Application of low-dose contrast agent combined with physiological saline in SOMATOM Definition Flash CT angiography for head and neck_West China Medical Journal

Authors：

LI Lei , ZHAO Fei , XIA Chunchao , LIU Lu ,  LI Zhenlin

Department of Radiology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;

Corresponding?author：

LI Zhenlin, Email: lzlcd01@126.com

Keywords：

Contrast media; Head and neck; Angiography; X-ray computed, tomography

DOI：

10.7507/1002-0179.201608324

Video：

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ObjectiveTo explore the clinical value of low-dose contrast agnet in CT angiography (CTA) for head and neck by SOMATOM Definition Flash CT.MethodsSixty consecutive patients with head and neck vessel diseases examined by CTA in the head and neck were chosen from West China Hospital of Sichuan University from March to July 2015, and then were randomly divided into two groups (the experimental group: n=30, 30 mL contrast medium; the control group: n=30, 50 mL contrast medium). Imaging post processing techniques included curved plannar reconstruction, volume rendering, and maximal intensity projection. CT values of the different level of carotid arteries (aortic arch, carotid bifuracation, and M1 segment of middle cerebral artery) were measured. The artifact of the remaining contract in the jugular vein and overall quality of the image were observed by two senior doctors using double blind method.ResultsAll the patients in the two groups completed CTA for head and neck successfully. The image qualities of the two groups satisfid clinical diagnostic requirements, and there was no difference in the image qualities between the two groups (P>0.05). The evaluation of venous pollution in the experimental group was lighter than that in the control group (P<0.05). The CT values of aortic arch, carotid bifuracation, and M1 segment of middle cerebral artery in the experimental group [(341.3±89.5), (391.0±103.7), (305.0±62.0) HU] were slightly lower than those in the control group [(437.3±83.7), (532.5±113.3), (396.6±93.1) HU], which were statistically significant (P<0.05).ConclusionLow-dose contrast in CTA for head and neck by SOMATOM Definition Flash CT can satisfy the clinical diagnostic requirements, and reduce the dose of contrast agent and venous pollution, with a good clinical value.

Citation： LI Lei, ZHAO Fei, XIA Chunchao, LIU Lu, LI Zhenlin. Application of low-dose contrast agent combined with physiological saline in SOMATOM Definition Flash CT angiography for head and neck. West China Medical Journal, 2018, 33(8): 1015-1018. doi: 10.7507/1002-0179.201608324 Copy

1.	李飛飛, 金彪, 鄒明, 等. 低劑量CT掃描技術在頭頸部CTA中的應用價值研究. 中國臨床醫學影像雜志, 2013, 24(11): 761-764.
2.	姜保東, 馮曉源, 柳澄, 等. 顱頸聯合多層螺旋CT血管造影掃描技術探討. 中華放射學雜志, 2006, 40(9): 970-973.
3.	Ajami G, Derakhshan A, Amoozgar HA, et al. Risk of nephropathy after consumption of nonionic contrast media by children undergoing cardiac angiography: a prospective study. Pediatr Cardiol, 2010, 31(5): 668-673.
4.	Briguori C, Airoldi F, Morici N, et al. New pharmacological protocols to prevent or reduce contrast media nephropathy. Minerva Cardioangiol, 2005, 53(1): 49-58.
5.	李磊, 趙飛, 蒲鈺鎂, 等. 低濃度對比劑結合雙低劑量在CT肺動脈血管成像中的臨床應用. 四川大學學報: 醫學版, 2018, 49(2): 239-242.
6.	王婕妤, 喬偉, 黎秋菊, 等. 低管電壓結合低劑量對比劑在64層螺旋CT頭頸部血管成像中的應用. 中國醫學影像學雜志, 2015(7): 481-485.
7.	夏巍, 尹肖睿, 吳晶濤, 等. 低管電壓結合低劑量對比劑在多層螺旋CT頭顱動脈血管成像中應用的可行性研究. 中華放射學雜志, 2013, 47(11): 984-987.
8.	張保翠, 張玉東, 趙凱, 等. 靜脈注射碘對比劑對不同人群腎功能的影響. 中華放射學雜志, 2013, 47(4): 335-339.
9.	李明利, 金征宇, 張云慶, 等. 多層螺旋CT頭頸部低劑量對比劑血管成像的可行性研究. 臨床放射學雜志, 2005, 24(3): 214-217.
10.	楊春燕, 侯新川, 梅友泉. 低劑量對比劑在64排CT頭頸部血管聯合成像中的應用. 中國醫學影像學雜志, 2012(5): 352-354.
11.	曹東興, 唐皓, 鄧克學. 采用低劑量掃描條件和低劑量對比劑行128層螺旋CT頭頸部動脈成像的可行性研究. 中國臨床保健雜志, 2013, 16(6): 591-593, 679.
12.	陳黎麗, 潘為領, 王學廷, 等. 低劑量對比劑在256層CT頭頸部血管成像中的應用. 醫學影像學雜志, 2013, 23(5): 672-674.
13.	周存升, 馬睿, 柳澄, 等. CTA對顱內動脈的顯示及成像技術探討. 中華放射學雜志, 1998(2): 55-56.
14.	Schoellnast H, Tillich M, Deutschmann MJ, et al. Aortoiliac enhancement during computed tomography angiography with reduced contrast material dose and saline solution flush - Influence on magnitude and uniformity of the contrast column. Invest Radiol, 2004, 39(1): 20-26.
15.	祁俊華, 吳煥閣, 于淑靖. 多層螺旋CT腦動脈成像的標準體位. 中國實用醫藥, 2007, 2(14): 13-15.

