Dominant distribution and pathological basis of thin layer 16-slice spiral CT signs of coal workers’ pneumoconiosis_West China Medical Journal

Authors：

WEN Xiaoling , WU Dongsheng , CAI Shu , YANG Yuxiang , LI Ye ,  SHEN Jiang

Department of Radiology, NO. 4 West China Teaching Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;

Corresponding?author：

SHEN Jiang, Email: 474812264@qq.com

Keywords：

Coal worker’s pneumoconiosis; Tomography, X-ray computed; Anatomy; Pathology

DOI：

10.7507/1002-0179.201809058

Video：

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Abstract Full text Figures/Tables Video References Cited by

Objective To clarify the thin-layer 16-slice spiral CT features of coal worker’s pneumoconiosis and the superior distribution of comorbidities in their staging and lobes and lung field anatomy. Methods Sixty-six patients with coal worker's pneumoconiosis diagnosed by the pneumoconiosis diagnosis and identification group from October 2014 to March 2015 were enrolled. All patients underwent 16-slice spiral CT and thin-layer CT reconstruction with a thickness of 1.5 mm. The thin-slice CT signs and comorbidities of coal workers’ pneumoconiosis were observed, and the superior distribution of CT signs in patients at different stage and different lobes and lung field anatomy were evaluated. Results There were 16 cases of irregular small nodules in the lungs, 22 cases of large shadow fusion, 18 cases of intraocular shadow calcification, 41 cases of emphysema, 21 cases of pulmonary bullae, 21 cases of pulmonary hypertension, and 31 cases of enlarged lymph nodes in the mediastinum and calcified. The above signs were mostly distributed in stage Ⅲ pneumoconiosis (P<0.05). There were 32 cases of regular small nodules, which were mostly distributed in stage Ⅰ pneumoconiosis. In the 16 cases of irregular small nodules, the advantage was distributed in the middle and outer lobes of the double lungs. In the 22 cases of large shadow fusion, the advantage was distributed in the upper and lower lobe of the lungs. In the 16 cases of tuberculosis, the advantage was distributed in the upper lobe of the lungs. In the 21 cases of bullous bullae, the advantage was distributed in the upper lobe of the two lungs, mostly in the right upper lung. Conclusion The thin 16-slice spiral CT signs of coal worker’s pneumoconiosis can reflect the pathological changes, and have a certain correlation with the stage of pneumoconiosis, and have obvious characteristics in the anatomical distribution of lung and lung fields.

Citation： WEN Xiaoling, WU Dongsheng, CAI Shu, YANG Yuxiang, LI Ye, SHEN Jiang. Dominant distribution and pathological basis of thin layer 16-slice spiral CT signs of coal workers’ pneumoconiosis. West China Medical Journal, 2019, 34(1): 30-34. doi: 10.7507/1002-0179.201809058 Copy

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5.	Xia Y, Liu J, Shi T, et al. Prevalence of pneumoconiosis in Hubei, China from 2008 to 2013. Int J Environ Res Public Health, 2014, 11(9): 8612-8621.
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7.	Tomaskova H, Jirak Z, Splichalova A, et al. Cancer incidence in czech black coal miners in association with coalworkers’ pneumoconiosis. Int J Occup Med Environ Health, 2012, 25(2): 137-144.
8.	Alt?nsoy B, ?z ??, Erboy F, et al. Emphysema and airflow obstruction in non-smoking coal miners with pneumoconiosis. Med Sci Monit, 2016, 22: 4887-4893.
9.	Ma J, Cui X, Rong Y, et al. Plasma LncRNA-ATB, a potential biomarker for diagnosis of patients with coal workers’ pneumoconiosis: a case-control study. Int J Mol Sci, 2016, 17(8): E1367.
10.	高勁松, 李鳳, 陳壘. 煤工塵肺合并肺結核 1 130 例分析. 中國工業醫學雜志, 2014, 27(5): 381-382.
11.	Mutlu GM, Green D, Bellmeyer A, et al. Ambient particulate matter accelerates coagulation via an IL-6-dependent pathway. J Clin Invest, 2007, 117(10): 2952-2961.
12.	Brook RD, Rajagopalan S, Pope CA 3rd, et al. Particulate matter air pollution and cardiovascular disease: an update to the scientific statement from the American Heart Association. Circulation, 2010, 121(21): 2331-2378.
13.	Akkoca Yildiz O, Eris Gulbay B, Saryal S, et al. Evaluation of the relationship between radiological abnormalities and both pulmonary function and pulmonary hypertension in coal workers’ pneumoconiosis. Respirology, 2007, 12(3): 420-426.
14.	江瑞康, 王玉玲, 劉培成. 尸檢煤工塵肺進行性大塊纖維化的病理學觀察. 中華勞動衛生職業病雜志, 2014, 32(9): 701-703.
15.	Kam JC, Pi J, Doraiswamy V, et al. CT scanning in the evaluation of pulmonary hypertension. Lung, 2013, 191(4): 321-326.

