Research progress on threshold values of 24-hour multichannel intraluminal impedance-pH monitoring in different regional populations_West China Medical Journal

Authors：

HUANG Ping ¹ , GUO Hao ¹ , XIONG Xin ² , XU Zhihong ² , ZHANG Xiumei ² , TANG Shilin ² , CHEN Yuan ² ,  HE Suyu ^1,2

1. School of Clinical Medicine, North Sichuan Medical College, Nanchong, Sichuan 637000, P. R. China;
2. Department of Gastroenterology, Suining Central Hospital, Suining, Sichuan 629000, P. R. China;

Corresponding?author：

HE Suyu, Email: hesuyu2009@163.com

Keywords：

Twenty-four-hour multichannel intraluminal impedance-pH monitoring; gastroesophageal reflux disease; threshold; regional differences

DOI：

10.7507/1002-0179.202509017

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Abstract Full text Figures/Tables Video References Cited by

Twenty-four-hour multichannel intraluminal impedance-pH (24 h MII-pH) monitoring is the gold standard for diagnosing gastroesophageal reflux disease. Owing to differences in genetic background, dietary habits, and lifestyle across populations in different countries and regions, the diagnostic thresholds of 24 h MII-pH may also vary among different populations. This article reviews relevant domestic and international literature to summarize current research progress on 24 h MII-pH diagnostic thresholds among different population groups in Asia, North America, Europe, and other regions. Furthermore, this paper conducts an in-depth analysis of regional variations in thresholds and their underlying influencing factors from perspectives including race and genetic background, dietary habits, and lifestyle factors.

Citation： HUANG Ping, GUO Hao, XIONG Xin, XU Zhihong, ZHANG Xiumei, TANG Shilin, CHEN Yuan, HE Suyu. Research progress on threshold values of 24-hour multichannel intraluminal impedance-pH monitoring in different regional populations. West China Medical Journal, 2026, 41(8): 1384-1390. doi: 10.7507/1002-0179.202509017 Copy

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West China Medical Journal

Research progress on threshold values of 24-hour multichannel intraluminal impedance-pH monitoring in different regional populations

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