Effect of different nutritional support on the prognosis of severe community-acquired pneumonia_West China Medical Journal

Authors：

 ZHANG Yi ¹ , CHEN Pei ²

1. Medical Examination Center, Affiliated Hospital of Chengdu University, Chengdu, Sichuan 610081, P. R. China;
2. Department of Respiratory Medicine, Affiliated Hospital of Chengdu University, Chengdu, Sichuan 610081, P. R. China;

Corresponding?author：

ZHANG Yi, Email: 89610802@qq.com

Keywords：

Nutritional support; Community-acquired pneumonia; Prognosis

DOI：

10.7507/1002-0179.201601024

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Objective To investigate the clinical efficacy of nutritional support with different proportion of fat on the prognosis of patients with severe community-acquired pneumonia (SCAP). Methods Ninety SCAP patients with nutritional risk treated between January 2014 and July 2015 were randomized into high, normal, and low-proportion fat groups with 30 patients in each. The patients in different groups underwent nutritional support with different fat proportion besides the same medication. Data of albumin, pre-albumin and transferrin were collected and analyzed before treatment and 10 days after treatment. The mortality rates were compared between groups. Results Albumin, pre-albumin and transferrin were similar in all groups before intervention (P>0.05); albumin, pre-albumin and transferrin increased significantly 10 days after treatment in each group (P<0.05). Patients in the normal-fat group acquired significantly more obvious improvements on each index (P<0.05). A shorter length of stay in hospital was observed in the normal-proportion fat group compared with the high and low-proportion fat groups, but there was no significant differences among groups (P>0.05). On the 10th day, the normal -proportion fat proportion group had a significantly higher cure rate and a significantly lower mortality rate than the other two groups (P<0.05). The improvement rate was similar in all groups (P>0.05). Conclusion Supportive treatment with normal fat proportion has a promising value in the improvement of albumin, pre-albumin and transferrin for SCAP patients with a shorter length of stay in hospital, which is worthy of clinical promotion.

Citation： ZHANG Yi, CHEN Pei. Effect of different nutritional support on the prognosis of severe community-acquired pneumonia. West China Medical Journal, 2017, 32(2): 186-189. doi: 10.7507/1002-0179.201601024 Copy

1.	Lim WS, Baudouin SV, George RC,et al. BTS guidelines for the management of community acquired pneumonia in adults: update 2009. Thorax, 2009, 64(Suppl 3): 1-55.
2.	王玉光, 孫兆家. 375例慢性腦出血后肺炎患者病原菌分布及其預后影響因素分析. 中國生化藥物雜志, 2014, 34(2): 157-159.
3.	Mandell LA, Wunderink RG, Anzueto A,et al. Infectious diseases society of America/American thoracic society consensus guidelines on the management of community-acquired pneumonia in adults. Clin Infect Dis, 2007, 44(Suppl 2): S27-S72.
4.	Mercadal-Orfila G, Lluch-Taltavull J, Campillo-Artero C. Association between nutritional risk based on the NRS-2002 test and hospital morbidity and mortality. Nutr Hosp, 2012, 27(4): 1248-1254.
5.	李挺. 提高老年肺炎診斷的臨床分析. 中華實用醫藥雜志, 2004, 4(10): 413.
6.	Calleja Fernández A, Vidal Casariego A, Ballesteros Pomar MD. Comparative study of total energy expenditure estimated by sense wear armband and harris-benedictequation in healthy ambulatory population; utility in clincal practice. Nutr Hosp, 2012, 27(4): 1244-1247.
7.	周曉云. 大環內酯類抗菌藥物在下呼吸道感染患者中的應用效果. 華西醫學, 2015, 30(7): 1205-1208.
8.	Chatha N, Fortin D, Bosma KJ. Management of necrotizing pneumonia and pulmonary gangrene: a case series and review of the literature. Can Respir J, 2014, 21(4): 239-245.
9.	Nicolini A, Cilloniz C, Piroddi IM,et al. Noninvasive ventilation for acute respiratory failure due to community-acquired pneumonia: a concise review and update. Commu Acquired Infect, 2015, 2(2): 46-50.
10.	Peto L, Nadjm B, Horby P,et al. The bacterial aetiology of adult community-acquired pneumonia in Asia: a systematic review. Trans R Soc Trop Med Hyg, 2014, 108(6): 326-337.
11.	解鄭良, 郭璐, 劉躍建. 重癥社區獲得性肺炎死亡患者的臨床特征及死亡預測因素分析. 華西醫學, 2015, 30(9): 1618-1621.
12.	歐陽星鑫, 周艷華, 晏娟, 等. 重癥監護病房腫瘤患者呼吸機相關性肺炎的干預效果分析. 華西醫學, 2016, 31(11): 1807-1810.
13.	Correia MD, Refaat AH, Takashi H,et al. Evidence-based recommendations for addressing malnutrition in health care: an updated strategy from the feed M.E. Global study group. J Am Med Dir Assoc, 2014, 15(8): 544-550.
14.	周華, 許媛. 危重癥病人營養支持指南解讀. 中國實用外科雜志, 2008, 28(11): 925-928.
15.	王傳湄, 徐麗丹, 江美芳, 等. 老年重癥肺炎病人腸內外營養治療的效果觀察. 臨床肺科雜志, 2009, 14(11): 1470-1471.
16.	王遠方, 唐洪波, 張偉, 等. 老年重癥肺炎的腸內外營養支持療法探討. 現代預防醫學, 2012, 39(19): 4958-4959.

