An Investigation of Cardiovascular Risk Factors in Pre-diabetes Patients in Rural Areas of Chengdu City_West China Medical Journal

Authors：

 LIAOXiao-yang ¹ , WANGWei-wen ² , WUJia ¹ , ZHOUXin-ping ¹ , WANGNa ¹ , ZHAOQian ¹ ,  LIShuang-qing

1. Department of General Practice, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;
2. Department of Neurology, Chengdu Military General Hospital, Chengdu, Sichuan 610083, P. R. China;

Corresponding?author：

LIShuang-qing, Email: 1259594471@qq.com

Keywords：

Pre-diabetes; Cardiovascular risk factors; Rural area; Glucose tolerance test

DOI：

10.7507/1002-0179.20150079

Video：

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Objective To investigate the prevalence of impaired glucose regulation (IGR) and IGR combined with cardiovascular risk factors in rural areas of Chengdu City. Methods From February to October 2010, we randomly sampled 1 016 patients in a rural community 100 kilometers away from the city center as the study subjects. The investigation was carried out by using questionnaire survey, physical examination and laboratory tests. The standard 75 g oral glucose tolerance test was used. Results A total of 1 016 subjects were investigated, among whom there were 431 males and 585 females with an average age of 56 years old. Of these subjects, 333 were diagnosed to have IGR with a rate of 32.77% (333/1 016). The age-adjusted standardized prevalence of pre-diabetes in rural areas in Chengdu was 32.52% (336/1 016), and the male and female prevalence were respectively 30.63% (132/431) and 34.36% (201/585) without significant difference (χ²=1.569，P=0.210). Impaired glucose tolerance (IGT) was the most common type of glycometabolism abnormality. Women had a significantly higher prevalence of IGT than men. In IGR population, major cardiovascular risk factors were overweight and obesity (40.8%), high low density lipoprotein cholesterol (38.4%), high triglyceride (30.3%), hypertension (23.7%), smoking (24.3%), and drinking alcohol (23.7%). The stratified analysis showed that the prevalence of overweight, obesity and low high density lipoprotein cholesterol in female was significantly higher than that in males, while the prevalence of smoking and drinking alcohol was significantly higher in males. Conclusion In rural areas, the prevalence of pre-diabetes is high and complicated with multiple cardiovascular risk factors.

Citation： LIAOXiao-yang, WANGWei-wen, WUJia, ZHOUXin-ping, WANGNa, ZHAOQian, LIShuang-qing. An Investigation of Cardiovascular Risk Factors in Pre-diabetes Patients in Rural Areas of Chengdu City. West China Medical Journal, 2015, 30(2): 250-253. doi: 10.7507/1002-0179.20150079 Copy

1.	朱海清, 楊文英. 亞洲人群糖尿病患病情況:現狀和未來[J]. 中華流行病學雜志, 2011, 32(11):1065-1067.
2.	中華醫學會糖尿病學分會. 中國2型糖尿病防治指南(2010年版)[J]. 中國糖尿病雜志, 2012, 20(1):81-117.
3.	胡大一. 糖尿病患者多重心血管危險因素綜合管理中國專家共識[J]. 心腦血管病防治, 2012, 12(4):261-266.
4.	World Health Organization. Package of essential noncommunicable (PEN) disease interventions for primary health care in low-resource settings[M]. Geneva:World Health Organization, 2010.
5.	中國高血壓防治指南修訂委員會. 中國高血壓防治指南[J]. 高血壓雜志, 2000, 39(2):7-16.
6.	中國成人血脂異常防治指南制訂聯合委員會. 中國成人血脂異常防治指南[J]. 中華心血管病雜志, 2007, 35(5):390-419.
7.	中國肥胖問題工作組數據匯總分析協作組. 我國成人體重指數和腰圍對相關疾病危險因素異常的預測價值:適宜體重指數和腰圍切點的研究[J]. 中華流行病學雜志, 2002, 23(1):10-15.
8.	李栩, 馮波, 倪亞芳, 等. 不同診斷標準對上海市浦東新區40歲以上社區人群糖代謝類型分布的影響[J]. 上海醫學, 2006, 29(5):283-285.
9.	冀黎明, 張春槐, 柴軍土, 等. 浙江省慈溪市部分城鄉40歲以上人群糖尿病的患病率調查[J]. 江西醫藥, 2007, 42(5):402-404.
10.	鄒欣, 張婭東, 朱風元, 等. 福建省三明社區糖尿病及糖調節受損患病率現況調查[J]. 中國醫學文摘:老年醫學分冊, 2009, 2(1):32-34.
11.	呂春雷. 杭州城區居民糖代謝異常的流行病學調查[J]. 中國現代醫生, 2012, 50(24):10-11, 14.
12.	王帥, 岳仁宋, 龔光明, 等. 農村中老年居民2型糖尿病影響因素分析[J]. 中國公共衛生, 2011, 27(7):819-820.
13.	武陽豐, 馬冠生, 胡永華, 等. 中國居民的超重和肥胖流行現狀[J]. 中華預防醫學雜志, 2005, 39(5):316-320.
14.	李強. 肥胖促進2型糖尿病發生的研究進展[J]. 臨床內科雜志, 2012, 29(3):152-154.
15.	姚冬娥, 吳慧芳, 儲德節. 農村地區糖尿病患者體質指數與血脂、血糖及血壓間的關系[J]. 中華全科醫學, 2012, 10(9):1434-1435.
16.	張聞宇, 張素華, 任偉, 等. 重慶地區NGT、IGR、糖尿病血脂異常的特征[J]. 重慶醫科大學學報, 2005, 30(5):704-706.
17.	DeFronzo RA. Insulin resistance, lipotoxicity, type 2 diabetes and atherosclerosis:the missing links. The Claude Bernard Lecture 2009[J]. Diabetologia, 2010, 53(7):1270-1287.
18.	陳宇紅, 張翼飛, 詹維偉, 等. 早期動脈硬化與不同糖耐量狀態的相關性[J]. 中華內分泌代謝雜志, 2005, 21(4):353-356.
19.	Ginsberg HN, Elam MB, Lovato LC, et al. Effects of combination lipid therapy in type 2 diabetes mellitus[J]. N Engl J Med, 2010, 362(17):1563-1574.
20.	Li G, Zhang P, Wang J, et al. The long-term effect of lifestyle interventions to prevent diabetes in the China Da Qing Diabetes Prevention Study:a 20-year follow-up study[J]. Lancet, 2008, 371(9626):1783-1789.
21.	戰義強, 余金明, 胡大一, 等. 北京居民糖尿病患病率及相關知識行為調查[J]. 中國公共衛生, 2012, 28(1):19-21.
22.	徐濤, 李衛, 胡泊, 等. 中國11省市成年人吸煙和被動吸煙情況調查[J]. 中國慢性病預防與控制, 2010, 18(3):229-230.

