Influence of Intervention through Diets and Exercises on Controlling the Blood Glucose of Patients with Gestational Diabetes Mellitus_West China Medical Journal

Authors：

 LILing-ling ¹ , YANTing ¹ , LIUJun ² ,  HEQing ¹

1. Department of Clinical Nutrition, the Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510655, P. R. China;
2. Department of Statistics, the Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510655, P. R. China;

Corresponding?author：

HEQing, Email: heqingdoc@163.com

Keywords：

Diabetes mellitus; Pregnancy; Dietary guidance; Exercise therapy

DOI：

10.7507/1002-0179.20140623

Video：

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Objective To investigate the effect of behavior intervention through diets and exercises on blood glucose controlling in patients with gestational diabetes mellitus (GDM), and to provide the basis for GDM therapy. Methods A total of 116 patients with GDM diagnosed and treated in the Sixth Affiliated Hospital of Sun Yat-sen University between March 2011 and December 2012 were taken as our study objects, including 72 patients in the study group and 44 patients in the control group, based on their will. For patients in the study group, we carried out behavior interventions through diets and exercises, including dietary guidance, giving pamphlet and formulating exercise plan, while for patients in the control group, we only gave them oral guidance and publicity materials. The same questionnaire was used to collect all the patients' information. Follow-up was done once in every 3 days, and rechecking was performed 2 weeks later. The results of oral glucose tolerance test and the rate of pathoglycemia were compared in these groups before and after intervention. Results The fasting blood glucose, 1- and 2-hour blood glucose were lowered after the behavior intervention in the study group (P<0.05), which were also significantly lower than the control group (P<0.05). Fasting blood glucose, 1- and 2-hour pathoglycemia was significantly lower in the study group than that in the control group and that before intervention (P<0.05). Conclusion Combination of diets and exercises can control levels of blood glucose in GDM patients, and is an important therapy for GDM.

Citation： LILing-ling, YANTing, LIUJun, HEQing. Influence of Intervention through Diets and Exercises on Controlling the Blood Glucose of Patients with Gestational Diabetes Mellitus. West China Medical Journal, 2014, 29(11): 2069-2072. doi: 10.7507/1002-0179.20140623 Copy

1.	莫萍, 吳惠芳, 楊振玲, 等. 妊娠期糖尿病篩查450例結果分析[J]. 中國婦幼保健, 2004, 19(7):15-16.
2.	張燕軍, 馬文君, 肖本熙, 等. 糖代謝異常孕婦的營養狀況及血糖的膳食影響因素分析[J]. 中國全科醫學, 2008, 11(23):2113-2115.
3.	International Association of Diabetes and Pregnancy Study Groups Consensus Panel, Metzger BE, Gabbe SG, et al. International association of diabetes and pregnancy study groups recommendations on the diagnosis and classification of hyperglycemia in pregnancy[J]. Diabetes Care, 2010, 33(3):676-682.
4.	Zhang F, Dong L, Zhang CP, et al. Increasing prevalence of gestational diabetes mellitus in Chinese women from 1999 to 2008[J]. Diabet Med, 2011, 28(6):652-657.
5.	Chu SY, Callaghan WM, Kim SY, et al. Maternal obesity and risk of gestational diabetes mellitus[J]. Diabetes Care, 2007, 30(8):2070-2076.
6.	馬冠生, 李艷平, 武陽豐, 等. 1992至2002年間中國居民超重率和肥胖率的變化[J]. 中華預防醫學雜志, 2005, 39(5):17-21.
7.	Matuszek B, Burska A, Leszczyńska-Gorzelak B, et al. Comparative analysis of adiponectin isoform distribution in pregnant women with gestational diabetes mellitus and after delivery[J]. Acta Obstet Gynecol Scand, 2013, 92(8):951-959.
8.	董玉英, 孫云燕, 楊悅旻, 等. 應用胰島素泵短期強化治療妊娠期糖尿病療效分析[J]. 中國實用婦科與產科雜志, 2008, 24(10):755-758.
9.	鄒阮敏, 李云云, 包影, 等. 妊娠期糖尿病早期診斷及治療對妊娠結局的影響[J]. 醫學研究雜志, 2011, 40(9):84-87.
10.	Moreno-Castilla C, Hernandez M, Bergua M, et al. Low-carbohydrate diet for the treatment of gestational diabetes mellitus:a randomized controlled trial[J]. Diabetes Care, 2013, 36(8):2233-2238.
11.	潘玥, 劉巧, 朱紹密. 妊娠期糖尿病胰島素治療的臨床分析[J]. 中國計劃生育和婦產科, 2011, 3(6):57-60.
12.	Reader D, Splett P, Gunderson EP. Impact of gestational diabetes mellitus practice guidelines implemented by registered dietitians[J]. J Am Diet Assoc, 2006, 106(9):1426-1433.
13.	Louie JC, Brand-Miller JC, Carbohydrates MR, et al. Carbohydrates, glycemic index, and pregnancy outcomes in gestational diabetes[J]. Curr Diab Rep, 2013, 13(1):6-11.
14.	Zhang C, Liu S, Solomon CG, et al. Dietary fiber intake, dietary glycemic load, and the risk for gestational diabetes mellitus[J]. Diabetes Care, 2006, 29(10):2223-2230.
15.	葛茜, 林江, 張寶風, 等. 食物GI與交換份用于2型糖尿病營養治療觀察[J]. 臨床和實驗醫學雜志, 2008, 7(12):5-6.
16.	孫建琴, 沈秀華, 宗敏, 等. 基于血糖負荷概念的食物交換份在糖尿病營養治療中的應用[J]. 營養學報, 2006, 28(1):27-31.
17.	Zhang C, Schulze MB, Solomon CG, et al. A prospective study of dietary patterns, meat intake and the risk of gestational diabetes mellitus[J]. Diabetologia, 2006, 49(11):2604-2613.
18.	Afaghi A, Ghanei L, Ziaee A. Effect of low glycemic load diet with and without wheat bran on glucose control in gestational diabetes mellitus:a randomized trial[J]. Indian J Endocrinol Metab, 2013, 17(4):689-692.
19.	Barakat R, Cordero Y, Coteron J, et al. Exercise during pregnancy improves maternal glucose screen at 24-28 weeks:a randomised controlled trial[J]. Br J Sports Med, 2012, 46(9):656-661.
20.	Retnakaran R, Qi Y, Sermer M, et al. Pre-gravid physical activity and reduced risk of glucose intolerance in pregnancy:the role of insulin sensitivity[J]. Clin Endocrinol (Oxf), 2009, 70(4):615-622.
21.	楊慧霞, 徐先明, 孫偉杰. 妊娠合并糖尿病臨床實踐指南[M]. 北京:人民衛生出版社, 2008:189-196.

