Testing and Analysis of Antigen and Antibody for Children's Immunization Program Targeted Diseases_West China Medical Journal

Authors：

 HEWei-feng , LIQiu-lian , LUOYue-juan

Yongning District Center for Disease Control and Prevention, Nanning, Guangxi 530200, P. R. China;

Corresponding?author：

Keywords：

Children; Immune planning for the disease; Antigen; Antibody; Testing

DOI：

10.7507/1002-0179.20140629

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Objective To summarize the results of testing and analysis of antigen and antibody for diseases under the frame of children's immunization program, in order to know the effects of prevention and control of such diseases in this area. Methods A total of 150 children from each of the 5 communities or administrative villages in Yongning District of Nanning City were selected for our survey between January and December 2012. The 150 children were composed of 30 children (residents, 1-6 years old, 5 children from each different age group) randomly selected from each of the four directions (east, south, west and north) and the mid-area of each community or village. The serum samples were collected to analyze the existence of poliomyelitis antibody, measles antibody, hepatitis B surface antigen (HBsAg), hepatitis B surface antibody (HBsAb), and diphtheria antibody. Results Among the 150 school-age children, antibody immune qualified rate was high for hepatitis B (HBV) antigen, in which the HBsAg immune qualified rate was 99.3%, and HBsAb immune qualified rate was 88.0%, showing no significant difference between boys and girls (P>0.05). All poliomyelitis Ⅰ, Ⅱ, and Ⅲ antibody positive rates reached 100.0%. Measles antibody test results were also satisfying for each age group, among whom the 2 and 3 year-olds reached a positive rate of the highest, 100%, and the 1, 4, 5, and 6 year-old children had a measles antibody positive rate of 96.0%, 84.0%, 88.0%, and 96.0%, respectively. The positive rate for diphtheria antibody was 100%. Conclusion The antibody and antigen detection and analysis results for the children's immune program targeted diseases are generally satisfying in this area. Especially, the prevention of poliomyelitis and diphtheria is the best. However, prevention of HBV and measles is not as good. Therefore, tracking immunization coverage, promoting public awareness on immune planning, actively participating in the vaccination of children should be enhanced for further disease prevention.

Citation： HEWei-feng, LIQiu-lian, LUOYue-juan. Testing and Analysis of Antigen and Antibody for Children's Immunization Program Targeted Diseases. West China Medical Journal, 2014, 29(11): 2092-2095. doi: 10.7507/1002-0179.20140629 Copy

1.	蔡琳, 方瓊, 王永剛, 等. 2010年深圳市福田區兒童免疫接種率調查[J]. 職業與健康, 2012, 28(14):1761-1762, 1765.
2.	申劍波, 張建中, 宋承聲, 等. 西雙版納州1~15歲兒童脊灰、百日咳、白喉、破傷風、麻疹和乙肝抗體水平監測結果[J]. 職業與健康, 2012, 28(1):68-70.
3.	竇俊娟. 天津市漢沽區兒童卡介苗免疫接種效果分析[J]. 職業與健康, 2011, 27(17):1987-1988.
4.	李鳳英, 徐藝, 劉軍禮, 等. 2009-2010年咸陽市健康兒童乙型肝炎抗體水平監測結果[J]. 職業與健康, 2012, 28(14):1742-1743.
5.	陳曉微, 胡斌. 永嘉縣2006-2010年兒童免疫規劃接種率調查[J]. 浙江預防醫學, 2012, 24(4):30-31.
6.	侯新月, 李培勇. 瑪納斯縣學齡前兒童乙肝表面抗體水平及表面抗原攜帶狀況調查分析[J]. 中國衛生檢驗雜志, 2012, 22(9):2179-2180.
7.	Murhekar MV, Bitragunta S, Hutin Y, et al. Immunization coverage and immunity to diphtheria and tetanus among children in Hyderabad, India[J]. J Infect, 2009, 58(3):191-196.
8.	呂惠榮, 郭金香. 2009-2011年信陽市麻疹實驗室監測結果分析[J]. 職業與健康, 2012, 28(19):2383-2385.
9.	鄭紅茹, 劉青戀, 漆琪, 等. 2009-2011年四川省兒童免疫規劃接種率抽樣調查[J]. 預防醫學情報雜志, 2014, 30(1):35-39.
10.	劉明禹, 楊霞, 周雅媗, 等. 2011年大連市高新區免疫規劃疫苗接種率調查[J]. 預防醫學情報雜志, 2012, 28(4):309-311.
11.	張勝利, 劉志霞, 曹勝文, 等. 蘭州市紅古區健康人群麻疹、脊髓灰質炎、風疹抗體水平監測分析[J]. 疾病預防控制通報, 2013, 28(2):64-65.
12.	蔡廣俊, 韋陽, 李傳道, 等. 臨泉縣2009年脊髓灰質炎和麻疹抗體水平調查分析[J]. 安徽預防醫學雜志, 2011, 17(6):413-415.
13.	張俊杰. 共和縣2010年-2012年兒童免疫規劃4種疫苗免疫效果監測分析[J]. 青海醫藥雜志, 2014, 44(1):49-50.
14.	祁慶賀, 哈杰, 范學彬. 2012年蛟河市14周歲以下人群麻疹、脊髓灰質炎抗體水平的監測[J]. 中國生物制品學雜志, 2013, 26(12):1812-1813.
15.	張俊杰, 楊恒丹, 崔振鐸, 等. 平頂山市2010年麻疹疫苗強化免疫活動的分析[J]. 中國生物制品學雜志, 2012, 25(12):1676-1679.
16.	曾鴻, 黃志雄, 張桂玲, 等. 佛山市南海區免疫規劃兒童免疫水平的監測與分析[J]. 中國生物制品學雜志, 2012, 25(3):349-352.
17.	曾昭長, 曾雪霞, 莫少雄, 等. 海南省2010年兒童白喉疫苗免疫效果分析[J]. 中國公共衛生, 2012, 28(6):851.
18.	林寶妮, 方瓊, 曹麗, 等. 2009-2011年福田區兒童免疫接種率調查[J]. 實用預防醫學, 2012, 19(3):385-386.

