Biomechanical study of nickel-titanium three-dimensional memory alloy mesh and autologous bone in treatment of canine tibial plateau collapse fracture_Chinese Journal of Reparative and Reconstructive Surgery

Authors：

YAN Zhaokui , LIANG Yu ^Δ ,  FANG Yue , YAO Xiangyu , MA Kunlong , HUANG Fuguo

Department of Orthopedics, West China Hospital, Sichuan University, Chengdu Sichuan, 610041, P.R.China;

Corresponding?author：

FANG Yue, Email: fangyue1968@163.com

Keywords：

Nickel-titanium alloy; three-dimensional memory alloy mesh; tibial plateau fracture; biomechanics; dog

DOI：

10.7507/1002-1892.201709068

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

ObjectiveTo evaluate the biomechanical effect of a nickel-titanium (Ni-Ti) three-dimensional memory alloy mesh in treating a canine tibial plateau collapse fracture model and to lay a foundation for further experiments in vivo.MethodsSixteen tibial plateau specimens of 8 adult Beagle dogs were harvested. Twelve specimens were taken to prepare canine tibial plateau collapse fracture models (Schatzker type Ⅲ) and randomly divided into groups A, B, and C, with 4 specimens in each group. Four normal tibia specimens were used as blank control group (group D). In groups A and B, the bone defects were repaired with Ni-Ti three-dimensional shape memory alloy mesh combined with autologous bone and simple autologous bone respectively, and fixed with the lateral plate and screw. In group C, the bone defect was directly fixed with the lateral plate and screw. By using a biomechanical tester, a progressive load (0-1 700 N) was loaded vertically above the femoral condyle. The maximum failure load was recorded and the stiffness was calculated according to the load-displacement curve.ResultsThe maximum failure loads in groups A, B, C, and D were (1 624.72±7.02), (1 506.57±3.37), (1 102.00±1.83), and (1 767.64±24.56) N, respectively; and the stiffnesses were (129.72±20.83), (96.54±27.05), (74.96±17.70), and (169.01±35.62) N/mm, respectively. The maximum failure load and stiffness in group A were significantly higher than those in groups B and C, but which were significantly lower than those in group D (P<0.05).ConclusionNi-Ti three-dimensional memory alloy mesh combined with autologous bone can repair the Schatzker type Ⅲ tibial plateau collapse fracture, which has better biomechanical properties than simple autologous bone grafting.

Citation： YAN Zhaokui, LIANG Yu, FANG Yue, YAO Xiangyu, MA Kunlong, HUANG Fuguo. Biomechanical study of nickel-titanium three-dimensional memory alloy mesh and autologous bone in treatment of canine tibial plateau collapse fracture. Chinese Journal of Reparative and Reconstructive Surgery, 2018, 32(6): 722-725. doi: 10.7507/1002-1892.201709068 Copy

