Clinical characteristics of 57 patients with early stage esophageal cancer or precancerosis treated with esophagectomy following endoscopic submucosal dissection_Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Authors：

SI Jicheng ¹ , HUANG Ben ¹ , LIU Haitao ¹ , YUANG Yong ² ,  CHEN Longqi ²

1. Department of Cardiothoracic Surgery, Shanxian Hygeia Hospital, Shanxian, 274300, Shandong, P.R.China;
2. Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, 610041, P.R.China;

Corresponding?author：

CHEN Longqi, Email: drchenlq@gmail.com

Keywords：

Early stage esophageal cancer; endoscopic submucosal dissection (ESD); esophagectomy

DOI：

10.7507/1007-4848.201612024

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Objective To analyze the clinical characteristics of patients treated with esophagectomy following endoscopic submucosal dissection (ESD) for early stage esophageal cancer or precancerosis and the reasons for esophagectomy. Methods We retrospectively analyzed the clinical data of 57 patients who were treated with esophagectomy following ESD in West China Hospital and Shanxian Hygeia Hospital from January 2012 through October 2016. There were 42 males and 15 females at age of 65.4 (52–77) years. There were 15 patients of upper thoracic lesions, the middle thoracic lesions in 34 patients, and the lower thoracic lesions in 8 patients. Results The reasons for esophagectomy included 3 patients with residual tumor, 8 patients with local recurrence, 37 patients with esophageal stricture, and 9 patients with dysphagia, although the diameter was larger than 1.0 cm. The pathology after esophagectomy revealed that tumor was found in 16 patients, including 3 patients with residual tumor and 8 with recurrent tumor confirmed before esophagectomy, and 5 patients with new-found recurrent tumor. Conclusion In the treatment of early stage esophageal cancer or precancerosis, the major reasons for esophagectomy following ESD include esophageal stricture, abnormal esophageal dynamics, local residual or recurrence.

Citation： SI Jicheng, HUANG Ben, LIU Haitao, YUANG Yong, CHEN Longqi. Clinical characteristics of 57 patients with early stage esophageal cancer or precancerosis treated with esophagectomy following endoscopic submucosal dissection. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2017, 24(10): 764-767. doi: 10.7507/1007-4848.201612024 Copy

1.	Smith I, Kahaleh M. Endoscopic versus surgical therapy for Barrett's esophagus neoplasia. Expert Rev Gastroenterol Hepatol, 2015, 9: 31-35.
2.	Pech O, Bollschweiler E, Manner H, et al. Comparison between endoscopic and surgical resection of mucosal esophageal adenocarcinoma in Barrett's esophagus at two high volume centers. Ann Surg, 2011, 254: 67-72.
3.	Tomizawa Y, Iyer PG, Wong Kee Song LM, et al. Safety of endoscopic mucosal resection for Barrett's esophagus. Am J Gastroenterol, 2013, 108: 1440-1447.
4.	Matsui N, Akahoshi K, Nakamura K, et al. Endoscopic submucosal dissection for removal of superficial gastrointestinal neoplasms: A technical review. World J Gastrointest Endosc, 2012, 4(4): 123-136.
5.	Maier A, Tomaselli F, Gebhard F, et al. Palliation of advanced esophageal carcinoma by photodyn amic therapy and irradiation. Ann Thorac Surg, 2000, 69(4): 1006-1009.
6.	Kothari S, Kaul V. Endoscopic mucosal resection and endoscopic submucosal dissection for endoscopic therapy of barrett's esophagus related neoplasia. Gastroenterol Clin North Am, 2015, 44: 317-335.
7.	周平紅, 蔡明琰, 姚禮慶. 消化道黏膜病變內鏡黏膜下剝離術的專家共識意見. 診斷學理論與實踐, 2012, 11(5): 531-535.0.
8.	劉莉, 史維. ESD術后并發癥及處置. 現代消化及介入診療, 2014, 19(4): 247-251.0.
9.	金海林, 韓樹堂, 肖軍, 等. 內鏡黏膜下剝離術治療早期食管癌及癌前病變44例. 世界華人消化雜志, 2015, 23(4): 608-612.0.
10.	Ono S, Fujishiro M, Niimi K, et al. Long-term outcomes of endoscopic submucosal dissection for superficial esophageal squamous cell neoplasms. Gastrointest Endosc, 2009, 70(5): 860-866.
11.	Ono S, Fujishiro M, Koike K. Endoscopic submucosal dissection for superficial esophageal neoplasms. World J Gastrointest Endosc, 2012, 4(5): 162-166.
12.	Fujishiro M, Yahagi N, Kakushima N, et al. Endoscopic submucosal dissection of esophageal squamous cell neoplasms. Clin Gastroenterol Hepatol, 2006, 4: 688-694.
13.	王瑾, 秦金玉, 郭天嬌, 等. 常規內鏡黏膜下剝離術與經內鏡黏膜下隧道剝離術治療食管大面積黏膜病變的療效及并發癥分析. 四川大學學報(醫學版), 2015, 46(6): 896-900.0.
14.	Ono S, FUjishiro M, Niimi K, et al. Predictors of postoperative stricture after esophageal endoscopic submucosal dissection for superficial spuamous cell neoplasms. Endoscopy, 2009, 41: 661-665.
15.	Malhi-Chowia N, Wolfsen HC, DeVault KR. Esophageal dysmotility in patients undergoing photodynamic therapy. Mayo Clin Proc, 2001,76(10): 987-989.
16.	Ota M, Ohki T, Nakamura T, et al. Investigation of ulcer healing after esophageal EMR/ESD. Esophagus, 2010, 7: 101-104.
17.	馬丹, 楊帆, 廖專, 等. 中國早期食管癌篩查及內鏡診治專家共識意見(2014年, 北京). 中國實用內科雜志, 2015, 35(4): 320-337.0.
18.	Joo DC, Kim GH, Park do Y, et al. Long-term outcome after endoscopic submucosal dissection in patients with superficial esophageal squamous cell carcinoma: a single-center study. Gut Liver, 2014, 8(6): 612-618.
19.	Hyatt BJ, Paull PE, Wassef W. Gastric oncology: an update. Curr Opin Gastroenterol, 2009, 25(6): 570-578．.