1. 朱海清, 楊文英. 亞洲人群糖尿病患病情況:現狀和未來[J]. 中華流行病學雜志, 2011, 32(11):1065-1067.
2. 中華醫學會糖尿病學分會. 中國2型糖尿病防治指南(2010年版)[J]. 中國糖尿病雜志, 2012, 20(1):81-117.
3. 胡大一. 糖尿病患者多重心血管危險因素綜合管理中國專家共識[J]. 心腦血管病防治, 2012, 12(4):261-266.
4. World Health Organization. Package of essential noncommunicable (PEN) disease interventions for primary health care in low-resource settings[M]. Geneva:World Health Organization, 2010.
5. 中國高血壓防治指南修訂委員會. 中國高血壓防治指南[J]. 高血壓雜志, 2000, 39(2):7-16.
6. 中國成人血脂異常防治指南制訂聯合委員會. 中國成人血脂異常防治指南[J]. 中華心血管病雜志, 2007, 35(5):390-419.
7. 中國肥胖問題工作組數據匯總分析協作組. 我國成人體重指數和腰圍對相關疾病危險因素異常的預測價值:適宜體重指數和腰圍切點的研究[J]. 中華流行病學雜志, 2002, 23(1):10-15.
8. 李栩, 馮波, 倪亞芳, 等. 不同診斷標準對上海市浦東新區40歲以上社區人群糖代謝類型分布的影響[J]. 上海醫學, 2006, 29(5):283-285.
9. 冀黎明, 張春槐, 柴軍土, 等. 浙江省慈溪市部分城鄉40歲以上人群糖尿病的患病率調查[J]. 江西醫藥, 2007, 42(5):402-404.
10. 鄒欣, 張婭東, 朱風元, 等. 福建省三明社區糖尿病及糖調節受損患病率現況調查[J]. 中國醫學文摘:老年醫學分冊, 2009, 2(1):32-34.
11. 呂春雷. 杭州城區居民糖代謝異常的流行病學調查[J]. 中國現代醫生, 2012, 50(24):10-11, 14.
12. 王帥, 岳仁宋, 龔光明, 等. 農村中老年居民2型糖尿病影響因素分析[J]. 中國公共衛生, 2011, 27(7):819-820.
13. 武陽豐, 馬冠生, 胡永華, 等. 中國居民的超重和肥胖流行現狀[J]. 中華預防醫學雜志, 2005, 39(5):316-320.
14. 李強. 肥胖促進2型糖尿病發生的研究進展[J]. 臨床內科雜志, 2012, 29(3):152-154.
15. 姚冬娥, 吳慧芳, 儲德節. 農村地區糖尿病患者體質指數與血脂、血糖及血壓間的關系[J]. 中華全科醫學, 2012, 10(9):1434-1435.
16. 張聞宇, 張素華, 任偉, 等. 重慶地區NGT、IGR、糖尿病血脂異常的特征[J]. 重慶醫科大學學報, 2005, 30(5):704-706.
17. DeFronzo RA. Insulin resistance, lipotoxicity, type 2 diabetes and atherosclerosis:the missing links. The Claude Bernard Lecture 2009[J]. Diabetologia, 2010, 53(7):1270-1287.
18. 陳宇紅, 張翼飛, 詹維偉, 等. 早期動脈硬化與不同糖耐量狀態的相關性[J]. 中華內分泌代謝雜志, 2005, 21(4):353-356.
19. Ginsberg HN, Elam MB, Lovato LC, et al. Effects of combination lipid therapy in type 2 diabetes mellitus[J]. N Engl J Med, 2010, 362(17):1563-1574.
20. Li G, Zhang P, Wang J, et al. The long-term effect of lifestyle interventions to prevent diabetes in the China Da Qing Diabetes Prevention Study:a 20-year follow-up study[J]. Lancet, 2008, 371(9626):1783-1789.
21. 戰義強, 余金明, 胡大一, 等. 北京居民糖尿病患病率及相關知識行為調查[J]. 中國公共衛生, 2012, 28(1):19-21.
22. 徐濤, 李衛, 胡泊, 等. 中國11省市成年人吸煙和被動吸煙情況調查[J]. 中國慢性病預防與控制, 2010, 18(3):229-230.

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An Investigation of Cardiovascular Risk Factors in Pre-diabetes Patients in Rural Areas of Chengdu City

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