Forensic Analysis on Cases of Infant Death after Vaccination_West China Medical Journal

Authors：

 ZHUHai-biao ¹ , LIUYuan ¹ , ZHUPeng ² , YANGYu ¹ , CHENXia-meng ¹ ,  GUANPeng ¹

1. Department of Forensic Pathology, West China School of Preclinical and Forensic Science, Sichuan University, Chengdu, Sichuan 610041, P. R. China;
2. Technology Department of the People's Procuratorate, Chengdu, Sichuan 610041, P. R. China;

Corresponding?author：

GUANPeng, Email: guanpengcn@yahoo.com

Keywords：

Infant; Suspected adverse events following immunization; Forensic autopsy; Cause of death; Coupling disease

DOI：

10.7507/1002-0179.20150548

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Objective To explore the common causes and the clinical pathological characteristics of infant death which occurred after vaccination. Methods The study retrospectively analyzed the data of 13 cases of infant death occurring after vaccination from January 2009 to September 2014 in West China Medico-legal Expertise Center. Results Among the 13 cases of infant death, 12 were dead from lethal respiratory system and cardiovascular system diseases, 1 from mechanic asphyxia caused by milk intake. All cases were coupling disease death and had no direct correlation with vaccination. Conclusion Systematic and comprehensive forensic pathological examination is helpful to clarify the cause of death, reveal the relationship between vaccination and the cause of death, and contribute to proper processing of such incidents.

Citation： ZHUHai-biao, LIUYuan, ZHUPeng, YANGYu, CHENXia-meng, GUANPeng. Forensic Analysis on Cases of Infant Death after Vaccination. West China Medical Journal, 2015, 30(10): 1919-1923. doi: 10.7507/1002-0179.20150548 Copy

1.	王富珍, 崔富強, 劉大衛, 等. 接種乙型肝炎疫苗后10例嬰兒死亡的疑似預防接種異常反應分析[J]. 中國疫苗和免疫, 2009, 15(1): 52-57.
2.	張敏. 新生兒家長計劃免疫的知曉率及需求調查分析[J]. 中外醫學研究, 2012, 10(14):55-56.
3.	許賢芳, 龔培玉. 注射乙腦疫苗過敏反應一例[J]. 解剖與臨床, 1997, 2(4):191.
4.	張延煬, 路明霞, 王燕, 等. 1993~2013年疫苗接種不良反應的文獻分析[J]. 中國生物制品學雜志, 2014, 27(4):548-549.
5.	王長雙, 路明霞, 張肖肖, 等. 河南省2010-2011年疑似預防接種異常反應死亡病例分析[J]. 當代醫學, 2014, 20(7):162-164.
6.	Zhou W, Pool V, Iskander JK, et al. Surveillance for safety after immunization:Vaccine Adverse Event Reporting System (VAERS)—— United States, 1991-2001[J]. MMWR Surveill Summ, 2003, 52(1):1-24.
7.	常利民, 劉大衛, 李克莉, 等. 全國2008~2010年接種疫苗后過敏性休克監測結果分析[J]. 中國疫苗和免疫, 2012, 18(5):398-401, 446.
8.	Silvers LE, Ellenberg SS, Wise RP, et al. The epidemiology of fatalities reported to the vaccine adverse event reporting system 1990-1997[J]. Pharmacoepidemiol Drug Saf, 2001, 10(4):279-285.
9.	Kim JH, Cho HY, Hennessey KA, et al. Adverse events following immunization (AEFI) with the novel influenza A (H₁N₁) 2009 vaccine: ndings from the National registry of all vaccine recipients and AEFI and the passive surveillance system in South Korea[J]. Jpn J Infect Dis, 2012, 65(2):99-104.
10.	胡家瑜, 黃卓英, 陶黎納, 等. 上海市2006~2008年預防接種后死亡病例分析[J]. 中國疫苗和免疫, 2010, 16(2):165-168.
11.	李欣影, 宋鳳卿, 練巧玲, 等. 532例5歲以下住院兒童主要死因分析[J]. 北華大學學報:自然科學版, 2008, 9(4):350-352.
12.	吳興龍, 黃佳佳, 譚娜, 等. 嬰幼兒58例死亡原因尸檢病理和醫療糾紛原因分析[J]. 中華實用兒科臨床雜志, 2014, 29(6):431-435.
13.	華秀鳳. 41例新生兒死亡分析與對策[J]. 青海醫藥雜志, 2001, 31(1):39-40.
14.	李克莉, 武文娣, 劉大衛, 等. 猝死與流行性感冒疫苗接種后死亡綜述[J]. 中國疫苗和免疫, 2010, 16(3):270-273.
15.	杜彥克. 同時接種百白破聯合疫苗和脊髓灰質炎疫苗后偶合窒息死亡1例[J]. 中國計劃免疫, 2007, 13(4):297.
16.	蔣純艷, 謝和清, 陳娟, 等. 1310例甲型H₁N₁流感裂解疫苗接種的安全性觀察及干預措施[J]. 中國現代醫學雜志, 2010, 20(23): 3598-3602.
17.	方義湖, 張可麗, 于海勝, 等. 202例醫療糾紛的病理尸檢的回顧分析[J]. 浙江大學學報:醫學版, 2013, 42(4):456-460.

