Ultrasound and Pathological Analysis of Intrauterine Residual Tissue in Patients with Vaginal Bleeding after Drug Abortion_West China Medical Journal

Authors：

 YAOAi-jing ¹ , GAODa-wei ²

1. Department of Gynaecology and Obstetrics, the Eighth Hospital of Tangshan, Tangshan, Hebei 063000, P. R. China;
2. the Woman and Children Hospital of Tangshan, Tangshan, Hebei, 063000, P. R. China;

Corresponding?author：

Keywords：

Prolonged bleeding; Intrauterine residue; Ultrasound; Pathology

DOI：

10.7507/1002-0179.20140280

Video：

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Abstract Full text Figures/Tables Video References Cited by

Objective To examine the intrauterine residual tissue in patients with prolonged vaginal bleeding after drug abortion by both B-ultrasound and pathology through cleaning the remnant of uterine, in order to investigate the relationship between prolonged vaginal bleeding after medical abortion with mifepristone and the residual tissues (decidua/villi). Methods Between June and December 2011, 144 patients with vaginal bleeding after medical abortion were involved in the study. B-ultrasound and pathology through cleaning the remnant of uterine were adopted to study the residual tissue respectively. Results Based on the ultrasound results, the difference in residual tissues was statistically significant between patients with bleeding for 15 days or shorter and patients with bleeding for more than 15 days (P<0.05). The pathological results showed that the difference in decidua and villi on the residual tissues was not statistically significant between patients with bleeding for 15 days or shorter and patients with bleeding for more than 15 days (P>0.05). Conclusion After drug abortion, the prolonged vaginal bleeding was correlated with intrauterine residual tissues, and was not correlated with whether the residual tissue was villi or decidua.

Citation： YAOAi-jing, GAODa-wei. Ultrasound and Pathological Analysis of Intrauterine Residual Tissue in Patients with Vaginal Bleeding after Drug Abortion. West China Medical Journal, 2014, 29(5): 925-927. doi: 10.7507/1002-0179.20140280 Copy

1.	L?keland M, Iversen OE, Dahle GS, et al. Medical abortion at 63 to 90 days of gestation[J]. Obstet Gynecol, 2010, 115(5):962-968.
2.	樂杰. 婦產科學[M]. 北京:人民衛生出版社, 2008:374-375.
3.	韓向陽, 孫敬霞, 韓燕燕. 藥物流產并發癥的種類處理和預防[J]. 中國實用婦科與產科雜志, 2000, 16(10):590-592.
4.	顧向應, 李麗, 范慶春, 等. 早孕藥物流產時米非司酮劑量和不同作用時間對蛻膜類固醇受體表達的影響[J]. 生殖與避孕, 2008, 28(8):467-470, 476.
5.	Im A, Appleman LJ. Mifepristone:pharmacology and clinical impact in reproductive medicine, endocrinology and oncology[J]. Expert Opin Pharmacother, 2010, 11(3):481-488.
6.	Kapp NP, Ngo TD. Cervical preparation for first trimester surgical abortion[J]. Obstet Gynecol, 2010, 115(5):1075-1076.
7.	翁梨駒. 米非司酮配伍前列腺素終止妊娠8~12周的流產問題[J]. 中國實用婦科與產科雜志, 2000, 16(10):9-11.
8.	賴文瑤. 藥物流產和人工流產對再次妊娠各期并發癥影響的比較[J]. 廣東醫學院學報, 2002, 20(1):53-57.
9.	Angela D. The efficacy and tolerance of mifepristone and prostaglandin in termination of pregnancy of less than 63 days gestation; UK Multicentre Study-final results[J]. Contraception, 1997, 55(1):1-5.
10.	張艷, 高爾生, 朱虔兮, 等. 米非司酮藥物流產與繼后妊娠產后出血的研究[J]. 中國實用婦科與產科雜志, 2008, 24(5):351-353.
11.	鄭波. 兩例藥物流產大出血中縮宮素應用不當分析[J]. 中國實用醫藥, 2012, 7(16):167-168.
12.	童傳良, 莊留琪. 藥物流產的安全性與評價[J]. 中國實用婦科與產科雜志, 2000, 16(10):588-590.
13.	張云竹, 于燕, 吳燕虹. 藥物流產后出血的原因中西醫研究進展[J]. 遼寧中醫藥大學學報, 2008, 10(12):179-181.
14.	桑國衛, 翁黎駒, 邵慶翔, 等. 不同劑量米非司酮和米索前列醇終止早孕的臨床研究[J]. 中華婦產科雜志, 1994, 29(12):735-738, 763.
15.	李瑞珍, 王振海, 吳瑞芳, 等. 米非司酮配伍米索前列醇抗早孕蛻膜與絨毛細胞凋亡及其調控基因的研究[J]. 中華婦產科雜志, 1999, 34(5):24-26.