1. Wang T, Ji X, Luo C, et al. Polymorphisms in SELE gene and risk of coal workers’ pneumoconiosis in Chinese: a case-control study. PLoS One, 2013, 8(9): e73254.
2. 中華人民共和國衛生部. 塵肺病診斷標準: GBZ 70－2009, 2009.
3. Cohen RA, Petsonk EL, Rose C, et al. Lung pathology in U.S. coal workers with rapidly progressive pneumoconiosis implicates silica and silicates. Am J Respir Crit Care Med, 2016, 193(6): 673-680.
4. Mo J, Wang L, Au W, et al. Prevalence of coal workers’ pneumoconiosis in China: a systematic analysis of 2001-2011 studies. Int J Hyg Environ Health, 2014, 217(1): 46-51.
5. Xia Y, Liu J, Shi T, et al. Prevalence of pneumoconiosis in Hubei, China from 2008 to 2013. Int J Environ Res Public Health, 2014, 11(9): 8612-8621.
6. Jun JS, Jung JI, Kim HR, et al. Complications of pneumoconiosis: radiology overview. Eur J Radiol, 2013, 82(10): 1819-1830.
7. Tomaskova H, Jirak Z, Splichalova A, et al. Cancer incidence in czech black coal miners in association with coalworkers’ pneumoconiosis. Int J Occup Med Environ Health, 2012, 25(2): 137-144.
8. Alt?nsoy B, ?z ??, Erboy F, et al. Emphysema and airflow obstruction in non-smoking coal miners with pneumoconiosis. Med Sci Monit, 2016, 22: 4887-4893.
9. Ma J, Cui X, Rong Y, et al. Plasma LncRNA-ATB, a potential biomarker for diagnosis of patients with coal workers’ pneumoconiosis: a case-control study. Int J Mol Sci, 2016, 17(8): E1367.
10. 高勁松, 李鳳, 陳壘. 煤工塵肺合并肺結核 1 130 例分析. 中國工業醫學雜志, 2014, 27(5): 381-382.
11. Mutlu GM, Green D, Bellmeyer A, et al. Ambient particulate matter accelerates coagulation via an IL-6-dependent pathway. J Clin Invest, 2007, 117(10): 2952-2961.
12. Brook RD, Rajagopalan S, Pope CA 3rd, et al. Particulate matter air pollution and cardiovascular disease: an update to the scientific statement from the American Heart Association. Circulation, 2010, 121(21): 2331-2378.
13. Akkoca Yildiz O, Eris Gulbay B, Saryal S, et al. Evaluation of the relationship between radiological abnormalities and both pulmonary function and pulmonary hypertension in coal workers’ pneumoconiosis. Respirology, 2007, 12(3): 420-426.
14. 江瑞康, 王玉玲, 劉培成. 尸檢煤工塵肺進行性大塊纖維化的病理學觀察. 中華勞動衛生職業病雜志, 2014, 32(9): 701-703.
15. Kam JC, Pi J, Doraiswamy V, et al. CT scanning in the evaluation of pulmonary hypertension. Lung, 2013, 191(4): 321-326.

West China Medical Journal

Dominant distribution and pathological basis of thin layer 16-slice spiral CT signs of coal workers’ pneumoconiosis

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