafti BA, Genshaft S, Suh R, et al. Lung ablation: Indications and techniques. Semin Intervent Radiol, 2019, 36(3): 163-175.
12.	Abtin F, De Baere T, Dupuy DE, et al. Updates on current role and practice of lung ablation. J Thorac Imaging, 2019, 34(4): 266-277.
13.	Macchi M, Belfiore MP, Floridi C, et al. Radiofrequency versus microwave ablation for treatment of the lung tumours: LUMIRA (lung microwave radiofrequency) randomized trial. Med Oncol, 2017, 34(5): 96.
14.	Chi J, Ding M, Shi Y, et al. Comparison study of computed tomography-guided radiofrequency and microwave ablation for pulmonary tumors: A retrospective, case-controlled observational study. Thorac Cancer, 2018, 9(10): 1241-1248.
15.	Yuan Z, Wang Y, Zhang J, et al. A meta-analysis of clinical outcomes after radiofrequency ablation and microwave ablation for lung cancer and pulmonary metastases. J Am Coll Radiol, 2019, 16(3): 302-314.
16.	Prud'homme C, Deschamps F, Moulin B, et al. Image-guided lung metastasis ablation: A literature review. Int J Hyperthermia, 2019, 36(2): 37-45.
17.	Grasso RF, Cazzato RL, Luppi G, et al. Percutaneous lung biopsies: Performance of an optical CT-based navigation system with a low-dose protocol. Eur Radiol, 2013, 23(11): 3071-3076.
18.	Wang D, Li B, Bie Z, et al. Synchronous core-needle biopsy and microwave ablation for highly suspicious malignant pulmonary nodule via a coaxial cannula. J Cancer Res Ther, 2019, 15(7): 1484-1489.
19.	Rotolo N, Floridi C, Imperatori A, et al. Comparison of cone-beam CT-guided and CT fluoroscopy-guided transthoracic needle biopsy of lung nodules. Eur Radiol, 2016, 26(2): 381-389.

1. 鄒小農, 賈漫漫, 王鑫, 等. 《2020 全球癌癥報告》要點解讀. 中國胸心血管外科臨床雜志, 2021, 28(1): 11-18.
2. 中華醫學會, 中華醫學會腫瘤學分會, 華醫學會雜志社. 中華醫學會肺癌臨床診療指南(2019 版). 中華腫瘤雜志, 2020, 42(4): 257-258.
3. Ye X, Fan W, Wang H, et al. Expert consensus workshop report: Guidelines for thermal ablation of primary and metastatic lung tumors (2018 edition). J Cancer Res Ther, 2018, 14(4): 730-744.
4. Cazzato RL, Battistuzzi JB, Catena V, et al. Cone-beam computed tomography (CBCT) versus CT in lung ablation procedure: Which is faster? Cardiovasc Intervent Radiol, 2015, 38(5): 1231-1236.
5. 袁宏軍, 劉鳳永, 李鑫, 等. 3D iGuide 穿刺技術在 DynaCT 引導射頻消融治療大肝癌中的應用. 中華介入放射學電子雜志, 2018, 6(2): 113-117.
6. 曹碧輝, 陳德基, 梁寶霞, 等. 錐形束 CT 聯合 iGuide 引導系統在經皮經胸肺穿刺活檢術中的應用. 中國介入影像與治療學, 2018, 15(4): 213-216.
7. Ahmed M, Solbiati L, Brace CL, et al. Image-guided tumor ablation: Standardization of terminology and reporting criteria—A 10-year update. Radiology, 2014, 273(1): 241-260.
8. Howington JA, Blum MG, Chang AC, et al. Treatment of stageⅠandⅡnon-small cell lung cancer: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest, 2013, 143(5 Suppl): e278S-e313S.
9. Gillams A. Ablation of lung tumours. Cancer Imaging, 2012, 12(2): 361-362.
10. Lin M, Eiken P, Blackmon S. Image guided thermal ablation in lung cancer treatment. J Thorac Dis, 2020, 12(11): 7039-7047.
11. Tafti BA, Genshaft S, Suh R, et al. Lung ablation: Indications and techniques. Semin Intervent Radiol, 2019, 36(3): 163-175.
12. Abtin F, De Baere T, Dupuy DE, et al. Updates on current role and practice of lung ablation. J Thorac Imaging, 2019, 34(4): 266-277.
13. Macchi M, Belfiore MP, Floridi C, et al. Radiofrequency versus microwave ablation for treatment of the lung tumours: LUMIRA (lung microwave radiofrequency) randomized trial. Med Oncol, 2017, 34(5): 96.
14. Chi J, Ding M, Shi Y, et al. Comparison study of computed tomography-guided radiofrequency and microwave ablation for pulmonary tumors: A retrospective, case-controlled observational study. Thorac Cancer, 2018, 9(10): 1241-1248.
15. Yuan Z, Wang Y, Zhang J, et al. A meta-analysis of clinical outcomes after radiofrequency ablation and microwave ablation for lung cancer and pulmonary metastases. J Am Coll Radiol, 2019, 16(3): 302-314.
16. Prud'homme C, Deschamps F, Moulin B, et al. Image-guided lung metastasis ablation: A literature review. Int J Hyperthermia, 2019, 36(2): 37-45.
17. Grasso RF, Cazzato RL, Luppi G, et al. Percutaneous lung biopsies: Performance of an optical CT-based navigation system with a low-dose protocol. Eur Radiol, 2013, 23(11): 3071-3076.
18. Wang D, Li B, Bie Z, et al. Synchronous core-needle biopsy and microwave ablation for highly suspicious malignant pulmonary nodule via a coaxial cannula. J Cancer Res Ther, 2019, 15(7): 1484-1489.
19. Rotolo N, Floridi C, Imperatori A, et al. Comparison of cone-beam CT-guided and CT fluoroscopy-guided transthoracic needle biopsy of lung nodules. Eur Radiol, 2016, 26(2): 381-389.

Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Application of DynaCT combined with 3D iGuide puncture technique to microwave ablation of lung cancer

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