1.	Marsh JL, Slongo TF, Agel J, et al. Fracture and dislocation classification compendium-2007: Orthopaedic Trauma Association classification, database and outcomes committee. J Orthop Trauma, 2007, 21(10 Suppl): S1-133.
2.	賈濤, 張雅麗, 賈明聰. 脛骨平臺骨折 225 例的流行病學特征及臨床分析. 骨與關節損傷雜志, 2004, 19(9): 623-624.
3.	蔡春水, 張毅, 趙新建, 等. 脛骨平臺塌陷和劈裂骨折的手術治療. 中國矯形外科雜志, 2003, 11(23): 1611-1612.
4.	劉文亮, 肖鵬, 梁恒星, 等. 新型復合型人工氣管移植實驗研究. 中國修復重建外科雜志, 2013, 23(3): 330-334.
5.	Wressnegger A, Kaider A, Funovics MA. Self-expanding nitinol stents of high versus low chronic outward force in de novo femoropopliteal occlusive arterial lesions (BIOFLEX-COF trial): study protocol for a randomized controlled trial. Trails, 2017, 18(1): 594.
6.	Rawlinson JN. Morbidity after anterior cervical decompression and fusion. The influence of the donor site on recovery, and the results of a trial of surgibone compared to autologous bone. Acta Neurochir (Wien), 1994, 131(1-2): 106-118.
7.	Blokhuis TJ, Calori GM, Schmidmaier G. Autograft versus BMPs for the treatment of non-unions: what is the evidence. Injury, 2013, 44(Suppl 1): S40-S42.
8.	Boden SD. Overview of the biology of lumbar spine fusion and principles for selecting a bone graft substitute. Spine (Phila Pa 1976), 2002, 27(16 Suppl 1): S26-S31.
9.	Cornell CN. Osteoconductive materials and their role as substitutes for autogenous bone grafts. Orthop Clin North Am, 1999, 30(4): 591-598.
10.	Lattanzi W, Pola E, Pecorini G, et al. Gene therapy for in vivo bone formation:recent advances. Eur Rev Med Pharmacol Sci, 2005, 9(3): 167-174.
11.	羅越魁, 郭鵬鳴, 李斌, 等. 鎳鈦合金支架聯合自體心包重建長段氣管的動物實驗. 中國修復重建外科雜志, 2015, 11(29): 1419-1422.
12.	Serrano C, Lostalé F, Rodríguez-Panadero F, et al. Tracheal self-expandable metallic stents: a comparative study of three different stents in a rabbit model. Arch Bronconeumol, 2016, 52(3): 123-130.
13.	Haykal S, Salna M, Waddell TK, et al. Advances in tracheal reconstruction. Plast Reconstr Surg Glob Open, 2014, 2(7): e178.
14.	劉欣偉, 王攀峰, 付青格, 等. 動力髖螺釘結合記憶合金弓齒釘治療股骨粗隆下 Seinsheimer Ⅴ型粉碎性骨折. 中國骨傷, 2010, 23(4): 288-290.
15.	Liu X, Xu S, Zhang C, et al. Application of a shape-memory alloy internal fixator for treatment of acetabular fractures with a follow-up of two to nine years in China. Int Orthop, 2010, 34(7): 1033-1040.
16.	Su J, Liu X, Yu B, et al. Shape memory Ni-Ti alloy swan-like bone connector for treatment of humeral shaft nonunion. Int Orthop, 2010, 34(3): 369-375.
17.	林斌, 王巖, 趙衛東, 等. 鎳鈦記憶合金網球治療股骨頭缺血性壞死的生物力學及三維有限元分析. 中國矯形外科雜志, 2003, 11(15): 1059-1062.
18.	趙定麟, 張文明. 形狀記憶合金椎間關節用于頸椎病前路減壓術. 中華外科雜志, 1984, 22(7): 410-412.
19.	呂曉華, 陳根元, 曲國欣, 等. 鎳鈦形態記憶合金環抱器與重建鋼板置入內固定治療尺橈骨中段骨折的比較. 中國組織工程研究與臨床康復, 2010, 52(14): 9827-9830.
20.	王巖, 趙德偉, 王繼芳, 等. 鎳-鈦記憶合金網球治療成人股骨頭缺血性壞死初步報告. 中華外科雜志, 1998, 36(10): 579-581.