1. 王富珍, 崔富強, 劉大衛, 等. 接種乙型肝炎疫苗后10例嬰兒死亡的疑似預防接種異常反應分析[J]. 中國疫苗和免疫, 2009, 15(1): 52-57.
2. 張敏. 新生兒家長計劃免疫的知曉率及需求調查分析[J]. 中外醫學研究, 2012, 10(14):55-56.
3. 許賢芳, 龔培玉. 注射乙腦疫苗過敏反應一例[J]. 解剖與臨床, 1997, 2(4):191.
4. 張延煬, 路明霞, 王燕, 等. 1993~2013年疫苗接種不良反應的文獻分析[J]. 中國生物制品學雜志, 2014, 27(4):548-549.
5. 王長雙, 路明霞, 張肖肖, 等. 河南省2010-2011年疑似預防接種異常反應死亡病例分析[J]. 當代醫學, 2014, 20(7):162-164.
6. Zhou W, Pool V, Iskander JK, et al. Surveillance for safety after immunization:Vaccine Adverse Event Reporting System (VAERS)—— United States, 1991-2001[J]. MMWR Surveill Summ, 2003, 52(1):1-24.
7. 常利民, 劉大衛, 李克莉, 等. 全國2008~2010年接種疫苗后過敏性休克監測結果分析[J]. 中國疫苗和免疫, 2012, 18(5):398-401, 446.
8. Silvers LE, Ellenberg SS, Wise RP, et al. The epidemiology of fatalities reported to the vaccine adverse event reporting system 1990-1997[J]. Pharmacoepidemiol Drug Saf, 2001, 10(4):279-285.
9. Kim JH, Cho HY, Hennessey KA, et al. Adverse events following immunization (AEFI) with the novel influenza A (H₁N₁) 2009 vaccine: ndings from the National registry of all vaccine recipients and AEFI and the passive surveillance system in South Korea[J]. Jpn J Infect Dis, 2012, 65(2):99-104.
10. 胡家瑜, 黃卓英, 陶黎納, 等. 上海市2006~2008年預防接種后死亡病例分析[J]. 中國疫苗和免疫, 2010, 16(2):165-168.
11. 李欣影, 宋鳳卿, 練巧玲, 等. 532例5歲以下住院兒童主要死因分析[J]. 北華大學學報:自然科學版, 2008, 9(4):350-352.
12. 吳興龍, 黃佳佳, 譚娜, 等. 嬰幼兒58例死亡原因尸檢病理和醫療糾紛原因分析[J]. 中華實用兒科臨床雜志, 2014, 29(6):431-435.
13. 華秀鳳. 41例新生兒死亡分析與對策[J]. 青海醫藥雜志, 2001, 31(1):39-40.
14. 李克莉, 武文娣, 劉大衛, 等. 猝死與流行性感冒疫苗接種后死亡綜述[J]. 中國疫苗和免疫, 2010, 16(3):270-273.
15. 杜彥克. 同時接種百白破聯合疫苗和脊髓灰質炎疫苗后偶合窒息死亡1例[J]. 中國計劃免疫, 2007, 13(4):297.
16. 蔣純艷, 謝和清, 陳娟, 等. 1310例甲型H₁N₁流感裂解疫苗接種的安全性觀察及干預措施[J]. 中國現代醫學雜志, 2010, 20(23): 3598-3602.
17. 方義湖, 張可麗, 于海勝, 等. 202例醫療糾紛的病理尸檢的回顧分析[J]. 浙江大學學報:醫學版, 2013, 42(4):456-460.

West China Medical Journal

Forensic Analysis on Cases of Infant Death after Vaccination

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