Development and Validation of a C0-T1 Three-dimensional Finite Element Model of a Healthy Person Under Physiologic Loads_Journal of Biomedical Engineering

Authors：

WANGHuihao ¹ ,  ZHANHongsheng ¹ , CHENBo ² , SHIYinyu ¹ , LILinghui ¹ , DUGuoqing ¹

1. Shi's Center of Orthopedics and Traumatology, Shuguang Hospital Affiliated to Shanghai University of TCM, Institute of Traumatology & Orthopedics, Shanghai Academy of TCM, Shanghai 201203, China;
2. Institute of Orthopaedics and Traumatology, Shanghai 200025, China;

Corresponding?author：

ZHANHongsheng, Email: zhanhongsheng2010@163.com

Keywords：

cervical spine; finite element model; biomechanics

DOI：

10.7507/1001-5515.20140235

Video：

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A comprehensive, geometrically accurate, nonlinear C0-T1 three-dimensional finite element (FE) model was developed for the biomechanical study of human cervical spine and related disorders. The model was developed with anatomic detail from the computed tomography (CT) images of a 46-year old female healthy volunteer, and applied the finite element model processing softwares such as MIMICS13.1, Hypermesh11.0, Abaqus 6.12-1, etc., for developing, preprocessing, calculating and analysing sequentially. The stress concentration region and the range of motion (ROM) of each vertebral level under axial rotation, flexion, extension, and lateral bending under physiologic static loadings were observed and recorded. The model was proven reliable, which was validated with the range of motion in previous published literatures. The model predicted the front and side parts of the foramen magnum and contralateral pedicle and facet was the stress concentration region under physiological loads of the upper spine and the lower spine, respectively. The development of this comprehensive, geometrically accurate, nonlinear cervical spine FE model could provide an ideal platform for theoretical biomechanical study of human cervical spine and related disorders.

Citation： WANGHuihao, ZHANHongsheng, CHENBo, SHIYinyu, LILinghui, DUGuoqing. Development and Validation of a C0-T1 Three-dimensional Finite Element Model of a Healthy Person Under Physiologic Loads. Journal of Biomedical Engineering, 2014, 31(6): 1238-1242,1249. doi: 10.7507/1001-5515.20140235 Copy

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1. 詹紅生.脊柱整復手法的力學效應研究[J].中國中醫骨傷科雜志,2006,14(S2):225-226.
2. 昌耘冰,徐達傳,尹慶水.頸椎生物力學模型的應用及進展[J].中國臨床解剖學雜志,2003,21(2):187-189.
3. 徐德永,孫錫和.頸椎病發生的解剖學和生物力學基礎[J].臨床放射學雜志,1997,16(2):120-122.
4. PANJABI M M. Cervical spine models for biomechanical research[J]. Spine[J], 1998, 23(24):2684-2699.
5. ZHANG Q H,TEO E C, NG H W. Development and validation of a C0-C7 FE complex for biomechanical study[J]. J Biomech Eng, 2005, 127(5):729-735.
6. BROLIN K, HALLDIN P. Development of a finite element model of the upper cervical spine and a parameter study of ligament characteristics[J]. Spine (Phila Pa 1976), 2004, 29(4):376-385.
7. TENCER A M, BENSEL K. Internal loads in the cervical spine during motor vehicle rear-end impacts:the effect of acceleration and head-to-head restraint proximity[J]. Spine (Phila Pa 1976), 2002, 27(1):34-42.
8. 陳金水,倪斌,陳博,等.寰樞椎脫位三維非線性有限元模型的建立和分析[J].中國脊柱脊髓雜志,2010,20(9):749-753.
9. ZHANG H, BAI J. Development and validation of a finite element model of the occipito-atlantoaxial complex under physiologic loads[J].Spine (Phila Pa 1976), 2007, 32(9):968-974.
10. VAN C M, HUISKES R.骨科生物力學暨力學生物學[M].濟南:山東科學技術出版社,2009:500-503.
11. 賈連順,袁文.現代脊柱外科學[M].北京:人民軍醫出版社,2007:21-24.
12. CARTER D R, HAYES W C. The compressive behavior of bone as a two-phase porous structure[J]. J Bone Joint Surg Am, 1977, 59(7):954-962.
13. HALLDIN P. Prevention and prediction of head and neck injury in traffic accidents-using experimental and numerical methods[D]. Stockholm:KTH, 2001.
14. DVORAK J, SCHNEIDER E, SALDINGER P, et al. Biomechanics of the craniocervical region:the alar and transverse ligaments[J]. J Orthop Res, 1988, 6(3):452-461.
15. LEE C K, KIM Y E, LEE C S, et al. Impact response of the intervertebral disc in a finite-element model[J]. Spine (Phila Pa 1976), 2000, 25(19):2431-2439.
16. SCHMIDT H, KETTLER A, HEUER F, et al. Intradiscal pressure, shear strain, and fiber strain in the intervertebral disc under combined loading[J]. Spine (Phila Pa 1976), 2007, 32(7):748-755.
17. HONG-WAN N, EE-CHON T, QING-HANG Z. Biomechanical effects of C2-C7 intersegmental stability due to laminectomy with unilateral and bilateral facetectomy[J]. Spine (Phila Pa 1976), 2004, 29(16):1737-1745.
18. YOGANANDAN N, KUMARESAN S, PINTAR F A. Biomechanics of the cervical spine Part 2. Cervical spine soft tissue responses and biomechanical modeling[J]. Clin Biomech (Bristol, Avon), 2001, 16(1):1-27.
19. PANJABI M M, CRISCO J J, VASAVADA A, et al. Mechanical properties of the human cervical spine as shown by three-dimensional load-displacement curves[J]. Spine (Phila Pa 1976), 2001, 26(24):2692-2700.
20. BOGDUK N, MERCER S. Biomechanics of the cervical spine.Ⅱ:Normal kinematics[J]. Clin Biomch, 2000, 15(9):633-648.
21. 俞大方.推拿學[M].上海:上海科技出版社,1985:3-5.
22. 張明才,詹紅生,石印玉,等.基于"骨錯縫,筋出槽"診治椎間盤病癥[J].中國骨傷,2008,21(6):441-443.
23. KAWCHUK G N, JHANGRI G S, HURWITZ E L, et al. The relation between the spatial distribution of vertebral artery compromise and exposure to cervical manipulation[J]. J Neurol, 2008, 255(3):371-377.
24. 王輝昊,詹紅生,張明才,等.手法治療頸椎病意外事件分析與預防策略思考[J].中國骨傷,2012,25(9):730-736.
25. 王輝昊,張明才,詹紅生.由脊骨神經醫學發展模式引發的思考[J].中國骨傷,2011,24(8):662-666.
26. HUSSAIN M, NATARAJAN R N, AN H S, et al. Motion changes in adjacent segments due to moderate and severe degeneration in C5-C6 disc:a poroelastic C3-T1 finite element model study[J]. Spine (Phila Pa 1976), 2010, 35(9):939-947.
27. JOZWIK K, OBIDOWSKI D. Numerical simulations of the blood flow through vertebral arteries[J]. J Biomech, 2010, 43(2):177-185.

Journal of Biomedical Engineering

Development and Validation of a C0-T1 Three-dimensional Finite Element Model of a Healthy Person Under Physiologic Loads

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