Correlation between Ultrasonographic Features of Patients with HIV/AIDS Combined with Chronic Viral Hepatitis and CD4<sup>+</sup>T Lymphocyte Count_West China Medical Journal

Authors：

 CAOFen ¹ , YEQing ²

1. Department of Ultrasonography, the Infectious Disease Hospital of Chengdu City, Chengdu, Sichuan 610061, P. R. China;
2. Department of TCM, the Infectious Disease Hospital of Chengdu City, Chengdu, Sichuan 610061, P. R. China;

Corresponding?author：

Keywords：

HIV/AIDS combined with chronic viral hepatitis; Ultrasonic inspection; Intrahepatic vein and splenic vein; CD4⁺T lymphocyte count

DOI：

10.7507/1002-0179.20140625

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Objective To investigate the ultrasonic changes of hepatic veins and splenic veins during various immune stages with different CD4⁺T lymphocyte count. Methods Fifty AIDS/HIV patients with chronic viral hepatitis treated between January 2010 and October 2013 were designated as the case group, and another 50 patients with simple chronic viral hepatitis were regarded as the controls. For patients in the case group, we observed their ultrasonic changes of hepatic and splenic veins during various immune stages with different CD4⁺T lymphocyte count. The results of observation and clinical laboratory analysis were compared. Results Abnormal ultrasonic changes were detected in the liver in various immune stages based on the CD4⁺T lymphocyte count, and the main manifestations of these changes included unclear portal and splenic vein distal direction, wide diameter, slowed blood flow velocity, and disappearance of fluctuations of blood flow spectrum; and unclear hepatic vein distal direction, low and three-phase, and negative blood flow spectrum with the disappearance of windows were also detected. There were no statistical differences between the case group and the control group when the CD4⁺T cell count was over 300/mm³, and a few indexes were significantly different when the CD4⁺T cell count was between 100 and 200/mm³. However, the differences of almost all indexes were significant when the CD4⁺T cell count was below 100/mm³. Conclusion Patients with HIV/AIDS combined with chronic viral hepatitis have ultrasonographic abnormalities of intrahepatic and splenic veins, which is more obvious as the CD4⁺T cell count declines. Overall consideration of intrahepatic vein and splenic vein ultrasonic indicators helps clinical assessment of disease development in patients with HIV/AIDS combined with chronic viral hepatitis.

Citation： CAOFen, YEQing. Correlation between Ultrasonographic Features of Patients with HIV/AIDS Combined with Chronic Viral Hepatitis and CD4⁺T Lymphocyte Count. West China Medical Journal, 2014, 29(11): 2077-2080. doi: 10.7507/1002-0179.20140625 Copy

1.	Hoffmann C, Rockstroh JK, Kamps BS. 艾滋病診療學[M]. 張福杰, 尚紅, 吳昊, 等, 譯. 北京:人民衛生出版社, 2009:315-330.
2.	中華醫學會傳染病與寄生蟲病分會, 中華醫學會肝病分會. 病毒性肝炎防治方案[J]. 中華肝臟雜志, 2008, 8(6):324-329.
3.	郭萬學. 超聲醫學[M]. 6版. 北京:人民軍醫出版社, 2011:795-796.
4.	唐杰, 賈容緯. 腹部和外周血管彩色多普勒診斷學[M]. 北京:人民衛生出版社, 1992:97-99.
5.	許寶寧, 呂群. 預防控制艾滋病健康教育[J]. 應用預防醫學, 2008. 14(增刊):15-18.
6.	鄭穎, 孟凡坤, 張海英, 等. 艾滋病腹部超聲的聲像圖改變[J]. 中國超聲診斷雜志, 2004, 5(5):358-360.
7.	曹韻貞. 艾滋病臨床診斷、治療及護理[M]. 北京:人民衛生出版社, 2002:148-149.
8.	張媛媛, 陳恩強, 李紅, 等. 人類免疫缺陷病毒感染77例臨床特點分析[J]. 臨床薈萃, 2008, 23(23):1722-1724.
9.	福軍亮, 王福生. HIV和丙型肝炎病毒合并感染的臨床特點和治療的研究進展[J]. 中國艾滋病性病, 2005, 11(2):153-155.
10.	張新力, 陳重, 蘇穎, 等. 慢性乙型及丙型病毒性肝炎的超聲表現與病理對照分析[J]. 中華實驗和臨床病毒學雜志, 2003, 17(4):337-338.
11.	孟繁坤, 徐策, 張海英, 等. 對慢性病毒性肝炎超聲診斷指標的再探討[J]. 中國超聲診斷雜志, 2002, 3(8):592-594.
12.	莫讓輝, 李論, 陸鵬. 艾滋病合并乙、丙型病毒性肝炎96例分析[J]. 中國熱帶醫學, 2008, 8(10):1745-1746.
13.	謝峰, 沈俐, 萬紅, 等. 慢性肝炎超聲血流成像定量指標與肝功能損害程度的相關性研究[J]. 臨床超聲醫學雜志, 2008, 10(4):229-231.
14.	曹芬, 葉慶. HIV/AIDS合并慢性肝炎肝臟聲像圖特征與CD4⁺T淋巴細胞數相關性的研究[J]. 華西醫學, 2014, 29(1):80-82.

