Level of blood pressure and hypertension prevalence and influencing factors in middle-aged population with positive family history of hypertension_West China Medical Journal

Authors：

WU Yu ^1,2 , ZHANG Yang ¹ , TANG Weiwei ³ ,  HUANG Xiaobo ¹ , LIU Jianxiong ¹ , LIU Ya ⁴ , HU Yongmei ¹ , NIE Xiaoli ¹ , LI Qiu ¹ , OUYANG Lingyun ⁴

1. Department of Cardiology, Chengdu Second People’s Hospital, Chengdu, Sichuan 610017, P. R. China;
2. Department of Cardiology, People’s Hospital of the Central District of Leshan, Leshan, Sichuan 614000, P. R. China;
3. School of Health Policy & Management, Nanjing Medical University, Nanjing, Jiangsu 211166, P. R. China;
4. Department of Endocrinology, Chengdu Second People’s Hospital, Chengdu, Sichuan 610017, P. R. China;

Corresponding?author：

HUANG Xiaobo, Email: drhuangxiaobo@126.com

Keywords：

Positive family history of hypertension; Hypertension; Prevalence; Risk factors

DOI：

10.7507/1002-0179.201902013

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Objective To investigate the blood pressure level and prevalence of hypertension in middle-aged people with positive family history of hypertension in Chengdu area, compare the differences between middle-aged people with positive family history of hypertension and middle-aged people with negative family history of hypertension, and explore the influencing factors of hypertension in middle-aged people with positive family history of hypertension.Methods From September 2013 to March 2014, the stratified sampling method was used to survey 3 096 middle-aged people aged 40-59 years in Chengdu. Their height, weight, blood pressure, blood glucose, and blood lipids were measured. Questionnaire surveys were conducted using a uniformly designed questionnaire. The blood pressure levels and hypertension prevalences were compared between people with and without positive family history of hypertension. The influencing factors of hypertension in middle-aged people with positive family history of hypertension were analyzed using multiple logistic regression.Results There were significant differences between the middle-aged people with positive family history of hypertension and the ones with negative family history of hypertension in systolic blood pressure [(137.4±22.4) vs. (118.0±11.3) mm Hg (1 mm Hg=0.133 kPa), P<0.001], diastolic blood pressure [(84.1±12.2) vs. (73.9±7.7) mm Hg, P<0.001], and prevalence of hypertension (28.6% vs. 22.2%, P<0.001). Ageing [odds ratio (OR)=1.107, 95% confidence interval (CI) (1.071, 1.144), P<0.001], monthly personal income ≥3 000 yuan [OR=1.566, 95%CI (1.003, 2.445), P=0.048], and abdominal obesity [OR=1.658, 95%CI (1.091, 2.520), P=0.018] were the risk factors for hypertension in middle-aged males with positive family history. Ageing [OR=2.257, 95%CI (1.202, 4.025), P=0.026] and overweight or obesity [OR=2.365, 95%CI (1.653, 3.385), P<0.001] were the risk factors, and physical exercise [OR=0.529, 95%CI (0.304, 0.918), P=0.024] was the protective factor for hypertension in middle-aged females with positive family history.Conclusions The prevalence of hypertension is high in middle-aged population with positive family history of hypertension in Chengdu and is significantly higher than that in the ones with negative family history of hypertension. Strengthening health education on hypertension-related knowledge, and reasonably controlling waist circumference and body weight may have positive significance in preventing or delaying the occurrence of hypertension in people with positive family history of hypertension.

