性別及性腺激素對睡眠影響的臨床研究進展_West China Medical Journal

Authors：

 付聰 , 謝晨 ,  陳云飛

上海中醫藥大學附屬岳陽中西醫結合醫院中心實驗室（上海 200347）;

Corresponding?author：

陳云飛, Email: icyf1968@163.com

Keywords：

性別; 性腺激素; 生理睡眠; 慢性失眠; 臨床研究

DOI：

10.7507/1002-0179.20150166

Video：

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Abstract Full text Figures/Tables Video References Cited by

睡眠和生理節律的機制已得到廣泛研究，其異常存在著性別差異，因此針對不同性別失眠患者的臨床研究對提高臨床療效有著重要作用和意義。現綜合近5年國內外相關臨床文獻，從性別和性腺激素角度探討其對生理睡眠和慢性失眠的影響。

Citation： 付聰, 謝晨, 陳云飛. 性別及性腺激素對睡眠影響的臨床研究進展. West China Medical Journal, 2015, 30(3): 577-581. doi: 10.7507/1002-0179.20150166 Copy

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1. Bolge SC, Joish VN, Balkrishnan R, et al. Burden of chronic sleep maintenance insomnia characterized by nighttime awakenings[J]. Popul Health Manag, 2010, 13(1):15-20.
2. 孫卉, 張田. 589名徐州市大學生睡眠質量及其相關因素分析[J]. 中國校醫, 2009, 23(2):160-162.
3. 李燕芬, 葉小華, 徐英. 中國大學生睡眠質量性別差異的Meta分析[J]. 中國學校衛生, 2012, 33(1):74-77.
4. 潘敬菊, 譚曉東, 謝朝軍. 大學生睡眠質量和相關影響因素調查[J]. 中國熱帶醫學, 2007, 7(5):845-847.
5. 鄒枝玲, 黃希庭, 楊勛, 等. 大學生睡眠質量與睡眠衛生意識現狀[J]. 西南大學學報:人文社會科學版, 2006, 32(3):7-11.
6. 姜丹寧. 沈陽市大學生睡眠質量及影響因素分析[J]. 中國公共衛生, 2008, 24(9):1130-1131.
7. 王生平. 高原地區大學生睡眠質量調查[J]. 衛生職業教育, 2009, 27(22):106.
8. 章勁松. 在校大學生睡眠質量及其影響因素研究[D]. 武漢:武漢科技大學, 2012:8-10.
9. 戚東桂, 劉榮, 吳曉茜, 等. 大學生睡眠質量及其影響因素調查[J]. 現代預防醫學, 2007, 34(5):875-877.
10. 張林, 刁娟. 大學生睡眠質量及其相關影響因素的研究[J]. 中國臨床心理學雜志, 2006, 14(5):515-517.
11. 曹炳健, 曹輝, 白吉可. 石河子大學在校大學生睡眠質量與心理健康狀況的調查研究[J]. 中國健康心理學雜志, 2009, 17(10):1225-1227.
12. 趙崇蓮, 鄭涌. 大學生睡眠質量與A型行為模式的相關研究[J]. 西南大學學報:社會科學版, 2008, 34(6):7-10.
13. 鄒宗峰, 方小衡, 劉茂玲, 等. 某醫藥院校大學生睡眠質量與考試焦慮的關系研究[J]. 中國健康心理學雜志, 2010, 18(6):697-700.
14. 尹輝, 王麗娜, 袁崗. 醫學院校大學生睡眠質量及影響因素分析[J]. 中國公共衛生, 2008, 24(11):1346.
15. Mccall C, Mccall WV. Objective vs. subjective measurements of sleep in depressed insomniacs:first night effect or reverse first night effect?[J]. J Clin Sleep Med, 2012, 8(1):59-65.
16. Van den Berg JF, Miedema HM, Tulen JH, et al. Sex differences in subjective and actigraphic sleep measures:a population-based study of elderly persons[J]. Sleep, 2009, 32(10):1367-1375.
17. Kuriyama K, Mishima K, Soshi T, et al. Effects of sex differences and regulation of the sleep-wake cycle on aversive memory encoding[J]. Neurosci Res, 2011, 70(1):104-110.
18. 潘集陽, 馬文彬, 張繼輝, 等. 慢性原發性失眠患者主客觀睡眠質量差異及相關因素[J]. 中國神經精神疾病雜志, 2007, 33(2):69-72.
19. Giménez S, Romero S, Gich I, et al. Sex differences in sleep after a single oral morning dose of olanzapine in healthy volunteers[J]. Hum Psychopharmacol, 2011, 26(7):498-507.
20. Dijk DJ, James LM, Peters S, et al. Sex differences and the effect of gaboxadol and zolpidem on EEG power spectra in NREM and REM sleep[J]. J Psychopharmacol, 2010, 24(11):1613-1618.
21. Paul KN, Turek FW, Kryger MH. Influence of sex on sleep regulatory mechanisms[J]. J Womens Health (Larchmt), 2008, 17(7):1201-1208.
22. Duffy JF, Cain SW, Chang AM, et al. Sex difference in the near-24-hour intrinsic period of the human circadian timing system[J]. Proc Natl Acad Sci USA, 2011, 108(Suppl 3):15602-15608.
23. Toh KL, Jones CR, He Y, et al. An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome[J]. Science, 2001, 291(5506):1040-1043.
24. Ebisawa T, Uchiyama M, Kajimura N, et al. Association of structural polymorphisms in the human period 3 gene with delayed sleep phase syndrome[J]. EMBO Rep, 2001, 2(4):342-346.
25. Archer SN, Robillard DL, Skene DJ, et al. A length polymorphism in the circadian clock gene Per3 is linked to delayed sleep phase syndrome and extreme diurnal preference[J]. Sleep, 2003, 26(4):413-415.
26. Dijk DJ, Beersma DG, Bloem GM. Sex differences in the sleep EEG of young adults:visual scoring and spectral analysis[J]. Sleep, 1989, 12(6):500-507.