1. 莫萍, 吳惠芳, 楊振玲, 等. 妊娠期糖尿病篩查450例結果分析[J]. 中國婦幼保健, 2004, 19(7):15-16.
2. 張燕軍, 馬文君, 肖本熙, 等. 糖代謝異常孕婦的營養狀況及血糖的膳食影響因素分析[J]. 中國全科醫學, 2008, 11(23):2113-2115.
3. International Association of Diabetes and Pregnancy Study Groups Consensus Panel, Metzger BE, Gabbe SG, et al. International association of diabetes and pregnancy study groups recommendations on the diagnosis and classification of hyperglycemia in pregnancy[J]. Diabetes Care, 2010, 33(3):676-682.
4. Zhang F, Dong L, Zhang CP, et al. Increasing prevalence of gestational diabetes mellitus in Chinese women from 1999 to 2008[J]. Diabet Med, 2011, 28(6):652-657.
5. Chu SY, Callaghan WM, Kim SY, et al. Maternal obesity and risk of gestational diabetes mellitus[J]. Diabetes Care, 2007, 30(8):2070-2076.
6. 馬冠生, 李艷平, 武陽豐, 等. 1992至2002年間中國居民超重率和肥胖率的變化[J]. 中華預防醫學雜志, 2005, 39(5):17-21.
7. Matuszek B, Burska A, Leszczyńska-Gorzelak B, et al. Comparative analysis of adiponectin isoform distribution in pregnant women with gestational diabetes mellitus and after delivery[J]. Acta Obstet Gynecol Scand, 2013, 92(8):951-959.
8. 董玉英, 孫云燕, 楊悅旻, 等. 應用胰島素泵短期強化治療妊娠期糖尿病療效分析[J]. 中國實用婦科與產科雜志, 2008, 24(10):755-758.
9. 鄒阮敏, 李云云, 包影, 等. 妊娠期糖尿病早期診斷及治療對妊娠結局的影響[J]. 醫學研究雜志, 2011, 40(9):84-87.
10. Moreno-Castilla C, Hernandez M, Bergua M, et al. Low-carbohydrate diet for the treatment of gestational diabetes mellitus:a randomized controlled trial[J]. Diabetes Care, 2013, 36(8):2233-2238.
11. 潘玥, 劉巧, 朱紹密. 妊娠期糖尿病胰島素治療的臨床分析[J]. 中國計劃生育和婦產科, 2011, 3(6):57-60.
12. Reader D, Splett P, Gunderson EP. Impact of gestational diabetes mellitus practice guidelines implemented by registered dietitians[J]. J Am Diet Assoc, 2006, 106(9):1426-1433.
13. Louie JC, Brand-Miller JC, Carbohydrates MR, et al. Carbohydrates, glycemic index, and pregnancy outcomes in gestational diabetes[J]. Curr Diab Rep, 2013, 13(1):6-11.
14. Zhang C, Liu S, Solomon CG, et al. Dietary fiber intake, dietary glycemic load, and the risk for gestational diabetes mellitus[J]. Diabetes Care, 2006, 29(10):2223-2230.
15. 葛茜, 林江, 張寶風, 等. 食物GI與交換份用于2型糖尿病營養治療觀察[J]. 臨床和實驗醫學雜志, 2008, 7(12):5-6.
16. 孫建琴, 沈秀華, 宗敏, 等. 基于血糖負荷概念的食物交換份在糖尿病營養治療中的應用[J]. 營養學報, 2006, 28(1):27-31.
17. Zhang C, Schulze MB, Solomon CG, et al. A prospective study of dietary patterns, meat intake and the risk of gestational diabetes mellitus[J]. Diabetologia, 2006, 49(11):2604-2613.
18. Afaghi A, Ghanei L, Ziaee A. Effect of low glycemic load diet with and without wheat bran on glucose control in gestational diabetes mellitus:a randomized trial[J]. Indian J Endocrinol Metab, 2013, 17(4):689-692.
19. Barakat R, Cordero Y, Coteron J, et al. Exercise during pregnancy improves maternal glucose screen at 24-28 weeks:a randomised controlled trial[J]. Br J Sports Med, 2012, 46(9):656-661.
20. Retnakaran R, Qi Y, Sermer M, et al. Pre-gravid physical activity and reduced risk of glucose intolerance in pregnancy:the role of insulin sensitivity[J]. Clin Endocrinol (Oxf), 2009, 70(4):615-622.
21. 楊慧霞, 徐先明, 孫偉杰. 妊娠合并糖尿病臨床實踐指南[M]. 北京:人民衛生出版社, 2008:189-196.

West China Medical Journal

Influence of Intervention through Diets and Exercises on Controlling the Blood Glucose of Patients with Gestational Diabetes Mellitus

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