Citation： WU Yu, ZHANG Yang, TANG Weiwei, HUANG Xiaobo, LIU Jianxiong, LIU Ya, HU Yongmei, NIE Xiaoli, LI Qiu, OUYANG Lingyun. Level of blood pressure and hypertension prevalence and influencing factors in middle-aged population with positive family history of hypertension. West China Medical Journal, 2019, 34(9): 1022-1027. doi: 10.7507/1002-0179.201902013 Copy

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10.	黃廣勇, 顧東風, 吳錫桂, 等. 父母高血壓史對子女高血壓患病率及血壓水平的影響. 高血壓雜志, 2002, 10(3): 274-277.
11.	吳小艷, 李強, 嚴惠, 等. 陜西省漢中市農村居民高血壓與家族史的相關性分析. 中華流行病學雜志, 2017, 38(8): 1050-1054.
12.	黃曉波, 胡蓉, 樂慶榮, 等. 重慶市城鄉居民高血壓患病及影響因素分析. 中國公共衛生, 2009, 25(1): 25-27.
13.	Li T, Xian Y, Mao HM, et al. Prevalence, awareness, treatment and control of high blood pressure among Chinese rural population in Haimen, Jiangsu. J Hum Hypertens, 2016, 30(4): 225-230.
14.	Huang XB, Chen F, Dai W, et al. Prevalence and risk factors associated with hypertension in the Chinese Qiang population. Clin Exp Hypertens, 2018, 40(5): 427-433.
15.	馮超, 張衛東, 孫榮國, 等. 1355例公務員超重肥胖及其與高血壓的相關性分析. 華西醫學, 2008, 23(3): 542-543.

1. Kearney PM, Whelton M, Reynolds K, et al. Global burden of hypertension: analysis of worldwide data. Lancet, 2005, 365(9455): 217-223.
2. Wang Z, Chen Z, Zhang L, et al. Status of hypertension in China: results from the China Hypertension Survey, 2012-2015. Circulation, 2018, 137(22): 2344-2356.
3. 中國高血壓防治指南修訂委員會. 中國高血壓防治指南2010. 中華高血壓雜志, 2011, 19(8): 701-743.
4. 中國肥胖問題工作組數據匯總分析協作組. 我國成人體重指數和腰圍對相關疾病危險因素異常的預測價值: 適宜體重指數和腰圍切點的研究. 中華流行病學雜志, 2002, 23(1): 5-10.
5. 中國成人血脂異常防治指南修訂聯合委員會. 中國成人血脂異常防治指南(2016年修訂版). 中國循環雜志, 2016, 31(10): 937-950.
6. Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care, 2003, 26(Suppl 1): S5-S20.
7. 劉東霞, 華琦, 郭金成, 等. 有家族史與無家族史高血壓病患者發病特點及危險因素的調查分析. 心肺血管病雜志, 2006, 25(2): 71-74.
8. 中國醫師協會腎臟內科醫師分會. 中國腎臟疾病高尿酸血癥診治的實踐指南(2017版). 中華醫學雜志, 2017, 97(25): 1927-1936.
9. Huang XB, Tang WW, Liu Y, et al. Prevalence of diabetes and unrecognized diabetes in hypertensive patients aged 40 to 79 years in southwest China. PLoS One, 2017, 12(2): e0170250.
10. 黃廣勇, 顧東風, 吳錫桂, 等. 父母高血壓史對子女高血壓患病率及血壓水平的影響. 高血壓雜志, 2002, 10(3): 274-277.
11. 吳小艷, 李強, 嚴惠, 等. 陜西省漢中市農村居民高血壓與家族史的相關性分析. 中華流行病學雜志, 2017, 38(8): 1050-1054.
12. 黃曉波, 胡蓉, 樂慶榮, 等. 重慶市城鄉居民高血壓患病及影響因素分析. 中國公共衛生, 2009, 25(1): 25-27.
13. Li T, Xian Y, Mao HM, et al. Prevalence, awareness, treatment and control of high blood pressure among Chinese rural population in Haimen, Jiangsu. J Hum Hypertens, 2016, 30(4): 225-230.
14. Huang XB, Chen F, Dai W, et al. Prevalence and risk factors associated with hypertension in the Chinese Qiang population. Clin Exp Hypertens, 2018, 40(5): 427-433.
15. 馮超, 張衛東, 孫榮國, 等. 1355例公務員超重肥胖及其與高血壓的相關性分析. 華西醫學, 2008, 23(3): 542-543.

West China Medical Journal

Level of blood pressure and hypertension prevalence and influencing factors in middle-aged population with positive family history of hypertension

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