以靜脈血栓栓塞為首發表現的肺癌_West China Medical Journal

Authors：

 蒲曉雯 , 尹成紅 , 黃蓉

東莞市厚街醫院呼吸內科（廣東東莞，523945）;

Corresponding?author：

Keywords：

靜脈血栓栓塞; 肺癌; 首發表現

DOI：

10.7507/1002-0179.20140691

Video：

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目的探討以靜脈血栓栓塞（TVE）為首發表現的肺癌臨床特點，及其對肺癌診斷的意義。方法回顧性分析2009年－2012年期間以VTE為首發表現的6例肺癌患者的臨床資料，均以上、下肢深靜脈血栓形成收住院，其中合并肺栓塞2例。均在住院或隨訪期間診斷肺癌，其中腺癌5例，小細胞癌1例。結果隨訪期間4例1年內死亡，2例存活。結論臨床遇及原發性靜脈血栓形成患者應積極尋找病因，對抗凝治療效果不佳者要警惕惡性腫瘤，及時完善腫瘤相關檢查，以早期診治。

Citation： 蒲曉雯, 尹成紅, 黃蓉. 以靜脈血栓栓塞為首發表現的肺癌. West China Medical Journal, 2014, 29(12): 2286-2287. doi: 10.7507/1002-0179.20140691 Copy

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1. 中華醫學會呼吸病學會. 肺血栓栓塞癥的診斷與治療指南(草案)[J]. 中華結核和呼吸雜志, 2001, 24(5):6-11.
2. Sallah S, Wan JY, Nquyen NP. Venous thrombosis in patients with solid tumors:determination of frequency and characteristics[J]. Thromb Haemost, 2002, 87(4):575-579.
3. 陸慰萱, 李龍蕓, 高巖, 等. 血栓栓塞性疾病與肺癌[J]. 中華結核和呼吸雜志, 2000, 23(7):15-17.
4. Pruemer J. Prevalence, causes, and impact of cancer-associated thrombosis[J]. Am J Health Syst Pharm, 2005, 62(22 Suppl 5):S4-S6.
5. 陳文慧, 王辰. 惡性腫瘤與血栓性疾病[J]. 中國醫刊, 2008, 43(1):14-15.
6. Khorana AA, Francis CW, Culakova E, et al. Frequency, risk factors, and trends for venous thromboembolism among hospitalized cancer patients[J]. Cancer, 2007, 110(10):2339-2346.
7. Akl EA, Kamath G, Kim SY, et al. Oral anticoagulation for prolonging survival in patients with cancer[J]. Cochrane Database Syst Rev, 2007, 18(2):CD006466.
8. 孫景娟, 王旭, 王策, 等. 肺癌合并靜脈血栓栓塞的危險因素[J]. 中國老年學雜志, 2012, 32(10):2026-2028.
9. Baron JA, Gridley G, Weiderpass E, et al. Venous thromboembolism and cancer[J]. Lancet, 1998, 351(9109):1077-1080.
10. Lee JE, Kim HR, Lee SM, et al. Clinical characteristics of pulmonary embolism with underlying malignancy[J]. Korean J Intern Med, 2010, 25(1):66-70.
11. Murchison JT, Wylie L, Stockton DL. Excess risk of cancer in patients with primary venous thromboembolism:a National, population-based cohort study[J]. Br J Cancer, 2004, 91(1):92-95.

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以靜脈血栓栓塞為首發表現的肺癌

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