Research on the awareness and clinical needs of wearable artificial kidney among maintenance hemodialysis patients_West China Medical Journal

Authors：

CHEN Shanshan ¹ , LI Yupei ¹ , YANG Mei ² ,  SU Baihai ^1,3 , ZHAO Changsheng ^3,4,5

1. Department of Nephrology and Kidney Research Institute, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;
2. Department of Nephrology, the First People’s Hospital of Shuangliu District, Chengdu, Sichuan 610200, P. R. China;
3. Med-X Center for Materials, Sichuan University, Chengdu, Sichuan 610041, P. R. China;
4. College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials and Engineering, Sichuan University, Chengdu, Sichuan 610065, P. R. China;
5. College of Chemical Engineering, Sichuan University, Chengdu, Sichuan 610065, P. R. China;

Corresponding?author：

SU Baihai, Email: subaihai@scu.edu.cn

Keywords：

Maintenance hemodialysis; wearable artificial kidney; investigation

DOI：

10.7507/1002-0179.202205139

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Objective To investigate the awareness and clinical needs of wearable artificial kidney among maintenance hemodialysis (MHD) patients, and to analyze the related influencing factors. Methods MHD patients were recruited from 2 tertiary hospitals in Sichuan province between April and June 2021. The convenient sampling method was used to select patients. The factors influencing the awareness and demand of MHD patients for wearable artificial kidney were analyzed. Results A total of 119 MHD patients were included. The awareness of wearable artificial kidney among the patients was mainly “never heard” (61 cases) and “heard” (58 cases). Most MHD patients (60 cases) were willing to use and participate in clinical trials in the future. The results of logistic regression indicated that the cost on household economy and treatment effect on life quality were the influencing factors for MHD patients’ awareness of wearable artificial kidney (P＜0.05). The average duration of single dialysis and the impact of treatment on working or studying were the influencing factors for MHD patients’ needs of wearable artificial kidney (P＜0.05). Conclusions The awareness of wearable artificial kidney is low among MHD patients. However, most MHD patients showed great interest in the wearable artificial kidney after preliminary understanding, suggesting that the future clinical application of wearable artificial kidney has great demand.

Citation： CHEN Shanshan, LI Yupei, YANG Mei, SU Baihai, ZHAO Changsheng. Research on the awareness and clinical needs of wearable artificial kidney among maintenance hemodialysis patients. West China Medical Journal, 2023, 38(7): 1034-1041. doi: 10.7507/1002-0179.202205139 Copy

1.	Zhang L, Zhao MH, Zuo L, et al. China Kidney Disease Network (CK-NET) 2015 Annual Data Report. Kidney Int Suppl (2011), 2019, 9(1): e1-e81.
2.	National Kidney Foundation. K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Am J Kidney Dis, 2002, 39 (2 Suppl 1): S1-S266.
3.	李菊, 李建蘭, 高愛民. 中國終末期腎病患者行維持性血液透析的流行病學現況. 實用臨床醫藥雜志, 2018, 22(21): 160-162.
4.	中國醫師協會腎臟病醫師分會血液透析充分性協作組. 中國血液透析充分性臨床實踐指南. 中華醫學雜志, 2015, 95(34): 2748-2753.
5.	張曉慶, 張紅梅, 常立陽. 維持性血液透析患者癥狀負擔的調查與分析. 中國中西醫結合腎病雜志, 2016, 17(9): 818-820.
6.	肖小玉. 血液透析患者日常生活能力現狀的調查分析. 臨床醫學工程, 2013, 20(11): 1451-1452.
7.	翁曉羽, 徐淑娟, 陶明芬, 等. 維持性血液透析患者家庭日常活動狀況相關因素分析. 長江大學學報(自然科學版), 2019, 16(6): 98-102.
8.	農生斌, 楊發奮. 維持性血液透析患者生存質量及影響因素的研究進展. 右江醫學, 2020, 48(1): 70-75.
9.	陳虹宇. 終末期腎病患者疾病直接經濟負擔調查研究. 廣州: 廣州中醫藥大學, 2010.
10.	田詩音. 我國慢性腎臟病疾病負擔與患者生命質量研究. 上海: 中國人民解放軍海軍軍醫大學, 2022.
11.	趙偉鋒, 孫樹東, 趙長生. 聚醚砜血液凈化膜的研究進展. 高分子通報, 2017(10): 80-88.
12.	趙長生, 趙偉鋒, 張翔, 等. 新型血液凈化材料及佩戴式人工腎的研究構想和預期成果展望. 工程科學與技術, 2018, 50(1): 1-8.
13.	劉秀娟, 涂曉文, 黃國明. 可佩戴型人工腎的研究進展. 中國臨床醫學, 2012, 19(1): 89-90.
14.	Gura V, Rivara MB, Bieber S, et al. A wearable artificial kidney for patients with end-stage renal disease. JCI Insight, 2016, 1(8): e86397.
15.	Salani M, Roy S, Fissell WH 4th. Innovations in wearable and implantable artificial kidneys. Am J Kidney Dis, 2018, 72(5): 745-751.
16.	Castro AC, Neri M, Nayak Karopadi A, et al. Wearable artificial kidney and wearable ultrafiltration device vascular access-future directions. Clin Kidney J, 2018, 12(2): 300-307.
17.	Ramada DL, de Vries J, Vollenbroek J, et al. Portable, wearable and implantable artificial kidney systems: needs, opportunities and challenges. Nat Rev Nephrol, 2023: 1-10.
18.	孫振球. 醫學統計學. 3 版. 北京: 人民衛生出版社, 2007: 293.
19.	張曉華, 李靜, 王利華. 近 5 年維持性血液透析患者的流行病學調查分析. 中國血液凈化, 2015, 14(11): 698-702.
20.	吳佳. 維持性血液透析患者家庭動力學改變相關研究. 成都: 成都醫學院, 2022.
21.	周煜, 王文秀, 曹曉翼, 等. 維持性血液透析患者自我管理行為及影響因素研究. 華西醫學, 2021, 36(8): 1077-1082.
22.	郎曉慧, 白玉賢, 李惠艷, 等. 腫瘤患者對新藥臨床試驗參與意愿影響因素的調查. 哈爾濱醫科大學學報, 2019, 53(5): 544-548.
23.	Chu SH, Kim EJ, Jeong SH, et al. Factors associated with willingness to participate in clinical trials: a nationwide survey study. BMC Public Health, 2015, 15: 10.
24.	Comis RL, Miller JD, Aldigé CR, et al. Public attitudes toward participation in cancer clinical trials. J Clin Oncol, 2003, 21(5): 830-835.
25.	徐宜詠, 曹羽明, 李斐, 等. 武漢某醫院門診患者對藥物臨床試驗知曉度分析. 武漢大學學報(醫學版), 2016, 37(6): 1023-1026, 1034.