1. Hoffmann C, Rockstroh JK, Kamps BS. 艾滋病診療學[M]. 張福杰, 尚紅, 吳昊, 等, 譯. 北京:人民衛生出版社, 2009:315-330.
2. 中華醫學會傳染病與寄生蟲病分會, 中華醫學會肝病分會. 病毒性肝炎防治方案[J]. 中華肝臟雜志, 2008, 8(6):324-329.
3. 郭萬學. 超聲醫學[M]. 6版. 北京:人民軍醫出版社, 2011:795-796.
4. 唐杰, 賈容緯. 腹部和外周血管彩色多普勒診斷學[M]. 北京:人民衛生出版社, 1992:97-99.
5. 許寶寧, 呂群. 預防控制艾滋病健康教育[J]. 應用預防醫學, 2008. 14(增刊):15-18.
6. 鄭穎, 孟凡坤, 張海英, 等. 艾滋病腹部超聲的聲像圖改變[J]. 中國超聲診斷雜志, 2004, 5(5):358-360.
7. 曹韻貞. 艾滋病臨床診斷、治療及護理[M]. 北京:人民衛生出版社, 2002:148-149.
8. 張媛媛, 陳恩強, 李紅, 等. 人類免疫缺陷病毒感染77例臨床特點分析[J]. 臨床薈萃, 2008, 23(23):1722-1724.
9. 福軍亮, 王福生. HIV和丙型肝炎病毒合并感染的臨床特點和治療的研究進展[J]. 中國艾滋病性病, 2005, 11(2):153-155.
10. 張新力, 陳重, 蘇穎, 等. 慢性乙型及丙型病毒性肝炎的超聲表現與病理對照分析[J]. 中華實驗和臨床病毒學雜志, 2003, 17(4):337-338.
11. 孟繁坤, 徐策, 張海英, 等. 對慢性病毒性肝炎超聲診斷指標的再探討[J]. 中國超聲診斷雜志, 2002, 3(8):592-594.
12. 莫讓輝, 李論, 陸鵬. 艾滋病合并乙、丙型病毒性肝炎96例分析[J]. 中國熱帶醫學, 2008, 8(10):1745-1746.
13. 謝峰, 沈俐, 萬紅, 等. 慢性肝炎超聲血流成像定量指標與肝功能損害程度的相關性研究[J]. 臨床超聲醫學雜志, 2008, 10(4):229-231.
14. 曹芬, 葉慶. HIV/AIDS合并慢性肝炎肝臟聲像圖特征與CD4⁺T淋巴細胞數相關性的研究[J]. 華西醫學, 2014, 29(1):80-82.

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Correlation between Ultrasonographic Features of Patients with HIV/AIDS Combined with Chronic Viral Hepatitis and CD4⁺T Lymphocyte Count

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West China Medical Journal

Correlation between Ultrasonographic Features of Patients with HIV/AIDS Combined with Chronic Viral Hepatitis and CD4+T Lymphocyte Count

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Correlation between Ultrasonographic Features of Patients with HIV/AIDS Combined with Chronic Viral Hepatitis and CD4⁺T Lymphocyte Count