27. Ehlers CL, Kupfer DJ. Slow-wave sleep:do young adult men and women age differently?[J]. J Sleep Res, 1997, 6(3):211-215.
28. Armitage R, Hoffmann RF. Sleep EEG, depression and gender[J]. Sleep Med Rev, 2001, 5(3):237-246.
29. Armitage R, Thompson SC, Thompson S, et al. Sex differences in slow wave activity in response to sleep deprivation[J]. Sleep Res Online, 2001, 4:33-41.
30. Carter JR, Durocher JJ, Larson RA, et al. Sympathetic neural responses to 24-hour sleep deprivation in humans:sex differences[J]. Am J Physiol Heart Circ Physiol, 2012, 302(10):H1991-H1997.
31. Pawlyk AC, Morrison AR, Ross RJ. Stress-induced changes in sleep in rodents:models and mechanisms[J]. Neurosci Biobehav Rev, 2008, 32(1):99-117.
32. Buysse DJ, Germain A, Hall ML, et al. EEG spectral analysis in primary insomnia:NREM period effects and sex differences[J]. Sleep, 2008, 31(12):1673-1682.
33. 姚華, 鄒媛. 新疆高校3288名管理干部及高級知識分子健康調查研究[J]. 新疆醫科大學學報, 2011, 34(12):1402-1405.
34. Green MJ, Espie CA, Hunt K, et al. The longitudinal course of insomnia symptoms:inequalities by sex and occupational class among two different age cohorts followed for 20 years in the West of Scotland[J]. Sleep, 2012, 35(6):815-823.
35. 梁政亭, 朱奇, 張星平, 等. 失眠癥PSG睡眠結構參數男女性別差異比較[J]. 新疆醫科大學學報, 2013, 36(6):796-798.
36. Richards A, Metzler TJ, Ruoff LM, et al. Sex differences in objective measures of sleep in post-traumatic stress disorder and healthy control subjects[J]. J Sleep Res, 2013, 22(6):679-687.
37. Kobayashi I, Cowdin N, Mellman T. One's sex, sleep, and post-traumatic stress disorder[J]. Biol Sex Differ, 2012, 3(1):29.
38. Born L, Shea A, Steiner M. The Roots of depression in adolescent girls:is menarche the key?[J]. Curr Psychiatry Rep, 2002, 4(6):449-460.
39. Zhang B, Wing YK. Sex differences in insomnia:a meta-analysis[J]. Sleep, 2006, 29(1):85-93.
40. Thordstein M, Lofgren N, Flisberg AA, et al. Sex differences in electrocortical activity in human neonates[J]. Neuroreport, 2006, 17(11):1165-1168.
41. Menna-Barreto L, Montagner H, Soussignan R, et al. The sleep/wake cycle in 4-to 14-month-old children:general aspects and sex differences[J]. Braz J Med Biol Res, 1989, 22(1):103-106.
42. Nagy E, Loveland KA, Orvos H, et al. Gender-related physiologic differences in human neonates and the greater vulnerability of males to developmental brain disorders[J]. J Gend Specif Med, 2001, 4(1):41-49.
43. Sadeh A, Dark I, Vohr BR. Newborns' sleep-wake patterns:the role of maternal, delivery and infant factors[J]. Early Hum Dev, 1996, 44(2):113-126.
44. Hoppenbrouwers T, Hodgman JE, Rybine D, et al. Sleep architecture in term and preterm infants beyond the neonatal period:the influence of gestational age, steroids, and ventilatory support[J]. Sleep, 2005, 28(11):1428-1436.
45. Campbell IG, Grimm KJ, De Bie E, et al. Sex, puberty, and the timing of sleep EEG measured adolescent brain maturation[J]. Proc Natl Acad Sci USA, 2012, 109(15):5740-5743.
46. Genzel L, Kiefer T, Renner L, et al. Sex and modulatory menstrual cycle effects on sleep related memory consolidation[J]. Psychoneuroendocrinology, 2012, 37(7):987-998.
47. Olds T, Blunden S, Petkov J, et al. The relationships between sex, age, geography and time in bed in adolescents. A meta-analysis of data from 23 countries[J]. Sleep Med Rev, 2010, 14(6):371-378.
48. Tonetti L, Fabbri M, Natale V. Sex difference in sleep-time preference and sleep need:a cross-sectional survey among Italian pre-adolescents, adolescents, and adults[J]. Chronobiol Int, 2008, 25(5):745-759.
49. Johnson EO, Roth T, Schultz L, et al. Epidemiology of DSM-Ⅳinsomnia in adolescence:lifetime prevalence, chronicity, and an emergent gender difference[J]. Pediatrics, 2006, 117(2):E₂47-E₂56.
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