• Department of Pharmacy, General Hospital of Chengdu Military Region, Chengdu, Sichuan 610083, P. R. China;
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目的  觀察秦綿祛風膠囊對鵪鶉高尿酸血癥的影響。 方法   通過喂飼用酵母配制的造模飼料造成鵪鶉高尿酸血癥模型,設秦綿祛風膠囊高、中、低3個劑量組并以苯溴馬隆為陽性對照,在造模的同時連續灌胃藥35 d,檢測血中黃嘌呤氧化酶、尿酸、血尿素氮和三酰甘油及糞便中尿酸含量。 結果   模型動物血清中黃嘌呤氧化酶、尿酸和三酰甘油水平及糞便中尿酸含量較正常對照組明顯升高。秦綿祛風膠囊各劑量組均可顯著降低鵪鶉血清中的尿酸和三酰甘油水平,同時升高糞便中尿酸含量,對血清中黃嘌呤氧化酶活性影響不大。 結論  秦綿祛風膠囊具有降脂降尿酸的功能,其機制可能是通過提高動物排泄尿酸的能力,從而降低血中尿酸的含量。

Citation: WANG Shihua,LIANG Rongmei,TAN Yonghong,JIANG Yan.. Effect of Qin-mian Dispelling Wind Capsule on High Uric Acid Hematic Disease Model of Quail. West China Medical Journal, 2013, 28(11): 1686-1688. doi: 10.7507/1002-0179.20130532 Copy

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