1. 蔡琳, 方瓊, 王永剛, 等. 2010年深圳市福田區兒童免疫接種率調查[J]. 職業與健康, 2012, 28(14):1761-1762, 1765.
2. 申劍波, 張建中, 宋承聲, 等. 西雙版納州1~15歲兒童脊灰、百日咳、白喉、破傷風、麻疹和乙肝抗體水平監測結果[J]. 職業與健康, 2012, 28(1):68-70.
3. 竇俊娟. 天津市漢沽區兒童卡介苗免疫接種效果分析[J]. 職業與健康, 2011, 27(17):1987-1988.
4. 李鳳英, 徐藝, 劉軍禮, 等. 2009-2010年咸陽市健康兒童乙型肝炎抗體水平監測結果[J]. 職業與健康, 2012, 28(14):1742-1743.
5. 陳曉微, 胡斌. 永嘉縣2006-2010年兒童免疫規劃接種率調查[J]. 浙江預防醫學, 2012, 24(4):30-31.
6. 侯新月, 李培勇. 瑪納斯縣學齡前兒童乙肝表面抗體水平及表面抗原攜帶狀況調查分析[J]. 中國衛生檢驗雜志, 2012, 22(9):2179-2180.
7. Murhekar MV, Bitragunta S, Hutin Y, et al. Immunization coverage and immunity to diphtheria and tetanus among children in Hyderabad, India[J]. J Infect, 2009, 58(3):191-196.
8. 呂惠榮, 郭金香. 2009-2011年信陽市麻疹實驗室監測結果分析[J]. 職業與健康, 2012, 28(19):2383-2385.
9. 鄭紅茹, 劉青戀, 漆琪, 等. 2009-2011年四川省兒童免疫規劃接種率抽樣調查[J]. 預防醫學情報雜志, 2014, 30(1):35-39.
10. 劉明禹, 楊霞, 周雅媗, 等. 2011年大連市高新區免疫規劃疫苗接種率調查[J]. 預防醫學情報雜志, 2012, 28(4):309-311.
11. 張勝利, 劉志霞, 曹勝文, 等. 蘭州市紅古區健康人群麻疹、脊髓灰質炎、風疹抗體水平監測分析[J]. 疾病預防控制通報, 2013, 28(2):64-65.
12. 蔡廣俊, 韋陽, 李傳道, 等. 臨泉縣2009年脊髓灰質炎和麻疹抗體水平調查分析[J]. 安徽預防醫學雜志, 2011, 17(6):413-415.
13. 張俊杰. 共和縣2010年-2012年兒童免疫規劃4種疫苗免疫效果監測分析[J]. 青海醫藥雜志, 2014, 44(1):49-50.
14. 祁慶賀, 哈杰, 范學彬. 2012年蛟河市14周歲以下人群麻疹、脊髓灰質炎抗體水平的監測[J]. 中國生物制品學雜志, 2013, 26(12):1812-1813.
15. 張俊杰, 楊恒丹, 崔振鐸, 等. 平頂山市2010年麻疹疫苗強化免疫活動的分析[J]. 中國生物制品學雜志, 2012, 25(12):1676-1679.
16. 曾鴻, 黃志雄, 張桂玲, 等. 佛山市南海區免疫規劃兒童免疫水平的監測與分析[J]. 中國生物制品學雜志, 2012, 25(3):349-352.
17. 曾昭長, 曾雪霞, 莫少雄, 等. 海南省2010年兒童白喉疫苗免疫效果分析[J]. 中國公共衛生, 2012, 28(6):851.
18. 林寶妮, 方瓊, 曹麗, 等. 2009-2011年福田區兒童免疫接種率調查[J]. 實用預防醫學, 2012, 19(3):385-386.

Previous Article
Analysis on the Cause of Varicose Veins with Deep Vein Angiography
Next Article
Survey and Analysis of Health Related Knowledge in 816 Cadres

West China Medical Journal

Testing and Analysis of Antigen and Antibody for Children's Immunization Program Targeted Diseases

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content