1. Smith I, Kahaleh M. Endoscopic versus surgical therapy for Barrett's esophagus neoplasia. Expert Rev Gastroenterol Hepatol, 2015, 9: 31-35.
2. Pech O, Bollschweiler E, Manner H, et al. Comparison between endoscopic and surgical resection of mucosal esophageal adenocarcinoma in Barrett's esophagus at two high volume centers. Ann Surg, 2011, 254: 67-72.
3. Tomizawa Y, Iyer PG, Wong Kee Song LM, et al. Safety of endoscopic mucosal resection for Barrett's esophagus. Am J Gastroenterol, 2013, 108: 1440-1447.
4. Matsui N, Akahoshi K, Nakamura K, et al. Endoscopic submucosal dissection for removal of superficial gastrointestinal neoplasms: A technical review. World J Gastrointest Endosc, 2012, 4(4): 123-136.
5. Maier A, Tomaselli F, Gebhard F, et al. Palliation of advanced esophageal carcinoma by photodyn amic therapy and irradiation. Ann Thorac Surg, 2000, 69(4): 1006-1009.
6. Kothari S, Kaul V. Endoscopic mucosal resection and endoscopic submucosal dissection for endoscopic therapy of barrett's esophagus related neoplasia. Gastroenterol Clin North Am, 2015, 44: 317-335.
7. 周平紅, 蔡明琰, 姚禮慶. 消化道黏膜病變內鏡黏膜下剝離術的專家共識意見. 診斷學理論與實踐, 2012, 11(5): 531-535.0.
8. 劉莉, 史維. ESD術后并發癥及處置. 現代消化及介入診療, 2014, 19(4): 247-251.0.
9. 金海林, 韓樹堂, 肖軍, 等. 內鏡黏膜下剝離術治療早期食管癌及癌前病變44例. 世界華人消化雜志, 2015, 23(4): 608-612.0.
10. Ono S, Fujishiro M, Niimi K, et al. Long-term outcomes of endoscopic submucosal dissection for superficial esophageal squamous cell neoplasms. Gastrointest Endosc, 2009, 70(5): 860-866.
11. Ono S, Fujishiro M, Koike K. Endoscopic submucosal dissection for superficial esophageal neoplasms. World J Gastrointest Endosc, 2012, 4(5): 162-166.
12. Fujishiro M, Yahagi N, Kakushima N, et al. Endoscopic submucosal dissection of esophageal squamous cell neoplasms. Clin Gastroenterol Hepatol, 2006, 4: 688-694.
13. 王瑾, 秦金玉, 郭天嬌, 等. 常規內鏡黏膜下剝離術與經內鏡黏膜下隧道剝離術治療食管大面積黏膜病變的療效及并發癥分析. 四川大學學報(醫學版), 2015, 46(6): 896-900.0.
14. Ono S, FUjishiro M, Niimi K, et al. Predictors of postoperative stricture after esophageal endoscopic submucosal dissection for superficial spuamous cell neoplasms. Endoscopy, 2009, 41: 661-665.
15. Malhi-Chowia N, Wolfsen HC, DeVault KR. Esophageal dysmotility in patients undergoing photodynamic therapy. Mayo Clin Proc, 2001,76(10): 987-989.
16. Ota M, Ohki T, Nakamura T, et al. Investigation of ulcer healing after esophageal EMR/ESD. Esophagus, 2010, 7: 101-104.
17. 馬丹, 楊帆, 廖專, 等. 中國早期食管癌篩查及內鏡診治專家共識意見(2014年, 北京). 中國實用內科雜志, 2015, 35(4): 320-337.0.
18. Joo DC, Kim GH, Park do Y, et al. Long-term outcome after endoscopic submucosal dissection in patients with superficial esophageal squamous cell carcinoma: a single-center study. Gut Liver, 2014, 8(6): 612-618.
19. Hyatt BJ, Paull PE, Wassef W. Gastric oncology: an update. Curr Opin Gastroenterol, 2009, 25(6): 570-578．.

Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Clinical characteristics of 57 patients with early stage esophageal cancer or precancerosis treated with esophagectomy following endoscopic submucosal dissection

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content