1. L?keland M, Iversen OE, Dahle GS, et al. Medical abortion at 63 to 90 days of gestation[J]. Obstet Gynecol, 2010, 115(5):962-968.
2. 樂杰. 婦產科學[M]. 北京:人民衛生出版社, 2008:374-375.
3. 韓向陽, 孫敬霞, 韓燕燕. 藥物流產并發癥的種類處理和預防[J]. 中國實用婦科與產科雜志, 2000, 16(10):590-592.
4. 顧向應, 李麗, 范慶春, 等. 早孕藥物流產時米非司酮劑量和不同作用時間對蛻膜類固醇受體表達的影響[J]. 生殖與避孕, 2008, 28(8):467-470, 476.
5. Im A, Appleman LJ. Mifepristone:pharmacology and clinical impact in reproductive medicine, endocrinology and oncology[J]. Expert Opin Pharmacother, 2010, 11(3):481-488.
6. Kapp NP, Ngo TD. Cervical preparation for first trimester surgical abortion[J]. Obstet Gynecol, 2010, 115(5):1075-1076.
7. 翁梨駒. 米非司酮配伍前列腺素終止妊娠8~12周的流產問題[J]. 中國實用婦科與產科雜志, 2000, 16(10):9-11.
8. 賴文瑤. 藥物流產和人工流產對再次妊娠各期并發癥影響的比較[J]. 廣東醫學院學報, 2002, 20(1):53-57.
9. Angela D. The efficacy and tolerance of mifepristone and prostaglandin in termination of pregnancy of less than 63 days gestation; UK Multicentre Study-final results[J]. Contraception, 1997, 55(1):1-5.
10. 張艷, 高爾生, 朱虔兮, 等. 米非司酮藥物流產與繼后妊娠產后出血的研究[J]. 中國實用婦科與產科雜志, 2008, 24(5):351-353.
11. 鄭波. 兩例藥物流產大出血中縮宮素應用不當分析[J]. 中國實用醫藥, 2012, 7(16):167-168.
12. 童傳良, 莊留琪. 藥物流產的安全性與評價[J]. 中國實用婦科與產科雜志, 2000, 16(10):588-590.
13. 張云竹, 于燕, 吳燕虹. 藥物流產后出血的原因中西醫研究進展[J]. 遼寧中醫藥大學學報, 2008, 10(12):179-181.
14. 桑國衛, 翁黎駒, 邵慶翔, 等. 不同劑量米非司酮和米索前列醇終止早孕的臨床研究[J]. 中華婦產科雜志, 1994, 29(12):735-738, 763.
15. 李瑞珍, 王振海, 吳瑞芳, 等. 米非司酮配伍米索前列醇抗早孕蛻膜與絨毛細胞凋亡及其調控基因的研究[J]. 中華婦產科雜志, 1999, 34(5):24-26.

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West China Medical Journal

Ultrasound and Pathological Analysis of Intrauterine Residual Tissue in Patients with Vaginal Bleeding after Drug Abortion

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