1. 李飛飛, 金彪, 鄒明, 等. 低劑量CT掃描技術在頭頸部CTA中的應用價值研究. 中國臨床醫學影像雜志, 2013, 24(11): 761-764.
2. 姜保東, 馮曉源, 柳澄, 等. 顱頸聯合多層螺旋CT血管造影掃描技術探討. 中華放射學雜志, 2006, 40(9): 970-973.
3. Ajami G, Derakhshan A, Amoozgar HA, et al. Risk of nephropathy after consumption of nonionic contrast media by children undergoing cardiac angiography: a prospective study. Pediatr Cardiol, 2010, 31(5): 668-673.
4. Briguori C, Airoldi F, Morici N, et al. New pharmacological protocols to prevent or reduce contrast media nephropathy. Minerva Cardioangiol, 2005, 53(1): 49-58.
5. 李磊, 趙飛, 蒲鈺鎂, 等. 低濃度對比劑結合雙低劑量在CT肺動脈血管成像中的臨床應用. 四川大學學報: 醫學版, 2018, 49(2): 239-242.
6. 王婕妤, 喬偉, 黎秋菊, 等. 低管電壓結合低劑量對比劑在64層螺旋CT頭頸部血管成像中的應用. 中國醫學影像學雜志, 2015(7): 481-485.
7. 夏巍, 尹肖睿, 吳晶濤, 等. 低管電壓結合低劑量對比劑在多層螺旋CT頭顱動脈血管成像中應用的可行性研究. 中華放射學雜志, 2013, 47(11): 984-987.
8. 張保翠, 張玉東, 趙凱, 等. 靜脈注射碘對比劑對不同人群腎功能的影響. 中華放射學雜志, 2013, 47(4): 335-339.
9. 李明利, 金征宇, 張云慶, 等. 多層螺旋CT頭頸部低劑量對比劑血管成像的可行性研究. 臨床放射學雜志, 2005, 24(3): 214-217.
10. 楊春燕, 侯新川, 梅友泉. 低劑量對比劑在64排CT頭頸部血管聯合成像中的應用. 中國醫學影像學雜志, 2012(5): 352-354.
11. 曹東興, 唐皓, 鄧克學. 采用低劑量掃描條件和低劑量對比劑行128層螺旋CT頭頸部動脈成像的可行性研究. 中國臨床保健雜志, 2013, 16(6): 591-593, 679.
12. 陳黎麗, 潘為領, 王學廷, 等. 低劑量對比劑在256層CT頭頸部血管成像中的應用. 醫學影像學雜志, 2013, 23(5): 672-674.
13. 周存升, 馬睿, 柳澄, 等. CTA對顱內動脈的顯示及成像技術探討. 中華放射學雜志, 1998(2): 55-56.
14. Schoellnast H, Tillich M, Deutschmann MJ, et al. Aortoiliac enhancement during computed tomography angiography with reduced contrast material dose and saline solution flush - Influence on magnitude and uniformity of the contrast column. Invest Radiol, 2004, 39(1): 20-26.
15. 祁俊華, 吳煥閣, 于淑靖. 多層螺旋CT腦動脈成像的標準體位. 中國實用醫藥, 2007, 2(14): 13-15.

West China Medical Journal

Application of low-dose contrast agent combined with physiological saline in SOMATOM Definition Flash CT angiography for head and neck

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