1. Zhang L, Zhao MH, Zuo L, et al. China Kidney Disease Network (CK-NET) 2015 Annual Data Report. Kidney Int Suppl (2011), 2019, 9(1): e1-e81.
2. National Kidney Foundation. K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Am J Kidney Dis, 2002, 39 (2 Suppl 1): S1-S266.
3. 李菊, 李建蘭, 高愛民. 中國終末期腎病患者行維持性血液透析的流行病學現況. 實用臨床醫藥雜志, 2018, 22(21): 160-162.
4. 中國醫師協會腎臟病醫師分會血液透析充分性協作組. 中國血液透析充分性臨床實踐指南. 中華醫學雜志, 2015, 95(34): 2748-2753.
5. 張曉慶, 張紅梅, 常立陽. 維持性血液透析患者癥狀負擔的調查與分析. 中國中西醫結合腎病雜志, 2016, 17(9): 818-820.
6. 肖小玉. 血液透析患者日常生活能力現狀的調查分析. 臨床醫學工程, 2013, 20(11): 1451-1452.
7. 翁曉羽, 徐淑娟, 陶明芬, 等. 維持性血液透析患者家庭日常活動狀況相關因素分析. 長江大學學報(自然科學版), 2019, 16(6): 98-102.
8. 農生斌, 楊發奮. 維持性血液透析患者生存質量及影響因素的研究進展. 右江醫學, 2020, 48(1): 70-75.
9. 陳虹宇. 終末期腎病患者疾病直接經濟負擔調查研究. 廣州: 廣州中醫藥大學, 2010.
10. 田詩音. 我國慢性腎臟病疾病負擔與患者生命質量研究. 上海: 中國人民解放軍海軍軍醫大學, 2022.
11. 趙偉鋒, 孫樹東, 趙長生. 聚醚砜血液凈化膜的研究進展. 高分子通報, 2017(10): 80-88.
12. 趙長生, 趙偉鋒, 張翔, 等. 新型血液凈化材料及佩戴式人工腎的研究構想和預期成果展望. 工程科學與技術, 2018, 50(1): 1-8.
13. 劉秀娟, 涂曉文, 黃國明. 可佩戴型人工腎的研究進展. 中國臨床醫學, 2012, 19(1): 89-90.
14. Gura V, Rivara MB, Bieber S, et al. A wearable artificial kidney for patients with end-stage renal disease. JCI Insight, 2016, 1(8): e86397.
15. Salani M, Roy S, Fissell WH 4th. Innovations in wearable and implantable artificial kidneys. Am J Kidney Dis, 2018, 72(5): 745-751.
16. Castro AC, Neri M, Nayak Karopadi A, et al. Wearable artificial kidney and wearable ultrafiltration device vascular access-future directions. Clin Kidney J, 2018, 12(2): 300-307.
17. Ramada DL, de Vries J, Vollenbroek J, et al. Portable, wearable and implantable artificial kidney systems: needs, opportunities and challenges. Nat Rev Nephrol, 2023: 1-10.
18. 孫振球. 醫學統計學. 3 版. 北京: 人民衛生出版社, 2007: 293.
19. 張曉華, 李靜, 王利華. 近 5 年維持性血液透析患者的流行病學調查分析. 中國血液凈化, 2015, 14(11): 698-702.
20. 吳佳. 維持性血液透析患者家庭動力學改變相關研究. 成都: 成都醫學院, 2022.
21. 周煜, 王文秀, 曹曉翼, 等. 維持性血液透析患者自我管理行為及影響因素研究. 華西醫學, 2021, 36(8): 1077-1082.
22. 郎曉慧, 白玉賢, 李惠艷, 等. 腫瘤患者對新藥臨床試驗參與意愿影響因素的調查. 哈爾濱醫科大學學報, 2019, 53(5): 544-548.
23. Chu SH, Kim EJ, Jeong SH, et al. Factors associated with willingness to participate in clinical trials: a nationwide survey study. BMC Public Health, 2015, 15: 10.
24. Comis RL, Miller JD, Aldigé CR, et al. Public attitudes toward participation in cancer clinical trials. J Clin Oncol, 2003, 21(5): 830-835.
25. 徐宜詠, 曹羽明, 李斐, 等. 武漢某醫院門診患者對藥物臨床試驗知曉度分析. 武漢大學學報(醫學版), 2016, 37(6): 1023-1026, 1034.

West China Medical Journal

Research on the awareness and clinical needs of wearable artificial kidney among maintenance hemodialysis patients

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content