Risk Factors for Carotid Stenosis in Patients with Ischemic Cerebrovascular Disease_West China Medical Journal

Authors：

 GONGSi-yin , ZHOUMu-ke , ZHENGHong-bo , JIANGYi ,  HELi

Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;

Corresponding?author：

HELi, Email: heli2003new@126.com

Keywords：

Ischemic cerebrovascular disease; Carotid stenosis; Risk factor; Digital subtraction angiography

DOI：

10.7507/1002-0179.20140064

Video：

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Objective To analysis the risk factors for carotid stenosis in patients with ischemic cerebrovascular disease based on digital subtraction angiography. Methods A total of 312 patients diagnosed with ischemic cerebrovascular disease who underwent digital subtraction angiography from June 2011 to September 2013 were selected.The risk factors of carotid stenosis were analysised by multivariate logistic regression analysis. Results In 312 patients,271 were with cerebral infarction and 41 were transient ischemic attack patients.There were 149 patients in carotid stenosis group (stenosis degree ≥50%) and 163 patients in control group (stenosis degree<50%).The age (OR=1.037,P=0.000) and coronary heart disease (OR=4.121,P=0.001) were independent risk factors of carotid stenosis with ischemic cerebrovascular disease. Conclusion Carotid stenosis is common in ischemic cerebrovascular disease.Age and coronary heart disease were the independent risk factors.The recognition and control of these risk factors are in favor of secondary prevention of ischemic cerebrovascular disease.

Citation： GONGSi-yin, ZHOUMu-ke, ZHENGHong-bo, JIANGYi, HELi. Risk Factors for Carotid Stenosis in Patients with Ischemic Cerebrovascular Disease. West China Medical Journal, 2014, 29(2): 210-213. doi: 10.7507/1002-0179.20140064 Copy

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1. 饒明俐.《中國腦血管病防治指南》摘要(一)[J].中風與神經疾病雜志,2005,22(5):388-393.
2. Zhu CZ,Norris JW.Role of carotid stenosis in ischemic stroke[J].Stroke,1990,21(8):1131-1134.
3. 鄭宇,華揚,凌晨,等.頸動脈狹窄的危險因素與缺血性卒中的相關性分析[J].中國超聲診斷雜志,2004,5(1):4-6.
4. 華揚,鄭宇,凌晨,等.動脈粥樣硬化危險因素與頸動脈狹窄和缺血性卒中的相關性[J].中國腦血管病雜志,2004,1(2):69-72.
5. Chang CH,Chang YJ,Lee TH,et al.Risk factors of carotid stenosis in first-ever ischemic stroke in Taiwan:a hospital-based study[J].Acta Neurol Taiwan,2006,15(4):237-243.
6. Dharmasaroja PA,Intharakham K.Risk factors for carotid stenosis in Thai patients with ischemic stroke/TIA[J].Angiology,2010,61(8):789-792.
7. Buskens E,Nederkoorn PJ,Buijs-Van Der Woude T,et al.Imaging of carotid arteries in symptomatic patients:cost-effectiveness of diagnostic strategies[J].Radiology,2004,233(1):101-112.
8. 中華神經科學會.中華神經外科學會.各類腦血管疾病診斷要點[J].中華神經科雜志,1996,29(6):379-380.
9. Madden KP,Karanjia PN,Adams HP,et al.Accuracy of initial stroke subtype diagnosis in the TOAST study.Trial of ORG 10172 in Acute Stroke Treatment[J].Neurology,1995,45(11):1975-1979.
10. North American Symptomatic Carotid Endarterectomy Trial Collaborators.Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis[J].N Engl J Med,1991,325(7):445-453.
11. 周衡,王擁軍,王素香,等.急性缺血性腦卒中的TOAST亞型分析[J].中華內科雜志,2004,43(7):495-498.
12. 許曉輝,許予明,談頌,等.缺血性卒中改良的TOAST分型與OCSP分型關系的研究[J].中國實用內科雜志,2008,28(7):538-539.
13. 王淦楠,王瑤,張晶,等.缺血性腦卒中及其TOAST分型相關危險因素分析[J].江蘇醫藥,2011,37(16):1898-1900.
14. 顧力華,陳斌,魏丹霞,等.急性腦梗死TOAST分型與危險因素的關系[J].實用心腦肺血管病雜志,2013,21(2):51-52.
15. 宋麗,李婉婷,韓杰.缺血性腦卒中TOAST分型及其危險因素、復發分析[J].中國醫藥科學,2013,3(5):17-19.
16. Gutierrez J,Koch S,Dong C,et al.Racial and ethnic disparities in stroke subtypes:a multiethnic sample of patients with stroke[J/OL].Neurol Sci,(2013-10-15)[2013-12-01].http://www.ncbi.nlm.nih.gov/pubmed/24122024.
17. 黃磊.缺血性腦血管病血管狹窄的評估[D].上海:復旦大學,2008.
18. 侯昊明.缺血性腦血管病患者腦動脈狹窄特點的研究[D].南京:第一軍醫大學,2006.
19. 丁建平,華揚,凌晨,等.缺血性腦卒中患者動脈粥樣硬化分布的臨床研究[J].中國現代神經疾病雜志,2006,6(4):266-270.
20. Man BL,Fu YP,Chan YY,et al.Lesion patterns and stroke mechanisms in concurrent atherosclerosis of intracranial and extracranial vessels[J].Stroke,2009,40(10):3211-3215.
21. 中華醫學會神經病學分會腦血管病學組缺血性腦血管病血管內介入診療指南撰寫組.中國缺血性腦血管病血管內介入診療指南[J].中華神經科雜志,2011,44(12):863-868.

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Risk Factors for Carotid Stenosis in Patients with Ischemic Cerebrovascular Disease

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