1. Lim WS, Baudouin SV, George RC,et al. BTS guidelines for the management of community acquired pneumonia in adults: update 2009. Thorax, 2009, 64(Suppl 3): 1-55.
2. 王玉光, 孫兆家. 375例慢性腦出血后肺炎患者病原菌分布及其預后影響因素分析. 中國生化藥物雜志, 2014, 34(2): 157-159.
3. Mandell LA, Wunderink RG, Anzueto A,et al. Infectious diseases society of America/American thoracic society consensus guidelines on the management of community-acquired pneumonia in adults. Clin Infect Dis, 2007, 44(Suppl 2): S27-S72.
4. Mercadal-Orfila G, Lluch-Taltavull J, Campillo-Artero C. Association between nutritional risk based on the NRS-2002 test and hospital morbidity and mortality. Nutr Hosp, 2012, 27(4): 1248-1254.
5. 李挺. 提高老年肺炎診斷的臨床分析. 中華實用醫藥雜志, 2004, 4(10): 413.
6. Calleja Fernández A, Vidal Casariego A, Ballesteros Pomar MD. Comparative study of total energy expenditure estimated by sense wear armband and harris-benedictequation in healthy ambulatory population; utility in clincal practice. Nutr Hosp, 2012, 27(4): 1244-1247.
7. 周曉云. 大環內酯類抗菌藥物在下呼吸道感染患者中的應用效果. 華西醫學, 2015, 30(7): 1205-1208.
8. Chatha N, Fortin D, Bosma KJ. Management of necrotizing pneumonia and pulmonary gangrene: a case series and review of the literature. Can Respir J, 2014, 21(4): 239-245.
9. Nicolini A, Cilloniz C, Piroddi IM,et al. Noninvasive ventilation for acute respiratory failure due to community-acquired pneumonia: a concise review and update. Commu Acquired Infect, 2015, 2(2): 46-50.
10. Peto L, Nadjm B, Horby P,et al. The bacterial aetiology of adult community-acquired pneumonia in Asia: a systematic review. Trans R Soc Trop Med Hyg, 2014, 108(6): 326-337.
11. 解鄭良, 郭璐, 劉躍建. 重癥社區獲得性肺炎死亡患者的臨床特征及死亡預測因素分析. 華西醫學, 2015, 30(9): 1618-1621.
12. 歐陽星鑫, 周艷華, 晏娟, 等. 重癥監護病房腫瘤患者呼吸機相關性肺炎的干預效果分析. 華西醫學, 2016, 31(11): 1807-1810.
13. Correia MD, Refaat AH, Takashi H,et al. Evidence-based recommendations for addressing malnutrition in health care: an updated strategy from the feed M.E. Global study group. J Am Med Dir Assoc, 2014, 15(8): 544-550.
14. 周華, 許媛. 危重癥病人營養支持指南解讀. 中國實用外科雜志, 2008, 28(11): 925-928.
15. 王傳湄, 徐麗丹, 江美芳, 等. 老年重癥肺炎病人腸內外營養治療的效果觀察. 臨床肺科雜志, 2009, 14(11): 1470-1471.
16. 王遠方, 唐洪波, 張偉, 等. 老年重癥肺炎的腸內外營養支持療法探討. 現代預防醫學, 2012, 39(19): 4958-4959.

West China Medical Journal

Effect of different nutritional support on the prognosis of severe community-acquired pneumonia

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content