1. Marsh JL, Slongo TF, Agel J, et al. Fracture and dislocation classification compendium-2007: Orthopaedic Trauma Association classification, database and outcomes committee. J Orthop Trauma, 2007, 21(10 Suppl): S1-133.
2. 賈濤, 張雅麗, 賈明聰. 脛骨平臺骨折 225 例的流行病學特征及臨床分析. 骨與關節損傷雜志, 2004, 19(9): 623-624.
3. 蔡春水, 張毅, 趙新建, 等. 脛骨平臺塌陷和劈裂骨折的手術治療. 中國矯形外科雜志, 2003, 11(23): 1611-1612.
4. 劉文亮, 肖鵬, 梁恒星, 等. 新型復合型人工氣管移植實驗研究. 中國修復重建外科雜志, 2013, 23(3): 330-334.
5. Wressnegger A, Kaider A, Funovics MA. Self-expanding nitinol stents of high versus low chronic outward force in de novo femoropopliteal occlusive arterial lesions (BIOFLEX-COF trial): study protocol for a randomized controlled trial. Trails, 2017, 18(1): 594.
6. Rawlinson JN. Morbidity after anterior cervical decompression and fusion. The influence of the donor site on recovery, and the results of a trial of surgibone compared to autologous bone. Acta Neurochir (Wien), 1994, 131(1-2): 106-118.
7. Blokhuis TJ, Calori GM, Schmidmaier G. Autograft versus BMPs for the treatment of non-unions: what is the evidence. Injury, 2013, 44(Suppl 1): S40-S42.
8. Boden SD. Overview of the biology of lumbar spine fusion and principles for selecting a bone graft substitute. Spine (Phila Pa 1976), 2002, 27(16 Suppl 1): S26-S31.
9. Cornell CN. Osteoconductive materials and their role as substitutes for autogenous bone grafts. Orthop Clin North Am, 1999, 30(4): 591-598.
10. Lattanzi W, Pola E, Pecorini G, et al. Gene therapy for in vivo bone formation:recent advances. Eur Rev Med Pharmacol Sci, 2005, 9(3): 167-174.
11. 羅越魁, 郭鵬鳴, 李斌, 等. 鎳鈦合金支架聯合自體心包重建長段氣管的動物實驗. 中國修復重建外科雜志, 2015, 11(29): 1419-1422.
12. Serrano C, Lostalé F, Rodríguez-Panadero F, et al. Tracheal self-expandable metallic stents: a comparative study of three different stents in a rabbit model. Arch Bronconeumol, 2016, 52(3): 123-130.
13. Haykal S, Salna M, Waddell TK, et al. Advances in tracheal reconstruction. Plast Reconstr Surg Glob Open, 2014, 2(7): e178.
14. 劉欣偉, 王攀峰, 付青格, 等. 動力髖螺釘結合記憶合金弓齒釘治療股骨粗隆下 Seinsheimer Ⅴ型粉碎性骨折. 中國骨傷, 2010, 23(4): 288-290.
15. Liu X, Xu S, Zhang C, et al. Application of a shape-memory alloy internal fixator for treatment of acetabular fractures with a follow-up of two to nine years in China. Int Orthop, 2010, 34(7): 1033-1040.
16. Su J, Liu X, Yu B, et al. Shape memory Ni-Ti alloy swan-like bone connector for treatment of humeral shaft nonunion. Int Orthop, 2010, 34(3): 369-375.
17. 林斌, 王巖, 趙衛東, 等. 鎳鈦記憶合金網球治療股骨頭缺血性壞死的生物力學及三維有限元分析. 中國矯形外科雜志, 2003, 11(15): 1059-1062.
18. 趙定麟, 張文明. 形狀記憶合金椎間關節用于頸椎病前路減壓術. 中華外科雜志, 1984, 22(7): 410-412.
19. 呂曉華, 陳根元, 曲國欣, 等. 鎳鈦形態記憶合金環抱器與重建鋼板置入內固定治療尺橈骨中段骨折的比較. 中國組織工程研究與臨床康復, 2010, 52(14): 9827-9830.
20. 王巖, 趙德偉, 王繼芳, 等. 鎳-鈦記憶合金網球治療成人股骨頭缺血性壞死初步報告. 中華外科雜志, 1998, 36(10): 579-581.

Chinese Journal of Reparative and Reconstructive Surgery

Biomechanical study of nickel-titanium three-dimensional memory alloy mesh and autologous bone in treatment of canine tibial plateau collapse fracture

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content